- Prognostic relevance of 18-F FDG PET/CT in newly diagnosed multiple myeloma patients treated with up-front autologous transplantation
[作者：Zamagni, E; Patriarca, F; Nanni, C; Zannetti, B; Englaro, E; Pezzi, A; Tacchetti, P; Buttignol, S; Perrone, G; Brioli, A; Pantani, L; Terragna, C; Carobolante, F; Baccarani, M; Fanin, R; Fanti, S; Cavo, M,期刊：Blood, 页码：5989-5995 , 文章类型： Article，,卷期：2011年118-23]
- We prospectively analyzed the prognostic relevance of positron emission tomography-computed tomography (PET/CT) at diagnosis, after thalidomide-dexamethasone (TD) induction therapy and double autotransplantation (ASCT) i...
- Glanzmann thrombasthenia: a review of ITGA2B and ITGB3 defects with emphasis on variants, phenotypic variability, and mouse models
[作者：Nurden, AT; Fiore, M; Nurden, P; Pillois, X,期刊：Blood, 页码：5996-6005 , 文章类型： Review，,卷期：2011年118-23]
- Characterized by mucocutaneous bleeding arising from a lack of platelet aggregation to physiologic stimuli, Glanzmann thrombasthenia (GT) is the archetype-inherited disorder of platelets. Transmitted by autosomal recessi...
- Prospective measurement of Epstein-Barr virus-DNA in plasma and peripheral blood mononuclear cells of extranodal NK/T-cell lymphoma, nasal type
[作者：Suzuki, R; Yamaguchi, M; Izutsu, K; Yamamoto, G; Takada, K; Harabuchi, Y; Isobe, Y; Gomyo, H; Koike, T; Okamoto, M; Hyo, R; Suzumiya, J; Nakamura, S; Kawa, K; Oshimi, K,期刊：Blood, 页码：6018-6022 , 文章类型： Article，,卷期：2011年118-23]
- Epstein-Barr virus (EBV)-DNA was prospectively analyzed in plasma and mononuclear cells (MNCs) from peripheral blood in patients with extranodal natural killer (NK)/T-cell lymphoma, nasal type, to evaluate the clinical s...
- Incidence and predictors of congestive heart failure after autologous hematopoietic cell transplantation
[作者：Armenian, SH; Sun, CL; Shannon, T; Mills, G; Francisco, L; Venkataraman, K; Wong, FL; Forman, SJ; Bhatia, S,期刊：Blood, 页码：6023-6029 , 文章类型： Article，,卷期：2011年118-23]
- Advances in autologous hematopoietic cell transplantation (HCT) strategies have resulted in a growing number of long-term survivors. However, these survivors are at increased risk of developing cardiovascular complicatio...
- Phase 1/2 study to assess the safety, efficacy, and pharmacokinetics of barasertib (AZD1152) in patients with advanced acute myeloid leukemia
[作者：Lowenberg, B; Muus, P; Ossenkoppele, G; Rousselot, P; Cahn, JY; Ifrah, N; Martinelli, G; Amadori, S; Berman, E; Sonneveld, P; Jongen-Lavrencic, M; Rigaudeau, S; Stockman, P; Goudie, A; Faderl, S; Jabbour, E; Kantarjian, H,期刊：Blood, 页码：6030-6036 , 文章类型： Article，,卷期：2011年118-23]
- The primary objective of this 2-part phase 1/2 study was to determine the maximum-tolerated dose (MTD) of the potent and selective Aurora B kinase inhibitor barasertib (AZD1152) in patients with newly diagnosed or relaps...
- Autologous peripheral blood stem cell transplantation for acute myeloid leukemia
[作者：Vellenga, E; van Putten, W; Ossenkoppele, GJ; Verdonck, LF; Theobald, M; Cornelissen, JJ; Huijgens, PC; Maertens, J; Gratwohl, A; Schaafsma, R; Schanz, U; Graux, C; Schouten, HC; Ferrant, A; Bargetzi, M; Fey, MF; Lowenberg, B,期刊：Blood, 页码：6037-6042 , 文章类型： Article，,卷期：2011年118-23]
- We report the results of a prospective, randomized phase 3 trial evaluating autologous peripheral blood stem cell transplantation (ASCT) versus intensive consolidation chemotherapy in newly diagnosed AML patients in comp...
- Phase 2 trial of clofarabine in combination with etoposide and cyclophosphamide in pediatric patients with refractory or relapsed acute lymphoblastic leukemia
[作者：Hijiya, N; Thomson, B; Isakoff, MS; Silverman, LB; Steinherz, PG; Borowitz, MJ; Kadota, R; Cooper, T; Shen, V; Dahl, G; Thottassery, JV; Jeha, S; Maloney, K; Paul, JA; Barry, E; Carroll, WL; Gaynon, PS,期刊：Blood, 页码：6043-6049 , 文章类型： Article，,卷期：2011年118-23]
- The outcomes in children with refractory/relapsed (R/R) acute lymphoblastic leukemia (ALL) are dismal. The efficacy and safety of intravenous clofarabine 40 mg/m(2) per day, cyclophosphamide 440 mg/m(2) per day, and etop...
- Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma
[作者：Louis, CU; Savoldo, B; Dotti, G; Pule, M; Yvon, E; Myers, GD; Rossig, C; Russell, HV; Diouf, O; Liu, EL; Liu, H; Wu, MF; Gee, AP; Mei, ZY; Rooney, CM; Heslop, HE; Brenner, MK,期刊：Blood, 页码：6050-6056 , 文章类型： Article，,卷期：2011年118-23]
- We generated MHC-independent chimeric antigen receptors (CARs) directed to the GD2 antigen expressed by neuroblastoma tumor cells and treated patients with this disease. Two distinguishable forms of this CAR were express...
- TNF-alpha/Fas-RIP-1-induced cell death signaling separates murine hematopoietic stem cells/progenitors into 2 distinct populations
[作者：Xiao, YC; Li, HL; Zhang, J; Volk, A; Zhang, SB; Wei, W; Zhang, SS; Breslin, P; Zhang, JW,期刊：Blood, 页码：6057-6067 , 文章类型： Article，,卷期：2011年118-23]
- We studied the effects of TNF-alpha and Fas-induced death signaling in hematopoietic stem and progenitor cells (HSPCs) by examining their contributions to the development of bone marrow failure syndromes in Tak1-knockout...
- Quantitative trait mapping reveals a regulatory axis involving peroxisome proliferator-activated receptors, PRDM16, transforming growth factor-beta 2 and FLT3 in hematopoiesis
[作者：Avagyan, S; Aguilo, F; Kamezaki, K; Snoeck, HW,期刊：Blood, 页码：6078-6086 , 文章类型： Article，,卷期：2011年118-23]
- Hematopoiesis is the process whereby BM HSCs renew to maintain their number or to differentiate into committed progenitors to generate all blood cells. One approach to gain mechanistic insight into this complex process i...
- Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia
[作者：Jaako, P; Flygare, J; Olsson, K; Quere, R; Ehinger, M; Henson, A; Ellis, S; Schambach, A; Baum, C; Richter, J; Larsson, J; Bryder, D; Karlsson, S,期刊：Blood, 页码：6087-6096 , 文章类型： Article，,卷期：2011年118-23]
- Diamond-Blackfan anemia (DBA) is a congenital erythroid hypoplasia caused by a functional haploinsufficiency of genes encoding for ribosomal proteins. Among these genes, ribosomal protein S19 (RPS19) is mutated most freq...
- Acquired STAT4 deficiency as a consequence of cancer chemotherapy
[作者：Lupov, IP; Voiles, L; Han, L; Schwartz, A; De La Rosa, M; Oza, K; Pelloso, D; Sahu, RP; Travers, JB; Robertson, MJ; Chang, HC,期刊：Blood, 页码：6097-6106 , 文章类型： Article，,卷期：2011年118-23]
- Signal Transducer and Activator of Transcription 4 (STAT4) is a transcription factor that is activated by IL-12 signaling and promotes Th1-cell differentiation and IFN-gamma production. Defective IFN-gamma production bec...
- CD5 costimulation induces stable Th17 development by promoting IL-23R expression and sustained STAT3 activation
[作者：de Wit, J; Souwer, Y; van Beelen, AJ; de Groot, R; Muller, FJM; Bos, HK; Jorritsma, T; Kapsenberg, ML; de Jong, EC; van Ham, M,期刊：Blood, 页码：6107-6114 , 文章类型： Article，,卷期：2011年118-23]
- IL-17-producing CD4(+) T helper (Th17) cells are important for immunity against extracellular pathogens and in autoimmune diseases. The factors that drive Th17 development in human remain a matter of debate. Here we show...
- High endothelial venules as traffic control points maintaining lymphocyte population homeostasis in lymph nodes
[作者：Mionnet, C; Sanos, SL; Mondor, I; Jorquera, A; Laugier, JP; Germain, RN; Bajenoff, M,期刊：Blood, 页码：6115-6122 , 文章类型： Article，,卷期：2011年118-23]
- Millions of lymphocytes enter and exit mammal lymph nodes (LNs) each day, accessing the parenchyma via high endothelial venules (HEVs) and egressing via lymphatics. Despite this high rate of cellular flux and the many en...
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