- Metabolic Regulation of Protein N-Alpha-Acetylation by Bcl-xL Promotes Cell Survival
[作者：Yi, CH; Pan, HL; Seebacher, J; Jang, IH; Hyberts, SG; Heffron, GJ; Vander Heiden, MG; Yang, RL; Li, FP; Locasale, JW; Sharfi, H; Zhai, B; Rodriguez-Mias, R; Luithardt, H; Cantley, LC; Daley, GQ; Asara, JM; Gygi, SP; Wagner, G; Liu, CF; Yuan, JY,期刊：Cell, 页码：607-620 , 文章类型： Article，,卷期：2011年146-4]
- Previous experiments suggest a connection between the N-alpha-acetylation of proteins and sensitivity of cells to apoptotic signals. Here, we describe a biochemical assay to detect the acetylation status of proteins and ...
- Structural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons
[作者：Thomas, C; Moraga, I; Levin, D; Krutzik, PO; Podoplelova, Y; Trejo, A; Lee, C; Yarden, G; Vleck, SE; Glenn, JS; Nolan, GP; Piehler, J; Schreiber, G; Garcia, KC,期刊：Cell, 页码：621-632 , 文章类型： Article，,卷期：2011年146-4]
- Type I Interferons (IFNs) are important cytokines for innate immunity against viruses and cancer. Sixteen human type I IFN variants signal through the same cell-surface receptors, IFNAR1 and IFNAR2, yet they can evoke ma...
- Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells
[作者：Gupta, PB; Fillmore, CM; Jiang, GZ; Shapira, SD; Tao, K; Kuperwasser, C; Lander, ES,期刊：Cell, 页码：633-644 , 文章类型： Article，,卷期：2011年146-4]
- Cancer cells within individual tumors often exist in distinct phenotypic states that differ in functional attributes. While cancer cell populations typically display distinctive equilibria in the proportion of cells in v...
- The Human Mitochondrial Transcriptome
[作者：Mercer, TR; Neph, S; Dinger, ME; Crawford, J; Smith, MA; Shearwood, AMJ; Haugen, E; Bracken, CP; Rackham, O; Stamatoyannopoulos, JA; Filipovska, A; Mattick, JS,期刊：Cell, 页码：645-658 , 文章类型： Article，,卷期：2011年146-4]
- The human mitochondrial genome comprises a distinct genetic system transcribed as precursor poly-cistronic transcripts that are subsequently cleaved to generate individual mRNAs, tRNAs, and rRNAs. Here, we provide a comp...
- Linking RNA Polymerase Backtracking to Genome Instability in E. coli
[作者：Dutta, D; Shatalin, K; Epshtein, V; Gottesman, ME; Nudler, E,期刊：Cell, 页码：533-543 , 文章类型： Article，,卷期：2011年146-4]
- Frequent codirectional collisions between the replisome and RNA polymerase (RNAP) are inevitable because the rate of replication is much faster than that of transcription. Here we show that, in E. coli, the outcome of su...
- Dynamic Exchange at Regulatory Elements during Chromatin Remodeling Underlies Assisted Loading Mechanism
[作者：Voss, TC; Schiltz, RL; Sung, MH; Yen, PM; Stamatoyannopoulos, JA; Biddie, SC; Johnson, TA; Miranda, TB; John, S; Hager, GL,期刊：Cell, 页码：544-554 , 文章类型： Article，,卷期：2011年146-4]
- The glucocorticoid receptor (GR), like other eukaryotic transcription factors, regulates gene expression by interacting with chromatinized DNA response elements. Photobleaching experiments in living cells indicate that r...
- The Spatial Arrangement of Chromosomes during Prometaphase Facilitates Spindle Assembly
[作者：Magidson, V; O'Connell, CB; Loncarek, J; Paul, R; Mogilner, A; Khodjakov, A,期刊：Cell, 页码：555-567 , 文章类型： Article，,卷期：2011年146-4]
- Error-free chromosome segregation requires stable attachment of sister kinetochores to the opposite spindle poles (amphitelic attachment). Exactly how amphitelic attachments are achieved during spindle assembly remains e...
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