- Tangled Fibroblasts in Tumor-Stroma interactions
[作者:Liu, M; Xu, JJ; Deng, H,期刊:International Journal of Cancer, 页码:1795-1805 , 文章类型: Review,,卷期:2011年129-8]
- Fibrogenesis, expressed as "desmoplasia," is found in many kinds of tumors and considered to be associated with malignancy. In fact, fibroblasts in cancer stroma have attracted considerable attention in the last 2 decade...
- Induction of mutant p53-dependent apoptosis in human hepatocellular carcinoma by targeting stress protein mortalin
[作者:Lu, WJ; Lee, NP; Kaul, SC; Lan, F; Poon, RTP; Wadhwa, R; Luk, JM,期刊:International Journal of Cancer, 页码:1806-1814 , 文章类型: Article,,卷期:2011年129-8]
- Stress protein mortalin (mtHSP70) is highly expressed in cancer cells. It was shown to contribute to carcinogenesis by sequestrating the wild type p53, a key tumor suppressor protein, in the cytoplasm resulting in an abr...
- Catalytic activity of matrix metalloproteinase-19 is essential for tumor suppressor and anti-angiogenic activities in nasopharyngeal carcinoma
[作者:Chan, KC; Ko, JMY; Lung, HL; Sedlacek, R; Zhang, ZF; Luo, DZ; Feng, ZB; Chen, S; Chen, HL; Chan, KW; Tsao, SW; Chua, DTT; Zabarovsky, ER; Stanbridge, EJ; Lung, ML,期刊:International Journal of Cancer, 页码:1826-1837 , 文章类型: Article,,卷期:2011年129-8]
- The association of Matrix metalloproteinase-19 (MMP19) in the development of nasopharyngeal carcinoma (NPC) was identified from differential gene profiling, which showed MMP19 was one of the candidate genes down-regulate...
- Expression of gangliosides, GD1a, and sialyl paragloboside is regulated by NF-kappa B-dependent transcriptional control of alpha 2,3-sialyltransferase I, II, and VI in human castration-resistant prostate cancer cells
[作者:Hatano, K; Miyamoto, Y; Nonomura, N; Kaneda, Y,期刊:International Journal of Cancer, 页码:1838-1847 , 文章类型: Article,,卷期:2011年129-8]
- Gangliosides are sialic acid-containing glycosphingolipids that are associated with tumor malignancy and progression. Among the enzymes required for the production of gangliosides, sialyltransferases have received much a...
- Frequent genomic loss at chr16p13.2 is associated with poor prognosis in colorectal cancer
[作者:Andersen, CL; Lamy, P; Thorsen, K; Kjeldsen, E; Wikman, F; Villesen, P; Oster, B; Laurberg, S; Omtoft, TF,期刊:International Journal of Cancer, 页码:1848-1858 , 文章类型: Article,,卷期:2011年129-8]
- Genomic alterations play important roles in colorectal cancer (CRC) carcinogenesis. Here, we aimed to identify and characterize recurrent copy-number alterations (CNAs) associated with clinical outcome of CRC by the use ...
- Inactivation of CHEK1 and EI24 is associated with the development of invasive cervical carcinoma: clinical and prognostic implications
[作者:Mazumder, D; Mitra, S; Singh, RK; Dutta, S; Roy, A; Mondal, RK; Basu, PS; Roychoudhury, S; Panda, CK,期刊:International Journal of Cancer, 页码:1859-1871 , 文章类型: Article,,卷期:2011年129-8]
- To understand the importance of frequent deletion of chromosomal 11q23.3-24.3 region in cervical carcinogenesis, alterations (deletion/methylation/mutation/expression) of the candidate genes LOH11CR2A, EI24 and CHEK1 loc...
- Two survivin polymorphisms are cooperatively associated with bladder cancer susceptibility
[作者:Kawata, N; Tsuchiya, N; Horikawa, Y; Inoue, T; Tsuruta, H; Maita, S; Satoh, S; Mitobe, Y; Narita, S; Habuchi, T,期刊:International Journal of Cancer, 页码:1872-1880 , 文章类型: Article,,卷期:2011年129-8]
- Abnormal survivin expression has been reported to be involved in many types of cancer. A single-nucleotide polymorphism (SNP), C-31G, located in the promoter region of survivin reportedly may alter the mRNA level, while ...
- Sessile serrated adenomas and classical adenomas: an epigenetic perspective on premalignant neoplastic lesions of the gastrointestinal tract
[作者:Dhir, M; Yachida, S; Van Neste, L; Glockner, SC; Jeschke, J; Pappou, EP; Montgomery, EA; Herman, JG; Baylin, SB; Iacobuzio-Donahue, C; Ahuja, N,期刊:International Journal of Cancer, 页码:1889-1898 , 文章类型: Article,,卷期:2011年129-8]
- The diagnosis of sessile serrated adenomas (SSAs) is challenging, and there is a great deal of interobserver variability amongst pathologists in differentiating SSAs from hyperplastic polyps (HPPs). The aim of this study...
- Serological AFP/Golgi protein 73 could be a new diagnostic parameter of hepatic diseases
[作者:Tian, LY; Wang, Y; Xu, DB; Gui, JH; Jia, XW; Tong, HL; Wen, XY; Dong, ZN; Tian, YP,期刊:International Journal of Cancer, 页码:1923-1931 , 文章类型: Article,,卷期:2011年129-8]
- We have investigated the changing rule of serum form of GP73 (sGP73) in different hepato-pathologic processes and identified the sGP73 role in inflammation, fibrosis and carcinogenesis since sGP73 has been regarded as a ...
- Reduced allergy and immunoglobulin E among adults with intracranial meningioma compared to controls
[作者:Wiemels, JL; Wrensch, M; Sison, JD; Zhou, M; Bondy, M; Calvocoressi, L; Black, PM; Yu, H; Schildkraut, JM; Claus, EB,期刊:International Journal of Cancer, 页码:1932-1939 , 文章类型: Article,,卷期:2011年129-8]
- Meningioma, the most frequent tumor in the central nervous system, has few recognized risk factors. We explored the role of allergies in a population-based case-control consortium study of meningioma in five geographic a...
- Second malignancies after childhood noncentral nervous system solid cancer: results from 13 cancer registries
[作者:Maule, M; Scelo, G; Pastore, G; Brennan, P; Hemminki, K; Olsen, JH; Tracey, E; Pukkala, E; Weiderpass, E; Brewster, DH; Tamaro, S; Chia, KS; Pompe-Kirn, V; Kliewer, EV; Tonita, JM; Martos, C; Jonasson, JG; Merletti, F; Boffetta, P,期刊:International Journal of Cancer, 页码:1940-1952 , 文章类型: Article,,卷期:2011年129-8]
- Children diagnosed with noncentral nervous system solid cancers (NCNSSC) experience several adverse late effects, including second malignant neoplasm. The aim of our study was to assess the risk of specific second malign...
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