- Coevolution: Mankind and microbes
[作者：Mitscher, LA,期刊：Journal of natural products, 页码：497-509 , 文章类型： Review，,卷期：2008年71-3]
- In just 70 short years mankind has progressed from euphoria to despair over the effectiveness of antibiotics to protect and to cure mankind from morbidity and mortality from infectious diseases. Resistance due to evoluti...
- Efficacy of selected natural products as therapeutic agents against cancer
[作者：Banerjee, S; Wang, Z; Mohammad, M; Sarkar, FH; Mohammad, RM,期刊：Journal of natural products, 页码：492-496 , 文章类型： Review，,卷期：2008年71-3]
- With emerging sophistication in the exploration of ocean environment, a number of marine bioactive products have been identified with promising anticancer activity. Many of these are in active phase I or phase 11 clinica...
- Semisynthetic studies on the manzamine alkaloids
[作者：El Sayed, KA; Khalil, AA; Yousaf, M; Labadie, G; Kumar, GM; Franzblau, SG; Mayer, AMS; Avery, MA; Hamann, MT,期刊：Journal of natural products, 页码：300-308 , 文章类型： Article，,卷期：2008年71-3]
- Chemical transformation studies were conducted on (-)-8-hydroxymanzamine A (1), (-)-manzamine F (2), manzamine A (3), and (+)-8-hydroxymanzamine A (4), isolated from Indo-Pacific Acanthostrongylophora sponges.' Thirteen ...
- Cytotoxic bastadin 24 from the Australian sponge Ianthella quadrangulata
[作者：Greve, H; Kehraus, S; Krick, A; Keller, G; Maier, A; Fiebig, HH; Wright, AD; Konig, GM,期刊：Journal of natural products, 页码：309-312 , 文章类型： Article，,卷期：2008年71-3]
- A new cytotoxic bastadin, bastadin 24 (1), and the previously reported bastadins 4, 5, 6, 7, 12, 13, and 21 (2-8) were isolated from a polar extract of the Australian marine sponge Ianthella quadrangulata. The planar str...
- Antiproliferative limonoids of a Malleastrum sp from the Madagascar rainforest
[作者：Murphy, BT; Brodie, P; Slebodnick, C; Miller, JS; Birkinshaw, C; Randrianjanaka, LM; Andriantsiferana, R; Rasamison, VE; TenDyke, K; Suh, EM; Kingston, DGI,期刊：Journal of natural products, 页码：325-329 , 文章类型： Article，,卷期：2008年71-3]
- Bicassay-guided fractionation of an ethanol extract of a Malleastrum sp. afforded three new limonoids, malleastrones A-C (1-3), respectively. Each limonoid contained a rare tetranortriterpenoid skeleton. Structure elucid...
- Combretastatin dinitrogen-substituted stilbene analogues as tubulin-binding and vascular-disrupting agents
[作者：Siles, R; Ackley, JF; Hadimani, MB; Hall, JJ; Mugabe, BE; Guddneppanavar, R; Monk, KA; Chapuis, JC; Pettit, GR; Chaplin, DJ; Edvardsen, K; Trawick, ML; Garner, CM; Pinney, KG,期刊：Journal of natural products, 页码：313-320 , 文章类型： Article，,卷期：2008年71-3]
- Several stilbenoid compounds having structural similarity to the combretastatin group of natural products and characterized by the incorporation of two nitrogen-bearing groups (amine, nitro, serinamide) have been prepare...
- Sodium pancratistatin 3,4-O-cyclic phosphate, a water-soluble synthetic derivative of pancratistatin, is highly effective in a human colon tumor model
[作者：Shnyder, SD; Cooper, PA; Millington, NJ; Gill, JH; Bibby, MC,期刊：Journal of natural products, 页码：321-324 , 文章类型： Article，,卷期：2008年71-3]
- Sodium pancratistatin 3,4-O-cyclic phosphate (2) is a novel water-soluble synthetic derivative of pancratistatin (1), a natural alkaloid constituent of Amaryllidaceae plants, that exhibits good cytostatic and antineoplas...
- Gymnastatins and dankastatins, growth inhibitory metabolites of a Gymnascella species from a Halichondria sponge
[作者：Amagata, T; Tanaka, M; Yamada, T; Minoura, K; Numata, A,期刊：Journal of natural products, 页码：340-345 , 文章类型： Article，,卷期：2008年71-3]
- Four new metabolites, gymnastatins Q (3) and R (4) and dankastatins A (5) and B (6), have been isolated from the mycelial MeOH extract of a fungal strain of Gymnascella dankaliensis separated from a Halichondria sponge. ...
- Antifouling activity of a dibrominated cyclopeptide from the marine sponge Geodia barretti
[作者：Hedner, E; Sjogren, M; Hodzic, S; Andersson, R; Goransson, U; Jonsson, PR; Bohlin, L,期刊：Journal of natural products, 页码：330-333 , 文章类型： Article，,卷期：2008年71-3]
- Many sessile suspension-feeding marine organisms rely on chemical defense to keep their surfaces free from fouling organisms. The brominated cyclopeptides barettin (cyclo[(6-bromo-8-entryptophan)arginine]) (1) and 8,9-di...
- Antiparasitic, antineuroinflammatory, and cytotoxic polyketides from the marine sponge Plakortis angulospiculatus collected in Brazil
[作者：Kossuga, MH; Nascimento, AM; Reimao, JQ; Tempone, AG; Taniwaki, NN; Veloso, K; Ferreira, AG; Cavalcanti, BC; Pessoa, C; Moraes, MO; Mayer, AMS; Hajdu, E; Berlinck, RGS,期刊：Journal of natural products, 页码：334-339 , 文章类型： Article，,卷期：2008年71-3]
- Investigation of the bioactive crude extract from the sponge Plakortis angulospiculatus from Brazil led to the isolation of plakortenone (1) as a new polyketide, along with five known polyketides (2-6) previously isolate...
- Constituents of the sea cucumber Cucumaria okhotensis. Structures of okhotosides B-1-B-3 and cytotoxic activities of some glycosides from this species
[作者：Silchenko, AS; Avilov, SA; Kalinin, VI; Kalinovsky, AI; Dmitrenok, PS; Fedorov, SN; Stepanov, VG; Dong, Z; Stonik, VA,期刊：Journal of natural products, 页码：351-356 , 文章类型： Article，,卷期：2008年71-3]
- Three new triterpene oligoglycosides, okhotosides 131 (1), 132 (2), and 133 (3), have been isolated from the sea cucumber Cucumaria okhotensis along with the known compounds frondoside A (4), frondoside A,, cucumarioside...
- Synthesis and biological evaluation of 10,11-dihydrodictyostatin, a potent analogue of the marine anticancer agent dictyostatin
[作者：Paterson, I; Gardner, NM; Poullennec, KG; Wright, AE,期刊：Journal of natural products, 页码：364-369 , 文章类型： Article，,卷期：2008年71-3]
- By employing a diverted total synthesis strategy with late-stage intermediates, 10,1 1-dihydrodictyostatin (5) was prepared and evaluated in vitro for growth inhibition against a range.of human cancer cell lines, includi...
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