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  • Activation of Telomerase by Human Cytomegalovirus
    [作者:Straat, K; Liu, C; Rahbar, A; Zhu, QJ; Liu, L; Wolmer-Solberg, N; Lou, FL; Liu, ZX; Shen, J; Jia, JH; Kyo, S; Bjorkholm, M; Sjoberg, J; Soderberg-Naucler, C; Xu, DW,期刊:Journal of the National Cancer Institute, 页码:488-497 , 文章类型: Article,,卷期:2009年101-7]
  • The mechanism by which human cytomegalovirus (HCMV) stimulates oncogenesis is unclear. Because cellular immortalization and transformation require telomerase activation by expression of the telomerase reverse transcripta...
  • Fatty Acid Synthase: A Metabolic Enzyme and Candidate Oncogene in Prostate Cancer
    [作者:Migita, T; Ruiz, S; Fornari, A; Fiorentino, M; Priolo, C; Zadra, G; Inazuka, F; Grisanzio, C; Palescandolo, E; Shin, E; Fiore, C; Xie, W; Kung, AL; Febbo, PG; Subramanian, A; Mucci, L; Ma, J; Signoretti, S; Stampfer, M; Hahn, WC; Finn, S; Loda, M,期刊:Journal of the National Cancer Institute, 页码:519-532 , 文章类型: Article,,卷期:2009年101-7]
  • Overexpression of the fatty acid synthase (FASN) gene has been implicated in prostate carcinogenesis. We sought to directly assess the oncogenic potential of FASN.We used immortalized human prostate epithelial cells (iPr...