- Pharmacodynamic-Pharmacokinetic Integration as a Guide to Medicinal Chemistry
[作者:Gabrielsson, J; Fjellstrom, O; Ulander, J; Rowley, M; Van der Graaf, PH,期刊:Current Topics in Medicinal Chemistry, 页码:404-418 , 文章类型: Review,,卷期:2011年11-4]
- A primary objective of pharmacokinetic-pharmacodynamic (PKPD) reasoning is to identify key in vivo drug and system properties, enabling prediction of the magnitude and time course of drug responses under physiological an...
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