- Identification of putative dental epithelial stem cells in a lizard with life-long tooth replacement
[作者:Handrigan, GR; Leung, KJ; Richman, JM,期刊:Development, 页码:3545-3549 , 文章类型: Article,,卷期:2010年137-21]
- Most dentate vertebrates, including humans, replace their teeth and yet the process is poorly understood. Here, we investigate whether dental epithelial stem cells exist in a polyphyodont species, the leopard gecko (Eubl...
- Oct1 regulates trophoblast development during early mouse embryogenesis
[作者:Sebastiano, V; Dalvai, M; Gentile, L; Schubart, K; Sutter, J; Wu, GM; Tapia, N; Esch, D; Ju, JY; Hubner, K; Bravo, MJA; Scholer, HR; Cavaleri, F; Matthias, P,期刊:Development, 页码:3551-3560 , 文章类型: Article,,卷期:2010年137-21]
- Oct1 (Pou2f1) is a transcription factor of the POU-homeodomain family that is unique in being ubiquitously expressed in both embryonic and adult mouse tissues. Although its expression profile suggests a crucial role in m...
- Serpent, Suppressor of Hairless and U-shaped are crucial regulators of hedgehog niche expression and prohemocyte maintenance during Drosophila larval hematopoiesis
[作者:Tokusumi, Y; Tokusumi, T; Stoller-Conrad, J; Schulz, RA,期刊:Development, 页码:3561-3568 , 文章类型: Article,,卷期:2010年137-21]
- The lymph gland is a specialized organ for hematopoiesis, utilized during larval development in Drosophila. This tissue is composed of distinct cellular domains populated by blood cell progenitors (the medullary zone), n...
- WUSCHEL mediates stem cell homeostasis by regulating stem cell number and patterns of cell division and differentiation of stem cell progenitors
[作者:Yadav, RK; Tavakkoli, M; Reddy, GV,期刊:Development, 页码:3581-3589 , 文章类型: Article,,卷期:2010年137-21]
- Plant stem cell populations, unlike their animal counterparts, do not use cell migration and oriented cell divisions to maintain their size, and therefore require a precise coordination between self-renewing divisions of...
- The C. elegans peroxidasin PXN-2 is essential for embryonic morphogenesis and inhibits adult axon regeneration
[作者:Gotenstein, JR; Swale, RE; Fukuda, T; Wu, ZL; Giurumescu, CA; Goncharov, A; Jin, YS; Chisholm, AD,期刊:Development, 页码:3603-3613 , 文章类型: Article,,卷期:2010年137-21]
- Peroxidasins form a highly conserved family of extracellular peroxidases of unknown cellular function. We identified the C. elegans peroxidasin PXN-2 in screens for mutants defective in embryonic morphogenesis. We find t...
- Notch signalling regulates left-right asymmetry through ciliary length control
[作者:Lopes, SS; Lourenco, R; Pacheco, L; Moreno, N; Kreiling, J; Saude, L,期刊:Development, 页码:3625-3632 , 文章类型: Article,,卷期:2010年137-21]
- The importance of cilia in embryonic development and adult physiology is emphasized by human ciliopathies. Despite its relevance, molecular signalling pathways behind cilia formation are poorly understood. We show that N...
- On reconciling the interactions between APETALA2, miR172 and AGAMOUS with the ABC model of flower development
[作者:Wollmann, H; Mica, E; Todesco, M; Long, JA; Weigel, D,期刊:Development, 页码:3633-3642 , 文章类型: Article,,卷期:2010年137-21]
- The ABC model of flower development explains how three classes of homeotic genes confer identity to the four types of floral organs. In Arabidopsis thaliana, APETALA2 (AP2) and AGAMOUS (AG) represent A- and C-class genes...
- The Flamingo ortholog FMI-1 controls pioneer-dependent navigation of follower axons in C. elegans
[作者:Steimel, A; Wong, LN; Najarro, EH; Ackley, BD; Garriga, G; Hutter, H,期刊:Development, 页码:3663-3673 , 文章类型: Article,,卷期:2010年137-21]
- Development of a functional neuronal network during embryogenesis begins with pioneer axons creating a scaffold along which later-outgrowing axons extend. The molecular mechanism used by these follower axons to navigate ...
- Survival strategies of a sterol auxotroph
[作者:Carvalho, M; Schwudke, D; Sampaio, JL; Palm, W; Riezman, I; Dey, G; Gupta, GD; Mayor, S; Riezman, H; Shevchenko, A; Kurzchalia, TV; Eaton, S,期刊:Development, 页码:3675-3685 , 文章类型: Article,,卷期:2010年137-21]
- The high sterol concentration in eukaryotic cell membranes is thought to influence membrane properties such as permeability, fluidity and microdomain formation. Drosophila cannot synthesize sterols, but do require them f...
- Expression and function of the empty spiracles gene in olfactory sense organ development of Drosophila melanogaster
[作者:Sen, S; Hartmann, B; Reichert, H; Rodrigues, V,期刊:Development, 页码:3687-3695 , 文章类型: Article,,卷期:2010年137-21]
- In Drosophila, the cephalic gap gene empty spiracles plays key roles in embryonic patterning of the peripheral and central nervous system. During postembryonic development, it is involved in the development of central ol...
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