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  • Total Synthesis of Sanguiin H-5.
    [作者:Su, Xianbin;Surry, David S.;Spandl, Richard J.;Spring, David R.;,期刊:Organic Letters, 页码:2593-2596 , 文章类型: 研究论文,,卷期:2008年10-12]
  • Using an atropdiastereoselective oxidative biaryl coupling as the key step, the total synthesis of the ellagitannin natural product sanguiin H-5 is reported. Both organomagnesium and organozinc based metalation methodol...
  • Total Synthesis of cis-Sylvaticin.
    [作者:Brown, Lynda J.;Spurr, Ian B.;Kemp, Stephen C.;Camp, Nicholas P.;Gibson, Karl R.;Brown, Richard C. D.;,期刊:Organic Letters, 页码:2489-2492 , 文章类型: 研究论文,,卷期:2008年10-12]
  • An asym. total synthesis of (+)-cis-sylvaticin [I, X = (CH2)7, Y = (CH2)9] is described. Key steps include the use of permanganate-mediated oxidative cyclization of 1,5-dienes to synthesize the two major fragments II an...
  • Total Synthesis of the Hsp90 Inhibitor Geldanamycin.
    [作者:Qin, Hua-Li;Panek, James S.;,期刊:Organic Letters, 页码:2477-2479 , 文章类型: 研究论文,,卷期:2008年10-12]
  • An enantioselective synthesis of the Hsp90 inhibitor geldanamycin (I) was achieved in 20 linear steps and 2.0% overall yield from 2-methoxyhydroquinone. The synthesis is highlighted by a regio- and stereoselective hydro...
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