- Randomized phase III study 306 Adjunctive perampanel for refractory partial-onset seizures
[作者：Krauss, GL; Serratosa, JM; Villanueva, V; Endziniene, M; Hong, Z; French, J; Yang, H; Squillacote, D; Edwards, HB; Zhu, J; Laurenza, A,期刊：Neurology, 页码：1408-1415 , 文章类型： Article，,卷期：2012年78-18]
- Objective: To evaluate the efficacy and safety of perampanel 2, 4, and 8 mg/day added to 1-3 concomitant antiepileptic drugs (AEDs) in patients with uncontrolled partial-onset seizures. Methods: During this double-blind,...
- Simultaneous PML-IRIS after discontinuation of natalizumab in a patient with MS
[作者：Gheuens, S; Smith, DR; Wang, X; Alsop, DC; Lenkinski, RE; Koralnik, IJ,期刊：Neurology, 页码：1390-1393 , 文章类型： Article，,卷期：2012年78-18]
- Objective: Progressive multifocal leukoencephalopathy (PML) is a severe complication of natalizumab therapy in patients with multiple sclerosis (MS), which is often accompanied by an immune reconstitution inflammatory sy...
- Functional reorganization of sensorimotor cortex in early Parkinson disease
[作者：Kojovic, M; Bologna, M; Kassavetis, P; Murase, N; Palomar, FJ; Berardelli, A; Rothwell, JC; Edwards, MJ; Bhatia, KP,期刊：Neurology, 页码：1441-1448 , 文章类型： Article，,卷期：2012年78-18]
- Objective: Compensatory reorganization of the nigrostriatal system is thought to delay the onset of symptoms in early Parkinson disease (PD). Here we sought evidence that compensation may be a part of a more widespread f...
- GFAP and S100B in the acute phase of mild traumatic brain injury
[作者：Metting, Z; Wilczak, N; Rodiger, LA; Schaaf, JM; van der Naalt, J,期刊：Neurology, 页码：1428-1433 , 文章类型： Article，,卷期：2012年78-18]
- Objective: The biomarkers glial fibrillary acid protein (GFAP) and S100B are increasingly used as prognostic tools in severe traumatic brain injury (TBI). Data for mild TBI are scarce. This study aims to analyze the pred...
- Two-year serial whole-brain N-acetyl-L-aspartate in patients with relapsing-remitting multiple sclerosis
[作者：Rigotti, DJ; Inglese, M; Kirov, II; Gorynski, E; Perry, NN; Babb, JS; Herbert, J; Grossman, RI; Gonen, O,期刊：Neurology, 页码：1383-1389 , 文章类型： Article，,卷期：2012年78-18]
- Objectives: To test the hypotheses that 1) patients with relapsing-remitting multiple sclerosis (RR-MS) exhibit a quantifiable decline in their whole-brain concentration of the neural marker N-acetyl-L-aspartate (WBNAA),...
- Impact of therapeutic hypothermia on MRI diffusion changes in neonatal encephalopathy
[作者：Bednarek, N; Mathur, A; Inder, T; Wilkinson, J; Neil, J; Shimony, J,期刊：Neurology, 页码：1420-1427 , 文章类型： Article，,卷期：2012年78-18]
- Objective: The objective of this work was to determine the impact of therapeutic hypothermia (TH) on the magnitude and time course of mean diffusivity (MD) changes following hypoxic-ischemic encephalopathy (HIE) in newbo...
- Cognitive performance of GBA mutation carriers with early-onset PD The CORE-PD study
[作者：Alcalay, RN; Caccappolo, E; Mejia-Santana, H; Tang, MX; Rosado, L; Reilly, MO; Ruiz, D; Ross, B; Verbitsky, M; Kisselev, S; Louis, E; Comella, C; Colcher, A; Jennings, D; Nance, M; Bressman, S; Scott, WK; Tanner, C; Mickel, S; Andrews, H; Waters, C; Fahn, S; Cote, L; Frucht, S; Ford, B; Rezak, M; Novak, K; Friedman, JH; Pfeiffer, R; Marsh, L; Hiner, B; Siderowf, A; Payami, H; Molho, E; Factor, S; Ottman, R; Clark, LN; Marder, K,期刊：Neurology, 页码：1434-1440 , 文章类型： Article，,卷期：2012年78-18]
- Objective: To assess the cognitive phenotype of glucocerebrosidase (GBA) mutation carriers with early-onset Parkinson disease (PD). Methods: We administered a neuropsychological battery and the University of Pennsylvania...
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