- RANKL Increases Vascular Smooth Muscle Cell Calcification Through a RANK-BMP4-Dependent Pathway
[作者:Panizo, S; Cardus, A; Encinas, M; Parisi, E; Valcheva, P; Lopez-Ongil, S; Coll, B; Fernandez, E; Valdivielso, JM,期刊:Circulation Research, 页码:1041-1048 , 文章类型: Article,,卷期:2009年104-9]
- Vascular calcification commonly associated with several pathologies and it has been suggested to be similar to bone mineralization. The axis RANKL-OPG (receptor activator of nuclear factor kappa B ligand-osteoprotegerin)...
- Antiinflammatory Effects of the ETS Factor ERG in Endothelial Cells Are Mediated Through Transcriptional Repression of the Interleukin-8 Gene
[作者:Yuan, L; Nikolova-Krstevski, V; Zhan, Y; Kondo, M; Bhasin, M; Varghese, L; Yano, K; Carman, CV; Aird, WC; Oettgen, P,期刊:Circulation Research, 页码:1049-U63 , 文章类型: Article,,卷期:2009年104-9]
- ERG (Ets-related gene) is an ETS transcription factor that has recently been shown to regulate a number of endothelial cell (EC)-restricted genes including VE-cadherin, von Willebrand factor, endoglin, and intercellular ...
- Adiponectin Suppresses Pathological Microvessel Formation in Retina Through Modulation of Tumor Necrosis Factor-alpha Expression
[作者:Higuchi, A; Ohashi, K; Kihara, S; Walsh, K; Ouchi, N,期刊:Circulation Research, 页码:1058-1065 , 文章类型: Article,,卷期:2009年104-9]
- The fat-derived hormone adiponectin has been shown to have a protective role in macrovascular disorders. However, nothing is known about the function of adiponectin in retinal microvessel disease. Here, we investigated t...
- A Role for Gab1/SHP2 in Thrombin Activation of PAK1 Gene Transfer of Kinase-Dead PAK1 Inhibits Injury-Induced Restenosis
[作者:Wang, D; Paria, BC; Zhang, QH; Karpurapu, M; Li, QY; Gerthoffer, WT; Nakaoka, Y; Rao, GN,期刊:Circulation Research, 页码:1066-U90 , 文章类型: Article,,卷期:2009年104-9]
- To understand the role of epidermal growth factor receptor (EGFR) transactivation in G protein-coupled receptor (GPCR) agonist -induced signaling events, we have studied the capacity of thrombin in the activation of Gab1...
- Genetic Fate Mapping Identifies Second Heart Field Progenitor Cells As a Source of Adipocytes in Arrhythmogenic Right Ventricular Cardiomyopathy
[作者:Lombardi, R; Dong, JJ; Rodriguez, G; Bell, A; Leung, TK; Schwartz, RJ; Willerson, JT; Brugada, R; Marian, AJ,期刊:Circulation Research, 页码:1076-U120 , 文章类型: Article,,卷期:2009年104-9]
- The phenotypic hallmark of arrhythmogenic right ventricular cardiomyopathy, a genetic disease of desmosomal proteins, is fibroadipocytic replacement of the right ventricle. Cellular origin of excess adipocytes, the respo...
- Contribution of Insulin and Akt1 Signaling to Endothelial Nitric Oxide Synthase in the Regulation of Endothelial Function and Blood Pressure
[作者:Symons, JD; McMillin, SL; Riehle, C; Tanner, J; Palionyte, M; Hillas, E; Jones, D; Cooksey, RC; Birnbaum, MJ; McClain, DA; Zhang, QJ; Gale, D; Wilson, LJ; Abel, ED,期刊:Circulation Research, 页码:1085-U153 , 文章类型: Article,,卷期:2009年104-9]
- Impaired insulin signaling via phosphatidylinositol 3-kinase/Akt to endothelial nitric oxide synthase (eNOS) in the vasculature has been postulated to lead to arterial dysfunction and hypertension in obesity and other in...
- Human CD133(+) Progenitor Cells Promote the Healing of Diabetic Ischemic Ulcers by Paracrine Stimulation of Angiogenesis and Activation of Wnt Signaling
[作者:Barcelos, LS; Duplaa, C; Krankel, N; Graiani, G; Invernici, G; Katare, R; Siragusa, M; Meloni, M; Campesi, I; Monica, M; Simm, A; Campagnolo, P; Mangialardi, G; Stevanato, L; Alessandri, G; Emanueli, C; Madeddu, P,期刊:Circulation Research, 页码:1095-U199 , 文章类型: Article,,卷期:2009年104-9]
- We evaluated the healing potential of human fetal aorta-derived CD133(+) progenitor cells and their conditioned medium (CD133(+) CCM) in a new model of ischemic diabetic ulcer. Streptozotocin-induced diabetic mice underw...
- Structural and Molecular Mechanisms of Gap Junction Remodeling in Epicardial Border Zone Myocytes following Myocardial Infarction
[作者:Kieken, F; Mutsaers, N; Dolmatova, E; Virgil, K; Wit, AL; Kellezi, A; Hirst-Jensen, BJ; Duffy, HS; Sorgen, PL,期刊:Circulation Research, 页码:1103-U219 , 文章类型: Article,,卷期:2009年104-9]
- Lateralization of the ventricular gap junction protein connexin 43 (Cx43) occurs in epicardial border zone myocytes following myocardial infarction (MI) and is arrhythmogenic. Alterations in Cx43 protein partners have be...
- Ion Channel Subunit Expression Changes in Cardiac Purkinje Fibers A Potential Role in Conduction Abnormalities Associated With Congestive Heart Failure
[作者:Maguy, A; Le Bouter, S; Comtois, P; Chartier, D; Villeneuve, L; Wakili, R; Nishida, K; Nattel, S,期刊:Circulation Research, 页码:1113-U246 , 文章类型: Article,,卷期:2009年104-9]
- Purkinje fibers (PFs) play key roles in cardiac conduction and arrhythmogenesis. Congestive heart failure (CHF) causes well-characterized atrial and ventricular ion channel subunit expression changes, but effects on PF i...
- TRPV4 Channels Mediate Cyclic Strain-Induced Endothelial Cell Reorientation Through Integrin-to-Integrin Signaling
[作者:Thodeti, CK; Matthews, B; Ravi, A; Mammoto, A; Ghosh, K; Bracha, AL; Ingber, DE,期刊:Circulation Research, 页码:1123-U278 , 文章类型: Article,,卷期:2009年104-9]
- Cyclic mechanical strain produced by pulsatile blood flow regulates the orientation of endothelial cells lining blood vessels and influences critical processes such as angiogenesis. Mechanical stimulation of stretch-acti...
- Angiopoietin-1 opposes VEGF-induced increase in endothelial permeability by inhibiting TRPC1-dependent Ca-2 influx (vol 96, pg 1282, 2005)
[作者:Jho, D; Mehta, D; Ahmmed, G; Gao, XP; Tiruppathi, C; Broman, M; Malik, AB,期刊:Circulation Research, 页码:E58-E58 , 文章类型: Correction,,卷期:2009年104-9]
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