- Fc Gamma Receptor Signaling in Mast Cells Links Microbial Stimulation to Mucosal Immune Inflammation in the Intestine
[作者：Chen, X; Feng, BS; Zheng, PY; Liao, XQ; Chong, J; Tang, SG; Yang, PC,期刊：American Journal of Pathology, 页码：1647-1656 , 文章类型： Article，,卷期：2008年173-6]
- Microbes and microbial products are closely associated with the pathogenesis of inflammatory bowel disease (IBD); however, the mechanisms behind this connection remain unclear. it has been previously reported that flagel...
- Immunological Mechanisms Underlying the Genetic Predisposition to Severe Staphylococcus aureus Infection in the Mouse Model
[作者：von Kockritz-Blickwede, M; Rohde, M; Oehmcke, S; Miller, LS; Cheung, AL; Herwald, H; Foster, S; Medina, E,期刊：American Journal of Pathology, 页码：1657-1668 , 文章类型： Article，,卷期：2008年173-6]
- Host genetic variations play a significant role in conferring predisposition to infection. in this study, we examined the immune mechanisms underlying the host genetic predisposition to severe Staphylococcus aureus infec...
- After Injection into the Striatum, in Vitro-Differentiated Microglia- and Bone Marrow-Derived Dendritic Cells Can Leave the Central Nervous System via the Blood Stream
[作者：Hochmeister, S; Zeitelhofer, M; Bauer, J; Nicolussi, EM; Fischer, MT; Heinke, B; Selzer, E; Lassmann, H; Bradl, M,期刊：American Journal of Pathology, 页码：1669-1681 , 文章类型： Article，,卷期：2008年173-6]
- The prototypic migratory trail of tissue-resident dendritic cells (DCs) is via lymphatic drainage. Since the central nervous system (CNS) lacks classical lymphatic vessels, and antigens and cells injected into both the C...
- Increased Foxp3(+) CD4(+) Regulatory T Cells with Intact Suppressive Activity but Altered Cellular Localization in Murine Lupus
[作者：Abe, J; Ueha, S; Suzuki, J; Tokano, Y; Matsushima, K; Ishikawa, S,期刊：American Journal of Pathology, 页码：1682-1692 , 文章类型： Article，,卷期：2008年173-6]
- Foxp3(+) CD4(+) regulatory T (T-reg) cells play a pivotal role in the maintenance of dominant self tolerance. Understanding how the failures of immune control by T-reg cells are involved in autoimmune diseases is importa...
- Genetic Inversion in Mast Cell-Deficient W-sh Mice Interrupts Corin and Manifests as Hematopoietic and Cardiac Aberrancy
[作者：Nigrovic, PA; Gray, DHD; Jones, T; Hallgren, J; Kuo, FC; Chaletzky, B; Gurish, M; Mathis, D; Benoist, C; Lee, DM,期刊：American Journal of Pathology, 页码：1693-1701 , 文章类型： Article，,卷期：2008年173-6]
- Mast cells participate in pathophysiological processes that range from antimicrobial defense to anaphylaxis and inflammatory arthritis. Much of the groundwork for the understanding of mast cells was established in mice t...
- Therapeutic Effect of Melatonin in Experimental Uveitis
[作者：Sande, PH; Fernandez, DC; Marcos, HJA; Chianelli, MS; Aisemberg, J; Silberman, DM; Saenz, DA; Rosenstein, RE,期刊：American Journal of Pathology, 页码：1702-1713 , 文章类型： Article，,卷期：2008年173-6]
- Uveitis is a common ophthalmic disorder that can be induced in hamsters by a single intravitreal injection of bacterial lipopolysaccharide (LPS). To examine the therapeutic effects of melatonin on uveitis, a pellet of me...
- NKT Cell-Dependent Amelioration of a Mouse Model of Multiple Sclerosis by Altering Gut Flora
[作者：Yokote, H; Miyake, S; Croxford, JL; Oki, S; Mizusawa, H; Yamamura, T,期刊：American Journal of Pathology, 页码：1714-1723 , 文章类型： Article，,卷期：2008年173-6]
- Improved hygiene has been suggested to influence certain autoimmune disorders, such as multiple sclerosis. In this study, we addressed whether altering the composition of gut flora may affect susceptibility to experiment...
- Membrane Protected Apoptotic Trophoblast Microparticles Contain Nucleic Acids Relevance to Preeclampsia
[作者：Orozco, AF; Jorgez, CJ; Horne, C; Marquez-Do, DA; Chapman, MR; Rodgers, JR; Bischoff, FZ; Lewis, DE,期刊：American Journal of Pathology, 页码：1595-1608 , 文章类型： Article，,卷期：2008年173-6]
- Microparticles (MPs) that circulate in blood may be a source of DNA for molecular analyses, including prenatal genetic diagnoses. Because MPs are heterogeneous in nature, however, further characterization is important be...
- Genotype-Correlated Expression of Lysyl Oxidase-Like 1 in Ocular Tissues of Patients with Pseudoexfoliation Syndrome/Glaucoma and Normal Patients
[作者：Schlotzer-Schrehardt, U; Pasutto, F; Sommer, P; Hornstra, I; Kruse, FE; Naumann, GOH; Reis, A; Zenkel, M,期刊：American Journal of Pathology, 页码：1724-1735 , 文章类型： Article，,卷期：2008年173-6]
- Pseudoexfoliation (PEX) syndrome is a generalized disease of the extracellular matrix and the most common identifiable cause of open-angle glaucoma. Two single nucleotide polymorphisms in the lysyl oxidase-like 1 (LOXL1)...
- Tumors Stimulate Platelet Delivery of Angiogenic Factors in Vivo An Unexpected Benefit
[作者：Pietramaggiori, G; Scherer, SS; Cervi, D; Klelment, G; Orgill, DP,期刊：American Journal of Pathology, 页码：1609-1616 , 文章类型： Article，,卷期：2008年173-6]
- The interaction between platelets and the tumor microenvironment results in the modulation of angiogenesis, although the mechanisms governing this regulation remain unclear. This study explores the differences in the com...
- Deficiency of Immunophilin FKBP52 Promotes Endometriosis
[作者：Hirota, Y; Tranguch, S; Daikoku, T; Hasegawa, A; Osuga, Y; Taketani, Y; Dey, SK,期刊：American Journal of Pathology, 页码：1747-1757 , 文章类型： Article，,卷期：2008年173-6]
- Endometriosis is a common gynecological disease that affects approximately 10% of women of childbearing age. It is characterized by endometrial growth outside the uterus and often results in inflamed lesions, pain, and r...
- MCM7 Interacts with Androgen Receptor
[作者：Shi, YK; Yu, YP; Zhu, ZH; Han, YC; Ren, BG; Nelson, JB; Luo, JH,期刊：American Journal of Pathology, 页码：1758-1767 , 文章类型： Article，,卷期：2008年173-6]
- MCM7 is a critical component of the DNA replication licensing complex that controls DNA replication in both yeast and Xenopus. Our previous studies have indicated that MCM7 is both amplified and overexpressed in metastat...
- Chronic Neuron-Specific Tumor Necrosis Factor-Alpha Expression Enhances the Local Inflammatory Environment Ultimately Leading to Neuronal Death in 3xTg-AD Mice
[作者：Janelsins, MC; Mastrangelo, MA; Park, KM; Sudol, KL; Narrow, WC; Oddo, S; LaFerla, FM; Callahan, LM; Federoff, HJ; Bowers, WJ,期刊：American Journal of Pathology, 页码：1768-1782 , 文章类型： Article，,卷期：2008年173-6]
- Inflammatory mediators, such as tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta, appear integral in initiating and/or propagating Alzheimer's disease (AD)-associated pathogenesis. We have previously observe...
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