- Substituent Effects on the Sensitivity of a Quinoline Photoremovable Protecting Group to One- and Two-Photon Excitation.
[作者:Davis, M. Jarrett;Kragor, Christopher H.;Reddie, Khalilah G.;Wilson, Hunter C.;Zhu, Yue;Dore, Timothy M.;,期刊:Journal of Organic Chemistry, 页码:1721-1729 , 文章类型: 研究论文,,卷期:2009年74-4]
- Photoremovable protecting groups that can reveal biol. important functional groups through one- and two-photon excitation (1PE and 2PE, resp.) have promise in regulating physiol. function in a temporally and spatially re...
- Synthesis and Rearrangement of Quinone-Embedded Epoxycyclopentenones: A New Avenue to Pyranonaphthoquinones and Indenopyranones.
[作者:De, Saroj R.;Ghorai, Sujit K.;Mal, Dipakranjan;,期刊:Journal of Organic Chemistry, 页码:1598-1604 , 文章类型: 研究论文,,卷期:2009年74-4]
- Epoxyquinones (e.g., I), readily assembled in one step from the quinols (e.g., II) by a simplified version of the Dowd oxidn., are shown to undergo rearrangement to pyranonaphthoquinones (e.g., III) and their ring contra...
- Synthesis of Conformationally Preorganized and Cell-Permeable Guanidine-Based g-Peptide Nucleic Acids (gGPNAs).
[作者:Sahu, Bichismita;Chenna, Venugopal;Lathrop, Kira L.;Thomas, Sufi M.;Zon, Gerald;Livak, Kenneth J.;Ly, Danith H.;,期刊:Journal of Organic Chemistry, 页码:1509-1516 , 文章类型: 研究论文,,卷期:2009年74-4]
- A general method for prepg. optically pure guanidine-based g-peptide nucleic acid (gGPNA) monomers for all four natural nucleobases (A, C, G, T) is described. These second-generation gGPNAs differ from the first-generat...
- LiOAc-Catalyzed Chemoselective Deprotection of Aryl Silyl Ethers under Mild Conditions.
[作者:Wang, Bing;Sun, Hui-Xia;Sun, Zhi-Hua;,期刊:Journal of Organic Chemistry, 页码:1781-1784 , 文章类型: 研究论文,,卷期:2009年74-4]
- An efficient and chemoselective deprotection protocol for aryl silyl ethers using LiOAc as a bifunctional Lewis acid-Lewis base catalyst was described. Acetates, epoxides, and aliph. silyl ethers were preserved, whereas...
- A Practical Enantioselective Synthesis of Odanacatib, a Potent Cathepsin K Inhibitor, via Triflate Displacement of an a-Trifluoromethylbenzyl Triflate.
[作者:O'Shea, Paul D.;Chen, Cheng-yi;Gauvreau, Danny;Gosselin, Francis;Hughes, Greg;Nadeau, Christian;Volante, Ralph P.;,期刊:Journal of Organic Chemistry, 页码:1605-1610 , 文章类型: 研究论文,,卷期:2009年74-4]
- An enantioselective synthesis of the Cathepsin K inhibitor odanacatib (I, MK-0822) is described. The key step involves the novel stereospecific SN2 triflate displacement of a chiral a-trifluoromethylbenzyl triflate II w...
- Synthetic Studies toward Sordarin: Building Blocks for the Terpenoid Core and for Analogues Thereof.
[作者:Schule, Arnaud;Liang, Huan;Vors, Jean-Pierre;Ciufolini, Marco A.;,期刊:Journal of Organic Chemistry, 页码:1587-1597 , 文章类型: 研究论文,,卷期:2009年74-4]
- Avenues to bi- and tricyclic building blocks, e.g. I, for the elaboration of sordaricin and its analogs are described. The target mols. were obtained through inter- and intramol. Diels-Alder reactions of a no. of previo...
- Stereochemistry of the C-S Bond Cleavage in cis-2-Methylcyclopentyl Phenyl Sulfoxide Radical Cation.
[作者:Baciocchi, Enrico;Lanzalunga, Osvaldo;Lapi, Andrea;Maggini, Laura;,期刊:Journal of Organic Chemistry, 页码:1805-1808 , 文章类型: 研究论文,,卷期:2009年74-4]
- The TiO2 photocatalyzed oxidn. of cis-2-methylcyclopentyl Ph sulfoxide in the presence of Ag2SO4 in MeCN/H2O leads to the formation of 1-methylcyclopentanol, 1-methylcyclopentylacetamide, and Ph benzenethiosulfonate as t...
- H-Bond-Assisted Regioselective (cis-1) Intramolecular Nucleophilic Addition of the Hydroxyl Group to [60]Fullerene.
[作者:Izquierdo, Marta;Osuna, Silvia;Filippone, Salvatore;Martin-Domenech, Angel;Sola, Miquel;Martin, Nazario;,期刊:Journal of Organic Chemistry, 页码:1480-1487 , 文章类型: 研究论文,,卷期:2009年74-4]
- The one-step reaction of 2,6-dihydroxyphenyl Me ketone and sarcosine with [60]fullerene in refluxing chlorobenzene affords, in a totally regioselective process, the cis-1 bicyclic-fused organofullerene through a new intr...
- Highly regioselective simultaneous introduction of phosphino and seleno groups into unsaturated bonds by the novel combination of (Ph2P)2 and (PhSe)2 upon photoirradiation.
[作者:Kawaguchi, Shin-ichi;Shirai, Takamune;Ohe, Takashi;Nomoto, Akihiro;Sonoda, Motohiro;Ogawa, Akiya;,期刊:Journal of Organic Chemistry, 页码:1751-1754 , 文章类型: 研究论文,,卷期:2009年74-4]
- Prepn. of b-selenoether-functionalized phosphines was achieved by chemoselective radical addn. of (Ph2P)2/(PhSe)2 mixt. to alkenes, alkynes and allenes under UV-irradn. Addn. of (Ph2P)2/(PhSe)2 to RCYCH followed by oxid...
- Diastereoselective Synthesis of Bicyclic g-Lactams via Ring Expansion of Monocyclic b-Lactams.
[作者:Dekeukeleire, Stijn;D'hooghe, Matthias;De Kimpe, Norbert;,期刊:Journal of Organic Chemistry, 页码:1644-1649 , 文章类型: 研究论文,,卷期:2009年74-4]
- Cis-4-(1-Chloro-1-methylethyl)-1-(w-hydroxyalkyl)azetidin-2-ones (I, R = Ph, Bn, Me; n = 1, 2) were diastereoselectively transformed into novel trans-1-aza-4-oxabicyclo[3.3.0]octan-8-ones II (n = 1) and trans-1-aza-5-oxa...
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