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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共7条记录   Recent Developments in the Drug Discovery of Epilepsy [作者：Ahsan, W,期刊：Current Topics in Medicinal Chemistry, 页码：961-961 , 文章类型： Editorial Material，,卷期：2012年12-9] Sodium Channel Blockers as Therapeutic Target for Treating Epilepsy: Recent Updates [作者：Zuliani, V; Fantini, M; Rivara, M,期刊：Current Topics in Medicinal Chemistry, 页码：962-970 , 文章类型： Review，,卷期：2012年12-9] The voltage-gated sodium channels (VGSCs) are a family of membrane proteins forming a pore, through which they selectively conduct sodium ions inward and outward cell's plasma membranes in response to variations of membr... Glutamatergic Neurotransmission As Molecular Target of New Anticonvulsants [作者：Gitto, R; De Luca, L; De Grazia, S; Chimirri, A,期刊：Current Topics in Medicinal Chemistry, 页码：971-993 , 文章类型： Review，,卷期：2012年12-9] Glutamate is the major excitatory neurotransmitter in the mammalian central nervous system (CNS) controlling physiological processes as learning and memory. However, the overactivation of glutamatergic neurotransmission ... Targeting Oxidative Stress Component in the Therapeutics of Epilepsy [作者：Azam, F; Prasad, MVV; Thangavel, N,期刊：Current Topics in Medicinal Chemistry, 页码：994-1007 , 文章类型： Review，,卷期：2012年12-9] The role of free radical-mediated reactions in human neuropathology continues to attract significant interest. Oxidative injury produced by free radicals may play a role in the initiation and progression of epilepsy and,... Genome-Wide Expression Analysis in Epilepsy: A Synthetic Review [作者：Sharma, A,期刊：Current Topics in Medicinal Chemistry, 页码：1008-1032 , 文章类型： Review，,卷期：2012年12-9] Synthesis of genome level expression data related to human epilepsy and animal models of epileptogenesis is a challenge because of differences in the use of animal species and strains, brain regions, methods to trigger e... Recent Progress in Anticonvulsant Drug Research: Strategies for Anticonvulsant Drug Development and Applications of Antiepileptic Drugs for Non-Epileptic Central Nervous System Disorders [作者：Dalkara, S; Karakurt, A,期刊：Current Topics in Medicinal Chemistry, 页码：1033-1071 , 文章类型： Review，,卷期：2012年12-9] Major advances in antiepileptic drug therapy have taken place since 1950s. In the first period, several antiepileptic drugs (AEDs) such as phenobarbital, diphenylhydantoin, ethosuximide, carbamazepine, benzodiazepines an... An Insight into the New Anticonvulsant Agents [作者：Ahsan, W; Safhi, MM; Siddiqui, N; Javed, S; Alam, MS; Azad, B; Akhtar, J,期刊：Current Topics in Medicinal Chemistry, 页码：1072-1092 , 文章类型： Review，,卷期：2012年12-9] The use of current antiepileptic drugs has been questioned due to the nonselectivity of the drugs and the undesirable side effects posed by them. This led to an intensive investigation in this area worldwide during the p...