- Potent and Broad Anti-HIV-1 Activity Exhibited by a Glycosyl-Phosphatidylinositol-Anchored Peptide Derived from the CDR H3 of Broadly Neutralizing Antibody PG16
[作者:Liu, LH; Wen, M; Wang, WM; Wang, SM; Yang, LF; Liu, Y; Qian, MR; Zhang, LQ; Shao, YM; Kimata, JT; Zhou, P,期刊:Journal of virology, 页码:8467-8476 , 文章类型: Article,,卷期:2011年85-17]
- PG9 and PG16 are two recently isolated quaternary-specific human monoclonal antibodies that neutralize 70 to 80% of circulating HIV-1 isolates. The crystal structure of PG16 shows that it contains an exceptionally long C...
- Cutaneous Human Papillomavirus Type 38 E7 Regulates Actin Cytoskeleton Structure for Increasing Cell Proliferation through CK2 and the Eukaryotic Elongation Factor 1A
[作者:Yue, JP; Shukla, R; Accardi, R; Zanella-Cleon, I; Siouda, M; Cros, MP; Krutovskikh, V; Hussain, I; Niu, YM; Hu, SQ; Becchi, M; Jurdic, P; Tommasino, M; Sylla, BS,期刊:Journal of virology, 页码:8477-8494 , 文章类型: Article,,卷期:2011年85-17]
- We previously reported that the oncoproteins E6 and E7 from cutaneous human papillomavirus type 38 (HPV38) can immortalize primary human keratinocytes in vitro and sensitize transgenic mice to develop skin cancer in vivo...
- Functional Genomics Reveals the Induction of Inflammatory Response and Metalloproteinase Gene Expression during Lethal Ebola Virus Infection
[作者:Cilloniz, C; Ebihara, H; Ni, C; Neumann, G; Korth, MJ; Kelly, SM; Kawaoka, Y; Feldmann, H; Katze, MG,期刊:Journal of virology, 页码:9060-9068 , 文章类型: Article,,卷期:2011年85-17]
- Ebola virus is the etiologic agent of a lethal hemorrhagic fever in humans and nonhuman primates with mortality rates of up to 90%. Previous studies with Zaire Ebola virus (ZEBOV), mouse-adapted virus (MA-ZEBOV), and mut...
- The Rhesus Rotavirus Gene Encoding VP4 Is a Major Determinant in the Pathogenesis of Biliary Atresia in Newborn Mice
[作者:Wang, W; Donnelly, B; Bondoc, A; Mohanty, SK; McNeal, M; Ward, R; Sestak, K; Zheng, S; Tiao, G,期刊:Journal of virology, 页码:9069-9077 , 文章类型: Article,,卷期:2011年85-17]
- Biliary atresia (BA) is a devastating disease of childhood for which increasing evidence supports a viral component in pathogenesis. The murine model of BA is induced by perinatal infection with rhesus rotavirus (RRV) bu...
- Epigenetic Silencing of HIV-1 by the Histone H3 Lysine 27 Methyltransferase Enhancer of Zeste 2
[作者:Friedman, J; Cho, WK; Chu, CK; Keedy, KS; Archin, NM; Margolis, DM; Karn, J,期刊:Journal of virology, 页码:9078-9089 , 文章类型: Article,,卷期:2011年85-17]
- Latent HIV proviruses are silenced as the result of deacetylation and methylation of histones located at the viral long terminal repeat (LTR). Inhibition of histone deacetylases (HDACs) leads to the reemergence of HIV-1 ...
- Ebolavirus Delta-Peptide Immunoadhesins Inhibit Marburgvirus and Ebolavirus Cell Entry
[作者:Radoshitzky, SR; Warfield, KL; Chi, XL; Dong, L; Kota, K; Bradfute, SB; Gearhart, JD; Retterer, C; Kranzusch, PJ; Misasi, JN; Hogenbirk, MA; Wahl-Jensen, V; Volchkov, VE; Cunningham, JM; Jahrling, PB; Aman, MJ; Bavari, S; Farzan, M; Kuhn, JH,期刊:Journal of virology, 页码:8502-8513 , 文章类型: Article,,卷期:2011年85-17]
- With the exception of Reston and Lloviu viruses, filoviruses (marburgviruses, ebolaviruses, and "cuevaviruses") cause severe viral hemorrhagic fevers in humans. Filoviruses use a class I fusion protein, GP(1,2), to bind ...
- Phenotypic and Immunologic Comparison of Clade B Transmitted/Founder and Chronic HIV-1 Envelope Glycoproteins
[作者:Wilen, CB; Parrish, NF; Pfaff, JM; Decker, JM; Henning, EA; Haim, H; Petersen, JE; Wojcechowskyj, JA; Sodroski, J; Haynes, BF; Montefiori, DC; Tilton, JC; Shaw, GM; Hahn, BH; Doms, RW,期刊:Journal of virology, 页码:8514-8527 , 文章类型: Article,,卷期:2011年85-17]
- Sexual transmission of human immunodeficiency virus type 1 (HIV-1) across mucosal barriers is responsible for the vast majority of new infections. This relatively inefficient process results in the transmission of a sing...
- Alteration of the Chronic Wasting Disease Species Barrier by In Vitro Prion Amplification
[作者:Kurt, TD; Seelig, DM; Schneider, JR; Johnson, CJ; Telling, GC; Heisey, DM; Hoover, EA,期刊:Journal of virology, 页码:8528-8537 , 文章类型: Article,,卷期:2011年85-17]
- Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) of cervids now detected in 19 states of the United States, three Canadian provinces, and South Korea. Whether noncervid species can be infe...
- The Role of Amino-Terminal Sequences in Cellular Localization and Antiviral Activity of APOBEC3B
[作者:Pak, V; Heidecker, G; Pathak, VK; Derse, D,期刊:Journal of virology, 页码:8538-8547 , 文章类型: Article,,卷期:2011年85-17]
- Human APOBEC3B (A3B) has been described as a potent inhibitor of retroviral infection and retrotransposition. However, we found that the predominantly nuclear A3B only weakly restricted infection by HIV-1, HIV-1 Delta vi...
- Hepatitis C Virus Infection Promotes Hepatic Gluconeogenesis through an NS5A-Mediated, FoxO1-Dependent Pathway
[作者:Deng, L; Shoji, I; Ogawa, W; Kaneda, S; Soga, T; Jiang, D; Ide, YH; Hotta, H,期刊:Journal of virology, 页码:8556-8568 , 文章类型: Article,,卷期:2011年85-17]
- Chronic hepatitis C virus (HCV) infection is often associated with type 2 diabetes. However, the precise mechanism underlying this association is still unclear. Here, using Huh-7.5 cells either harboring HCV-1b RNA repli...
- Comprehensive Proteomic Analysis of Influenza Virus Polymerase Complex Reveals a Novel Association with Mitochondrial Proteins and RNA Polymerase Accessory Factors
[作者:Bradel-Tretheway, BG; Mattiacio, JL; Krasnoselsky, A; Stevenson, C; Purdy, D; Dewhurst, S; Katze, MG,期刊:Journal of virology, 页码:8569-8581 , 文章类型: Article,,卷期:2011年85-17]
- The trimeric RNA polymerase complex (3P, for PA-PB1-PB2) of influenza A virus (IAV) is an important viral determinant of pathogenicity and host range restriction. Specific interactions of the polymerase complex with host...
- Roles of the Fusion and Hemagglutinin-Neuraminidase Proteins in Replication, Tropism, and Pathogenicity of Avian Paramyxoviruses
[作者:Kim, SH; Subbiah, M; Samuel, AS; Collins, PL; Samal, SK,期刊:Journal of virology, 页码:8582-8596 , 文章类型: Article,,卷期:2011年85-17]
- Virulent and moderately virulent strains of Newcastle disease virus (NDV), representing avian paramyxovirus serotype 1 (APMV-1), cause respiratory and neurological disease in chickens and other species of birds. In contr...
- Campylobacter jejuni Group III Phage CP81 Contains Many T4-Like Genes without Belonging to the T4-Type Phage Group: Implications for the Evolution of T4 Phages
[作者:Hammerl, JA; Jackel, C; Reetz, J; Beck, S; Alter, T; Lurz, R; Barretto, C; Brussow, H; Hertwig, S,期刊:Journal of virology, 页码:8597-8605 , 文章类型: Article,,卷期:2011年85-17]
- CP81 is a virulent Campylobacter group III phage whose linear genome comprises 132,454 bp. At the nucleotide level, CP81 differs from other phages. However, a number of its structural and replication/recombination protei...
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