- Enzyme E2 from Chinese White Shrimp Inhibits Replication of White Spot Syndrome Virus and Ubiquitinates Its RING Domain Proteins
[作者:Chen, AJ; Wang, SA; Zhao, XF; Yu, XQ; Wang, JX,期刊:Journal of virology, 页码:8069-8079 , 文章类型: Article,,卷期:2011年85-16]
- Recent studies have shown that the ubiquitin (Ub) proteasome pathway (UPP) is closely related to immune defense. We have identified a ubiquitin-conjugating enzyme, E2, from the Chinese white shrimp, Fenneropenaeus chinen...
- Influenza A Virus N5 Neuraminidase Has an Extended 150-Cavity
[作者:Wang, MY; Qi, JX; Liu, Y; Vavricka, CJ; Wu, Y; Li, Q; Gao, GF,期刊:Journal of virology, 页码:8431-8435 , 文章类型: Article,,卷期:2011年85-16]
- There are 9 serotypes of neuraminidase (NA) from influenza A virus (N1 to N9), which are classified into two groups based on primary sequences (groups 1 and 2). The structural hallmark of the two groups is the presence o...
- Cytoplasmic Domain of Marburg Virus GP Modulates Early Steps of Viral Infection
[作者:Mittler, E; Kolesnikova, L; Hartlieb, B; Davey, R; Becker, S,期刊:Journal of virology, 页码:8188-8196 , 文章类型: Article,,卷期:2011年85-16]
- Marburg virus infection is mediated by the only viral surface protein, GP, a trimeric type I transmembrane protein. While its ectodomain mediates receptor binding and fusion of viral and cellular membranes and its transm...
- Evolution of Human Immunodeficiency Virus Type 1 in a Patient with Cross-Reactive Neutralizing Activity in Serum
[作者:van Gils, MJ; Edo-Matas, D; Bowles, EJ; Burger, JA; Stewart-Jones, GB; Schuitemaker, H,期刊:Journal of virology, 页码:8443-8448 , 文章类型: Article,,卷期:2011年85-16]
- Analysis of longitudinally obtained HIV-1 env sequences from an individual with reported cross-reactive neutralizing activity revealed that the majority of viral variants obtained from serum between 4 and 7 years after s...
- Characterization of Glycosylation Profiles of HIV-1 Transmitted/Founder Envelopes by Mass Spectrometry
[作者:Go, EP; Hewawasam, G; Liao, HX; Chen, HY; Ping, LH; Anderson, JA; Hua, DC; Haynes, BF; Desaire, H,期刊:Journal of virology, 页码:8270-8284 , 文章类型: Article,,卷期:2011年85-16]
- The analysis of HIV-1 envelope carbohydrates is critical to understanding their roles in HIV-1 transmission as well as in binding of envelope to HIV-1 antibodies. However, direct analysis of protein glycosylation by glyc...
- Detection of Minority Resistance during Early HIV-1 Infection: Natural Variation and Spurious Detection rather than Transmission and Evolution of Multiple Viral Variants
[作者:Gianella, S; Delport, W; Pacold, ME; Young, JA; Choi, JY; Little, SJ; Richman, DD; Pond, SLK; Smith, DM,期刊:Journal of virology, 页码:8359-8367 , 文章类型: Article,,卷期:2011年85-16]
- Reports of a high frequency of the transmission of minority viral populations with drug-resistant mutations (DRM) are inconsistent with evidence that HIV-1 infections usually arise from mono-or oligoclonal transmission. ...
- Expression and Functional Characterization of the RIG-I-Like Receptors MDA5 and LGP2 in Rainbow Trout (Oncorhynchus mykiss)
[作者:Chang, MX; Collet, B; Nie, P; Lester, K; Campbell, S; Secombes, CJ; Zou, J,期刊:Journal of virology, 页码:8403-8412 , 文章类型: Article,,卷期:2011年85-16]
- The retinoic acid-inducible gene I (RIG-I)-like receptors (RLR) comprise three homologues: RIG-I, melanoma differentiation-associated gene 5 (MDA5), and laboratory of genetics and physiology 2 (LGP2). They activate the h...
- Human Dendritic Cells Infected with the Nonpathogenic Mopeia Virus Induce Stronger T-Cell Responses than Those Infected with Lassa Virus
[作者:Pannetier, D; Reynard, S; Russier, M; Journeaux, A; Tordo, N; Deubel, V; Baize, S,期刊:Journal of virology, 页码:8293-8306 , 文章类型: Article,,卷期:2011年85-16]
- The events leading to death in severe cases of Lassa fever (LF) are unknown. Fatality seems to be linked to high viremia and immunosuppression, and cellular immunity, rather than neutralizing antibodies, appears to be es...
- Inhibition of p53 by Adenovirus Type 12 E1B-55K Deregulates Cell Cycle Control and Sensitizes Tumor Cells to Genotoxic Agents
[作者:Li, Q; Zhao, LY; Zheng, Z; Yang, H; Santiago, A; Liao, DQ,期刊:Journal of virology, 页码:7976-7988 , 文章类型: Article,,卷期:2011年85-16]
- Adenovirus E1B-55K represses p53-mediated transcription. However, the phenotypic consequence of p53 inhibition by E1B-55K for cell cycle regulation and drug sensitivity in tumor cells has not been examined. In HCT116 cel...
- Inhibitory Effect of a Nucleotide Analog on Infectious Salmon Anemia Virus Infection
[作者:Rivas-Aravena, A; Vallejos-Vidal, E; Cortez-San Martin, M; Reyes-Lopez, F; Tello, M; Mora, P; Sandino, AM; Spencer, E,期刊:Journal of virology, 页码:8037-8045 , 文章类型: Article,,卷期:2011年85-16]
- The infectious salmon anemia virus (ISAV), which belongs to the Orthomyxoviridae family, has been responsible for major losses in the salmon industry, with mortalities close to 100% in areas where Atlantic salmon (Salmo ...
- Multiple CCR5 Conformations on the Cell Surface Are Used Differentially by Human Immunodeficiency Viruses Resistant or Sensitive to CCR5 Inhibitors
[作者:Berro, R; Klasse, PJ; Lascano, D; Flegler, A; Nagashima, KA; Sanders, RW; Sakmar, TP; Hope, TJ; Moore, JP,期刊:Journal of virology, 页码:8227-8240 , 文章类型: Article,,卷期:2011年85-16]
- Resistance to small-molecule CCR5 inhibitors arises when HIV-1 variants acquire the ability to use inhibitor-bound CCR5 while still recognizing free CCR5. Two isolates, CC101.19 and D1/85.16, became resistant via four su...
- Mx Is Dispensable for Interferon-Mediated Resistance of Chicken Cells against Influenza A Virus
[作者:Schusser, B; Reuter, A; von der Malsburg, A; Penski, N; Weigend, S; Kaspers, B; Staeheli, P; Hartle, S,期刊:Journal of virology, 页码:8307-8315 , 文章类型: Article,,卷期:2011年85-16]
- The type I interferon (IFN) system plays an important role in antiviral defense against influenza A viruses (FLUAV), which are natural chicken pathogens. Studies of mice identified the Mx1 protein as a key effector molec...
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