- Structure, Formation and Propagation of Amyloid Fibrils
[作者:Goto, Y; Yagi, H; Yamaguchi, K; Chatani, E; Ban, T,期刊:Current Pharmaceutical Design, 页码:3205-3218 , 文章类型: Review,,卷期:2008年14-30]
- Amyloid fibrils have been a critical subject in recent studies of proteins since they are associated with the pathology of more than 20 serious human diseases. Moreover, a variety of proteins and peptides not related to ...
- Amyloid beta-Protein Assembly as a Therapeutic Target of Alzheimer's Disease
[作者:Yamin, G; Ono, K; Inayathullah, M; Teplow, DB,期刊:Current Pharmaceutical Design, 页码:3231-3246 , 文章类型: Review,,卷期:2008年14-30]
- Alzheimer's disease (AD), the most common neurodegenerative disorder in the aged, is characterized by the cerebral deposition of fibrils formed by the amyloid beta-protein (A beta), a 40-42 amino acid peptide. The foldin...
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