- Hypersensitivity Reactions to Neuromuscular Blocking Agents
[作者：Mertes, PM; Aimone-Gastin, I; Gueant-Rodriguez, RM; Mouton-Faivre, C; Audibert, G; O'Brien, J; Frendt, D; Brezeanu, M; Bouaziz, H; Gueant, JL,期刊：Current Pharmaceutical Design, 页码：2809-2825 , 文章类型： Review，,卷期：2008年14-27]
- Neuromuscular blocking agents are the leading drugs responsible for immediate hypersensitivity reactions during anaesthesia. Most hypersensitivity reactions represent IgE-mediated allergic reactions. Their incidence is e...
- Pharmacogenetic Determinants of Immediate and Delayed Reactions of Drug Hypersensitivity
[作者：Gueant, JL; Gueant-Rodriguez, RM; Gastin, IA; Cornejo-Garcia, JA; Viola, M; Barbaud, A; Mertes, PM; Blanca, M; Romano, A,期刊：Current Pharmaceutical Design, 页码：2770-2777 , 文章类型： Review，,卷期：2008年14-27]
- Drug allergy refers to a hypersensitivity reaction for which either an IgE or T-cell-mediated mechanism is demonstrated. The recognition of the drug by B and T cells is influenced by variants of HLA genes. The genetic fa...
- Provocation Tests in Diagnosing Drug Hypersensitivity
[作者：Bousquet, PJ; Gaeta, F; Bousquet-Rouanet, L; Lefrant, JY; Demoly, P; Romano, A,期刊：Current Pharmaceutical Design, 页码：2792-2802 , 文章类型： Review，,卷期：2008年14-27]
- A position paper by the European Network for Drug Allergy (ENDA), the European Academy of Allergology and Clinical Immunology (EAACI) interest group on drug hypersensitivity, defines drug provocation tests (DPTs) as "the...
- Cross-Reactive Reactions to Nonsteroidal Anti-Inflammatory Drugs
[作者：Viola, M; Quaratino, D; Gaeta, F; Rumi, G; Caruso, C; Romano, A,期刊：Current Pharmaceutical Design, 页码：2826-2832 , 文章类型： Review，,卷期：2008年14-27]
- Introduction: Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most frequent causes of adverse drug reactions, particularly in patients with asthma and chronic idiophatic urticaria. Many subjects report cutane...
- Allergic and Photoallergic Contact Dermatitis from Ketoprofen: Evaluation of Cross-Reactivities by a Combination of Photopatch Testing and Computerized Conformational Analysis
[作者：Foti, C; Bonamonte, D; Conserva, A; Stingeni, L; Lisi, P; Lionetti, N; Rigano, L; Angelini, G,期刊：Current Pharmaceutical Design, 页码：2833-2839 , 文章类型： Review，,卷期：2008年14-27]
- Allergic contact dermatitis (ACD) and photo-ACD are cell-mediated delayed hypersensitivity reactions of the skin caused by a wide range of substances. Topical ketoprofen (KP), a nonsteroidal anti-inflammatory drug (NSAID...
- Macrolides Allergy
[作者：Araujo, L; Demoly, P,期刊：Current Pharmaceutical Design, 页码：2840-2862 , 文章类型： Review，,卷期：2008年14-27]
- Macrolides are characterised by their basic structure which is made up of a lactonic cycle with 2 osidic chains. They are classified according to the number of carbon atoms in the cycle : 14 membered macrolides (erythrom...
- Hypersensitivity Reactions to Anticoagulant Drugs
[作者：Scherer, K; Tsakiris, DA; Bircher, AJ,期刊：Current Pharmaceutical Design, 页码：2863-2873 , 文章类型： Review，,卷期：2008年14-27]
- Drugs with anticoagulant activity, including heparins, hirudins, coumarins, and platelet aggregation inhibitors belong to the most widely used drugs. Hypersensitivity reactions from these agents are rare. However, due to...
- Hypersensitivity to Lamotrigine and Nonaromatic Anticonvulsant Drugs: A Review
[作者：Gaeta, F; Alonzi, C; Valluzzi, RL; Viola, M; Elia, M; Romano, A,期刊：Current Pharmaceutical Design, 页码：2874-2882 , 文章类型： Review，,卷期：2008年14-27]
- Lamotrigine and nonaromatic antiepileptic drugs (valproate, gabapentin, and topiramate) are associated with hypersensitivity reactions, mainly cutaneous eruptions. The underlying mechanisms of these manifestations are no...
- Hypersensitivity Reactions to Last Generation Chimeric, Umanized and Human Recombinant Monoclonal Antibodies for Therapeutic Use
[作者：Calogiuri, G; Ventura, MT; Mason, L; Valacca, A; Buquicchio, R; Cassano, N; Vena, GA,期刊：Current Pharmaceutical Design, 页码：2883-2891 , 文章类型： Review，,卷期：2008年14-27]
- A new class of drugs, produced with the hybridoma technique, has been introduced and employed to treat many immunological diseases. This class consists of recombinant monoclonal antibodies, which can be chimeric, humaniz...
- Antiinflammatory Effects of H1-Antihistamines: Clinical and Immunological Relevance
[作者：Vena, GA; Cassano, N; Buquicchio, R; Ventura, MT,期刊：Current Pharmaceutical Design, 页码：2902-2911 , 文章类型： Review，,卷期：2008年14-27]
- Signs supporting antiinflammatory effects of H1-antihistamines were first reported long ago, but their clinical relevance remains controversial, especially with respect to their ability to inhibit the release of histamin...
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