- Determinants of brain iron in multiple sclerosis A quantitative 3T MRI study
[作者:Khalil, M; Langkammer, C; Ropele, S; Petrovic, K; Wallner-Blazek, M; Loitfelder, M; Jehna, M; Bachmaier, G; Schmidt, R; Enzinger, C; Fuchs, S; Fazekas, F,期刊:Neurology, 页码:1691-1697 , 文章类型: Article,,卷期:2011年77-18]
- Objectives: Abnormal high cerebral iron deposition may be implicated in chronic neurologic disorders, including multiple sclerosis (MS). R2* relaxometry has been recently validated in a postmortem study to indicate brain...
- Antibodies to metabotropic glutamate receptor 5 in the Ophelia syndrome
[作者:Lancaster, E; Martinez-Hernandez, E; Titulaer, MJ; Boulos, M; Weaver, S; Antoine, JC; Liebers, E; Kornblum, C; Bien, CG; Honnorat, J; Wong, S; Xu, J; Contractor, A; Balice-Gordon, R; Dalmau, J,期刊:Neurology, 页码:1698-1701 , 文章类型: Article,,卷期:2011年77-18]
- Objective: To report the metabotropic glutamate receptor 5 (mGluR5) as the autoantigen of antibodies from 2 patients with Hodgkin lymphoma (HL) and limbic encephalopathy (Ophelia syndrome).Methods: Immunohistochemistry w...
- PRION-1 scales analysis supports use of functional outcome measures in prion disease
[作者:Mead, S; Ranopa, M; Gopalakrishnan, GS; Thompson, AGB; Rudge, P; Wroe, S; Kennedy, A; Hudson, F; MacKay, A; Darbyshire, JH; Collinge, J; Walker, AS,期刊:Neurology, 页码:1674-1683 , 文章类型: Article,,卷期:2011年77-18]
- Objectives: Human prion diseases are heterogeneous but invariably fatal neurodegenerative disorders with no known effective therapy. PRION-1, the largest clinical trial in prion disease to date, showed no effect of the p...
- Combined MRI lesions and relapses as a surrogate for disability in multiple sclerosis
[作者:Sormani, MP; Li, DK; Bruzzi, P; Stubinski, B; Cornelisse, P; Rocak, S; De Stefano, N,期刊:Neurology, 页码:1684-1690 , 文章类型: Article,,卷期:2011年77-18]
- Objective: In multiple sclerosis (MS), the aim of therapies is to prevent the accumulation of irreversible disability. This is difficult to assess given the short time course of clinical trials. MRI markers and relapses ...
- Care and outcomes in patients with ischemic stroke with and without preexisting dementia
[作者:Saposnik, G; Cote, R; Rochon, PA; Mamdani, M; Liu, Y; Raptis, S; Kapral, MK; Black, SE,期刊:Neurology, 页码:1664-1673 , 文章类型: Article,,卷期:2011年77-18]
- Objective: To describe clinical characteristics and evaluate processes of care and outcomes at discharge in patients with ischemic stroke with and without preexisting dementia.Methods: Retrospective cohort study using th...
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