- Regulation of podosome dynamics by WASp phosphorylation: implication in matrix degradation and chemotaxis in macrophages
[作者:Dovas, A; Gevrey, JC; Grossi, A; Park, H; Abou-Kheir, W; Cox, D,期刊:Journal of cell science, 页码:3873-3882 , 文章类型: Article,,卷期:2009年122-21]
- Podosomes, adhesion structures capable of matrix degradation, have been linked with the ability of cells to perform chemotaxis and invade tissues. Wiskott-Aldrich Syndrome protein (WASp), an effector of the RhoGTPase Cdc...
- Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101
[作者:Leithe, E; Kjenseth, A; Sirnes, S; Stenmark, H; Brech, A; Rivedal, E,期刊:Journal of cell science, 页码:3883-3893 , 文章类型: Article,,卷期:2009年122-21]
- Gap junctions are dynamic plasma membrane domains, and their protein constituents, the connexins, have a high turnover rate in most tissue types. However, the molecular mechanisms involved in degradation of gap junctions...
- Real-time measurements of cAMP production in live Dictyostelium cells
[作者:Bagorda, A; Das, S; Rericha, EC; Chen, D; Davidson, J; Parent, CA,期刊:Journal of cell science, 页码:3907-3914 , 文章类型: Article,,卷期:2009年122-21]
- Cyclic AMP has a crucial role during the entire developmental program of the social amoebae Dictyostelium, acting both as an intracellular second messenger and, when secreted, as a directional cue that is relayed to neig...
- Myosin-Va restrains the trafficking of Na+/K+-ATPase-containing vesicles in alveolar epithelial cells
[作者:Lecuona, E; Minin, A; Trejo, HE; Chen, JW; Comellas, AP; Sun, HY; Grillo, D; Nekrasova, OE; Welch, LC; Szleifer, I; Gelfand, VI; Sznajder, JI,期刊:Journal of cell science, 页码:3915-3922 , 文章类型: Article,,卷期:2009年122-21]
- Stimulation of Na+/K+-ATPase activity in alveolar epithelial cells by cAMP involves its recruitment from intracellular compartments to the plasma membrane. Here, we studied the role of the actin molecular motor myosin-V ...
- Identification of targets of Prox1 during in vitro vascular differentiation from embryonic stem cells: functional roles of HoxD8 in lymphangiogenesis
[作者:Harada, K; Yamazaki, T; Iwata, C; Yoshimatsu, Y; Sase, H; Mishima, K; Morishita, Y; Hirashima, M; Oike, Y; Suda, T; Miura, N; Watabe, T; Miyazono, K,期刊:Journal of cell science, 页码:3923-3930 , 文章类型: Article,,卷期:2009年122-21]
- During lymphatic development, Prox1 plays central roles in the differentiation of blood vascular endothelial cells (BECs) into lymphatic endothelial cells (LECs), and subsequently in the maturation and maintenance of lym...
- Nuclear localisation is crucial for the proapoptotic activity of the HtrA-like serine protease Nma111p
[作者:Belanger, KD; Walter, D; Henderson, TA; Yelton, AL; O'Brien, TG; Belanger, KG; Geier, SJ; Fahrenkrog, B,期刊:Journal of cell science, 页码:3931-3941 , 文章类型: Article,,卷期:2009年122-21]
- Programmed cell death is induced by the activation of a subset of intracellular proteins in response to specific extra- and intracellular signals. In the yeast Saccharomyces cerevisiae, Nma111p functions as a nuclear ser...
- Differential VASP phosphorylation controls remodeling of the actin cytoskeleton
[作者:Benz, PM; Blume, C; Seifert, S; Wilhelm, S; Waschke, J; Schuh, K; Gertler, F; Munzel, T; Renne, T,期刊:Journal of cell science, 页码:3954-3965 , 文章类型: Article,,卷期:2009年122-21]
- Proteins of the Enabled/vasodilator-stimulated phosphoprotein (Ena/VASP) family link signal transduction pathways to actin cytoskeleton dynamics. VASP is substrate of cAMP-dependent, cGMP-dependent and AMP-activated prot...
- The transmembrane protein CBP plays a role in transiently anchoring small clusters of Thy-1, a GPI-anchored protein, to the cytoskeleton
[作者:Chen, Y; Veracini, L; Benistant, C; Jacobson, K,期刊:Journal of cell science, 页码:3966-3972 , 文章类型: Article,,卷期:2009年122-21]
- It remains unclear how GPI-anchored proteins (GPIAPs), which lack cytoplasmic domains, transduce signals triggered by specific ligation. Such signal transduction has been speculated to require the ligated GPIAP to associ...
- p53-dependent control of transactivation of the Pen2 promoter by presenilins
[作者:Dunys, J; Sevalle, J; Giaime, E; Pardossi-Piquard, R; Vitek, MP; Renbaum, P; Levy-Lahad, E; Zhang, YW; Xu, HX; Checler, F; da Costa, CA,期刊:Journal of cell science, 页码:4003-4008 , 文章类型: Article,,卷期:2009年122-21]
- The senile plaques found in the brains of patients with Alzheimer's disease are mainly due to the accumulation of amyloid beta-peptides (A beta) that are liberated by gamma-secretase, a high molecular weight complex incl...
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