- Mammalian macroautophagy at a glance
[作者:Ravikumar, B; Futter, M; Jahreiss, L; Korolchuk, VI; Lichtenberg, M; Luo, S; Massey, DCO; Menzies, FM; Narayanan, U; Renna, M; Jimenez-Sanchez, M; Sarkar, S; Underwood, B; Winslow, A; Rubinsztein, DC,期刊:Journal of cell science, 页码:1707-1711 , 文章类型: Article,,卷期:2009年122-11]
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- Roles of the Drosophila NudE protein in kinetochore function and centrosome migration
[作者:Wainman, A; Creque, J; Williams, B; Williams, EV; Bonaccorsi, S; Gatti, M; Goldberg, ML,期刊:Journal of cell science, 页码:1747-1758 , 文章类型: Article,,卷期:2009年122-11]
- We examined the distribution of the dynein-associated protein NudE in Drosophila larval brain neuroblasts and spermatocytes, and analyzed the phenotypic consequences of a nudE null mutation. NudE can associate with kinet...
- alpha 3 beta 1 integrin in epidermis promotes wound angiogenesis and keratinocyte-to-endothelial-cell crosstalk through the induction of MRP3
[作者:Mitchell, K; Szekeres, C; Milano, V; Svenson, KB; Nilsen-Hamilton, M; Kreidberg, JA; DiPersio, CM,期刊:Journal of cell science, 页码:1778-1787 , 文章类型: Article,,卷期:2009年122-11]
- During cutaneous wound healing, epidermal keratinocytes play essential roles in the secretion of factors that promote angiogenesis. However, specific cues in the wound microenvironment that trigger the production of pro-...
- Increased invasive behaviour in cutaneous squamous cell carcinoma with loss of basement-membrane type VII collagen
[作者:Martins, VL; Vyas, JJ; Chen, M; Purdie, K; Mein, CA; South, AP; Storey, A; McGrath, JA; O'Toole, EA,期刊:Journal of cell science, 页码:1788-1799 , 文章类型: Article,,卷期:2009年122-11]
- Type VII collagen (ColVII) is the main component of anchoring fibrils, attachment structures within the lamina densa of the basement membrane that are responsible for attachment of the epidermis to the dermis in skin. Mu...
- Molecular dissection of the ILK-PINCH-parvin triad reveals a fundamental role for the ILK kinase domain in the late stages of focal-adhesion maturation
[作者:Stanchi, F; Grashoff, C; Yonga, CFN; Grall, D; Fassler, R; Van Obberghen-Schilling, E,期刊:Journal of cell science, 页码:1800-1811 , 文章类型: Article,,卷期:2009年122-11]
- Integrin-linked kinase (ILK) and cytoplasmic adaptors of the PINCH and parvin families form a ternary complex, termed IPP, that localizes to integrin adhesions. We show here that deletion of the genes encoding ILK or PIN...
- Formation of endothelial lumens requires a coordinated PKC epsilon-, Src-, Pak- and Raf-kinase-dependent signaling cascade downstream of Cdc42 activation
[作者:Koh, W; Sachidanandam, K; Stratman, AN; Sacharidou, A; Mayo, AM; Murphy, EA; Cheresh, DA; Davis, GE,期刊:Journal of cell science, 页码:1812-1822 , 文章类型: Article,,卷期:2009年122-11]
- In this study, we present data showing that Cdc42-dependent lumen formation by endothelial cells (ECs) in three-dimensional (3D) collagen matrices involves coordinated signaling by PKCe epsilon in conjunction with the Sr...
- Loss of dioxin-receptor expression accelerates wound healing in vivo by a mechanism involving TGF beta
[作者:Carvajal-Gonzalez, JM; Roman, AC; Cerezo-Guisado, MI; Rico-Leo, EM; Martin-Partido, G; Fernandez-Salguero, PM,期刊:Journal of cell science, 页码:1823-1833 , 文章类型: Article,,卷期:2009年122-11]
- Delayed wound healing caused by inefficient re-epithelialization underlines chronic skin lesions such as those found in diabetes. The dioxin receptor (AhR) modulates cell plasticity and migration and its activation by oc...
- Coatomer-dependent protein delivery to lipid droplets
[作者:Soni, KG; Mardones, GA; Sougrat, R; Smirnova, E; Jackson, CL; Bonifacino, JS,期刊:Journal of cell science, 页码:1834-1841 , 文章类型: Article,,卷期:2009年122-11]
- Lipid droplets (LDs) are cytoplasmic organelles that store neutral lipids for use as an energy supply in times of nutrient deprivation and for membrane assembly. Misregulation of LD function leads to many human diseases,...
- beta 8 integrin regulates neurogenesis and neurovascular homeostasis in the adult brain
[作者:Mobley, AK; Tchaicha, JH; Shin, J; Hossain, MG; McCarty, JH,期刊:Journal of cell science, 页码:1842-1851 , 文章类型: Article,,卷期:2009年122-11]
- Central nervous system (CNS) neurovascular units are multicellular complexes consisting of neural cells, blood vessels and a milieu of extracellular matrix (ECM) proteins. ECM-mediated adhesion and signaling events withi...
- Inhibitors of clathrin-dependent endocytosis enhance TGF beta signaling and responses
[作者:Chen, CL; Hou, WH; Liu, IH; Hsiao, G; Huang, SS; Huang, JS,期刊:Journal of cell science, 页码:1863-1871 , 文章类型: Article,,卷期:2009年122-11]
- Clathrin-dependent endocytosis is believed to be involved in TGF beta-stimulated cellular responses, but the subcellular locus at which TGF beta induces signaling remains unclear. Here, we demonstrate that inhibitors of ...
- Cajal-body formation correlates with differential coilin phosphorylation in primary and transformed cell lines
[作者:Hearst, SM; Gilder, AS; Negi, SS; Davis, MD; George, EM; Whittom, AA; Toyota, CG; Husedzinovic, A; Gruss, OJ; Hebert, MD,期刊:Journal of cell science, 页码:1872-1881 , 文章类型: Article,,卷期:2009年122-11]
- Cajal bodies (CBs) are nuclear structures that are thought to have diverse functions, including small nuclear ribonucleoprotein (snRNP) biogenesis. The phosphorylation status of coilin, the CB marker protein, might impac...
- VASP is a CXCR2-interacting protein that regulates CXCR2-mediated polarization and chemotaxis
[作者:Neel, NF; Barzik, M; Raman, D; Sobolik-Delmaire, T; Sai, J; Ham, AJ; Mernaugh, RL; Gertler, FB; Richmond, A,期刊:Journal of cell science, 页码:1882-1894 , 文章类型: Article,,卷期:2009年122-11]
- Chemotaxis regulates the recruitment of leukocytes, which is integral for a number of biological processes and is mediated through the interaction of chemokines with seven transmembrane G-protein-coupled receptors. Sever...
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