- Splicing of HDAC7 modulates the SRF-myocardin complex during stem-cell differentiation towards smooth muscle cells
[作者:Margariti, A; Xiao, QZ; Zampetaki, A; Zhang, ZY; Li, HL; Martin, D; Hu, YH; Zeng, LF; Xu, QB,期刊:Journal of cell science, 页码:460-470 , 文章类型: Article,,卷期:2009年122-4]
- Histone deacetylases (HDACs) have a central role in the regulation of gene expression. Here we investigated whether HDAC7 has an impact on embryonic stem (ES) cell differentiation into smooth muscle cells (SMCs). ES cell...
- Drosophila Past1 is involved in endocytosis and is required for germline development and survival of the adult fly
[作者:Olswang-Kutz, Y; Gertel, Y; Benjamin, S; Sela, O; Pekar, O; Arama, E; Steller, H; Horowitz, M; Segal, D,期刊:Journal of cell science, 页码:471-480 , 文章类型: Article,,卷期:2009年122-4]
- Endocytosis, which is a key process in eukaryotic cells, has a central role in maintaining cellular homeostasis, nutrient uptake, development and downregulation of signal transduction. This complex process depends on sev...
- Functional suppression of E-cadherin by protein kinase C delta
[作者:Chen, CL; Chen, HC,期刊:Journal of cell science, 页码:513-523 , 文章类型: Article,,卷期:2009年122-4]
- Protein kinase C (PKC) delta, a member of the novel PKC subfamily, has been shown to have an important role in cell proliferation, differentiation, apoptosis and cell motility. In this study, we investigated the effect o...
- Drebrin A regulates dendritic spine plasticity and synaptic function in mature cultured hippocampal neurons
[作者:Ivanov, A; Esclapez, M; Pellegrino, C; Shirao, T; Ferhat, L,期刊:Journal of cell science, 页码:524-534 , 文章类型: Article,,卷期:2009年122-4]
- Drebrin A, one of the most abundant neuron-specific F-actinbinding proteins, is found exclusively in dendrites and is particularly concentrated in dendritic spines receiving excitatory inputs. We investigated the role of...
- Mars, a Drosophila protein related to vertebrate HURP, is required for the attachment of centrosomes to the mitotic spindle during syncytial nuclear divisions
[作者:Zhang, G; Breuer, M; Forster, A; Egger-Adam, D; Wodarz, A,期刊:Journal of cell science, 页码:535-545 , 文章类型: Article,,卷期:2009年122-4]
- The formation of the mitotic spindle is controlled by the microtubule organizing activity of the centrosomes and by the effects of chromatin-associated Ran-GTP on the activities of spindle assembly factors. In this study...
- Mechanically induced osteogenic differentiation - the role of RhoA, ROCKII and cytoskeletal dynamics
[作者:Arnsdorf, EJ; Tummala, P; Kwon, RY; Jacobs, CR,期刊:Journal of cell science, 页码:546-553 , 文章类型: Article,,卷期:2009年122-4]
- Many biochemical factors regulating progenitor cell differentiation have been examined in detail; however, the role of the local mechanical environment on stem cell fate has only recently been investigated. In this study...
- Cx43 has distinct mobility within plasma-membrane domains, indicative of progressive formation of gap-junction plaques
[作者:Simek, J; Churko, J; Shao, Q; Laird, DW,期刊:Journal of cell science, 页码:554-562 , 文章类型: Article,,卷期:2009年122-4]
- Connexin 43 (Cx43) is a dynamic molecule, having a short half-life of only a few hours. In this study, we use fluorescent-protein-tagged Cx43 variants to examine Cx43 delivery to the cell surface, its residency status in...
- Induced early expression of mrf4 but not myog rescues myogenesis in the myod/myf5 double-morphant zebrafish embryo
[作者:Schnapp, E; Pistocchi, AS; Karampetsou, E; Foglia, E; Lamia, CL; Cotelli, F; Cossu, G,期刊:Journal of cell science, 页码:481-488 , 文章类型: Article,,卷期:2009年122-4]
- Muscle regulatory factors activate myogenesis in all vertebrates, but their role has been studied in great detail only in the mouse embryo, where all but myogenin - Myod, Myf5 and Mrf4 - are sufficient to activate (albei...
- Involvement of SIRT7 in resumption of rDNA transcription at the exit from mitosis
[作者:Grob, A; Roussel, P; Wright, JE; McStay, B; Hernandez-Verdun, D; Sirri, V,期刊:Journal of cell science, 页码:489-498 , 文章类型: Article,,卷期:2009年122-4]
- Sirtuins, also designated class III histone deacetylases, are implicated in the regulation of cell division, apoptosis, DNA damage repair, genomic silencing and longevity. The nucleolar Sirtuin7 (SIRT7) was reported to b...
- Lipids regulate P2X7-receptor-dependent actin assembly by phagosomes via ADP translocation and ATP synthesis in the phagosome lumen
[作者:Kuehnel, MP; Rybin, V; Anand, PK; Anes, E; Griffiths, G,期刊:Journal of cell science, 页码:499-504 , 文章类型: Article,,卷期:2009年122-4]
- Latex bead phagosomes isolated from J774 macrophages polymerize actin. We show here that five lipids phosphatidylinositol-4-phosphate, phosphatidylinositol-(4,5)bisphosphate, sphingosine-1-phosphate (S1P), ceramide-1-pho...
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