- An integral protein of the inner nuclear membrane localizes to the mitotic spindle in mammalian cells
[作者:Buch, C; Lindberg, R; Figueroa, R; Gudise, S; Onischenko, E; Hallberg, E,期刊:Journal of cell science, 页码:2100-2107 , 文章类型: Article,,卷期:2009年122-12]
- Here, we characterize a transmembrane protein of the nuclear envelope that we name spindle-associated membrane protein 1 (Samp1). The protein is conserved in metazoa and fission yeast and is homologous to Net5 in rat and...
- EFA6A encodes two isoforms with distinct biological activities in neuronal cells
[作者:Sironi, C; Teesalu, T; Muggia, A; Fontana, G; Marino, F; Savaresi, S; Talarico, D,期刊:Journal of cell science, 页码:2108-2118 , 文章类型: Article,,卷期:2009年122-12]
- The processes of neurite extension and remodeling require a close coordination between the cytoskeleton and the cell membranes. The small GTPase ARF6 (ADP-ribosylation factor 6) has a central role in regulating membrane ...
- Contractility-dependent actin dynamics in cardiomyocyte sarcomeres
[作者:Skwarek-Maruszewska, A; Hotulainen, P; Mattila, PK; Lappalainen, P,期刊:Journal of cell science, 页码:2119-2126 , 文章类型: Article,,卷期:2009年122-12]
- In contrast to the highly dynamic actin cytoskeleton in nonmuscle cells, actin filaments in muscle sarcomeres are thought to be relatively stable and undergo dynamics only at their ends. However, many proteins that promo...
- Rac3 inhibits adhesion and differentiation of neuronal cells by modifying GIT1 downstream signaling
[作者:Hajdo-Milasinovic, A; van der Kammen, RA; Moneva, Z; Collard, JG,期刊:Journal of cell science, 页码:2127-2136 , 文章类型: Article,,卷期:2009年122-12]
- Rac1 and Rac3 are highly homologous regulatory proteins that belong to the small GTPases of the Rho family. Previously, we showed that Rac3 induces cell rounding and prevents neuronal differentiation, in contrast to its ...
- A novel genetic mechanism regulates dorsolateral hinge-point formation during zebrafish cranial neurulation
[作者:Nyholm, MK; Abdelilah-Seyfried, S; Grinblat, Y,期刊:Journal of cell science, 页码:2137-2148 , 文章类型: Article,,卷期:2009年122-12]
- During neurulation, vertebrate embryos form a neural tube (NT), the rudiment of the central nervous system. In mammals and birds, a key step in cranial NT morphogenesis is dorsolateral hinge-point (DLHP) bending, which r...
- CDK2 is required for proper homologous pairing, recombination and sex-body formation during male mouse meiosis
[作者:Viera, A; Rufas, JS; Martinez, I; Barbero, JL; Ortega, S; Suja, JA,期刊:Journal of cell science, 页码:2149-2159 , 文章类型: Article,,卷期:2009年122-12]
- Cyclin-dependent kinase 2 (CDK2) was assumed to be essential in the mammalian cell cycle both at the G1-S transition and throughout the S phase. Interestingly, ablation of Cdk2 in mice does not have substantial consequen...
- Inactivation of the C-elegans lipin homolog leads to ER disorganization and to defects in the breakdown and reassembly of the nuclear envelope
[作者:Golden, A; Liu, J; Cohen-Fix, O,期刊:Journal of cell science, 页码:1970-1978 , 文章类型: Article,,卷期:2009年122-12]
- The nuclear envelope (NE) is a dynamic structure, undergoing periods of growth, breakdown and reassembly during the cell cycle. In yeast, altering lipid synthesis by inactivating the yeast homolog of lipin, a phosphatidi...
- Role of kinesin-1 and cytoplasmic dynein in endoplasmic reticulum movement in VERO cells
[作者:Wozniak, MJ; Bola, B; Brownhill, K; Yang, YC; Levakova, V; Allan, VJ,期刊:Journal of cell science, 页码:1979-1989 , 文章类型: Article,,卷期:2009年122-12]
- Generating the extended endoplasmic reticulum ( ER) network depends on microtubules, which act as tracks for motor-driven ER tubule movement, generate the force to extend ER tubules by means of attachment to growing micr...
- Syntaxin 3 and SNAP-25 pairing, regulated by omega-3 docosahexaenoic acid, controls the delivery of rhodopsin for the biogenesis of cilia-derived sensory organelles, the rod outer segments
[作者:Mazelova, J; Ransom, N; Astuto-Gribble, L; Wilson, MC; Deretic, D,期刊:Journal of cell science, 页码:2003-2013 , 文章类型: Article,,卷期:2009年122-12]
- The biogenesis of cilia-derived sensory organelles, the photoreceptor rod outer segments (ROS), is mediated by rhodopsin transport carriers (RTCs). The small GTPase Rab8 regulates ciliary targeting of RTCs, but their spe...
- gamma-Tubulin-containing abnormal centrioles are induced by insufficient Plk4 in human HCT116 colorectal cancer cells
[作者:Kuriyama, R; Bettencourt-Dias, M; Hoffmann, I; Arnold, M; Sandvig, L,期刊:Journal of cell science, 页码:2014-2023 , 文章类型: Article,,卷期:2009年122-12]
- Cancer cells frequently induce aberrant centrosomes, which have been implicated in cancer initiation and progression. Human colorectal cancer cells, HCT116, contain aberrant centrioles composed of disorganized cylindrica...
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