- Mesenchymal stem cells in the colorectal tumor microenvironment: Recent progress and implications
[作者:Hogan, NM; Dwyer, RM; Joyce, MR; Kerin, MJ,期刊:International Journal of Cancer, 页码:1-7 , 文章类型: Article,,卷期:2012年131-1]
- Mesenchymal stem cells (MSCs) are nonhematopoietic multipotent adult stem cells. They have been shown to have a natural tropism for many tumors types, including colorectal, and are capable of escaping host immune surveil...
- The tumor microenvironment expression of p-STAT3 influences the efficacy of cyclophosphamide with WP1066 in murine melanoma models
[作者:Hatiboglu, MA; Kong, LY; Wei, J; Wang, YT; McEnery, KA; Fuller, GN; Qiao, W; Davies, MA; Priebe, W; Heimberger, AB,期刊:International Journal of Cancer, 页码:8-17 , 文章类型: Article,,卷期:2012年131-1]
- Melanoma is a common and deadly tumor that upon metastasis to the central nervous system (CNS) has median survival duration of less than 5 months. Activation of the signal transducer and activator of transcription 3 (STA...
- Epigenetic regulation by decitabine of melanoma differentiation in vitro and in vivo
[作者:Alcazar, O; Achberger, S; Aldrich, W; Hu, ZB; Negrotto, S; Saunthararajah, Y; Triozzi, P,期刊:International Journal of Cancer, 页码:18-29 , 文章类型: Article,,卷期:2012年131-1]
- Apoptosis genes, such as TP53 and p16/CDKN2A, that mediate responses to cytotoxic chemotherapy, are frequently nonfunctional in melanoma. Differentiation may be an alternative to apoptosis for inducing melanoma cell cycl...
- Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics
[作者:Tang, SN; Fu, JS; Nall, D; Rodova, M; Shankar, S; Srivastava, RK,期刊:International Journal of Cancer, 页码:30-40 , 文章类型: Article,,卷期:2012年131-1]
- Activation of the sonic hedgehog (SHh) pathway is required for the growth of numerous tissues and organs and recent evidence indicates that this pathway is often recruited to stimulate growth of cancer stem cells (CSCs) ...
- The lymphangiogenic factor SOX 18: A key indicator to stage gastric tumor progression
[作者:Eom, BW; Jo, MJ; Kook, MC; Ryu, KW; Choi, IJ; Nam, BH; Kim, YW; Lee, JH,期刊:International Journal of Cancer, 页码:41-48 , 文章类型: Article,,卷期:2012年131-1]
- SOX group F genes are important regulators of angiogenesis and lymphangiogenesis. The aim of the present study was to examine the relationships between Sox group F expression and clinicopathological factors in gastric ca...
- Horizontal transmission and retention of malignancy, as well as functional human genes, after spontaneous fusion of human glioblastoma and hamster host cells in vivo
[作者:Goldenberg, DM; Zagzag, D; Heselmeyer-Haddad, KM; Garcia, LYB; Ried, T; Loo, M; Chang, CH; Gold, DV,期刊:International Journal of Cancer, 页码:49-58 , 文章类型: Article,,卷期:2012年131-1]
- Cell fusion in vitro has been used to study cancer, gene mapping and regulation, and the production of antibodies via hybridomas. However, in-vivo heterosynkaryon formation by cellcell fusion has received less attention....
- Characterization of a new trabectedin-resistant myxoid liposarcoma cell line that shows collateral sensitivity to methylating agents
[作者:Uboldi, S; Bernasconi, S; Romano, M; Marchini, S; Nerini, IF; Damia, G; Ganzinelli, M; Marangon, E; Sala, F; Clivio, L; Chiorino, G; Di Giandomenico, S; Rocchi, M; Capozzi, O; Margison, GP; Watson, AJ; Caccuri, AM; Pastore, A; Fossati, A; Mantovani, R; Grosso, F; Tercero, JC; Erba, E; D'Incalci, M,期刊:International Journal of Cancer, 页码:59-69 , 文章类型: Article,,卷期:2012年131-1]
- Myxoid Liposarcomas (MLS), characterized by the expression of FUS-CHOP fusion gene are clinically very sensitive to the DNA binding antitumor agent, trabectedin. However, resistance eventually occurs, preventing disease ...
- High-density lipoprotein of patients with type 2 diabetes mellitus elevates the capability of promoting migration and invasion of breast cancer cells
[作者:Pan, B; Ren, H; Ma, YJ; Liu, DH; Yu, BQ; Ji, L; Pan, L; Li, J; Yang, LG; Lv, XF; Shen, XL; Chen, B; Zhang, YY; Willard, B; He, YB; Zheng, LM,期刊:International Journal of Cancer, 页码:70-82 , 文章类型: Article,,卷期:2012年131-1]
- Epidemiological studies suggested complicated associations between type 2 diabetes mellitus and breast cancer. There is a significant inverse association between high-density lipoprotein (HDL) and the risk and mortality ...
- BARD1: An independent predictor of survival in non-small cell lung cancer
[作者:Zhang, YQ; Bianco, A; Malkinson, AM; Leoni, VP; Frau, G; De Rosa, N; Andre, PA; Versace, R; Boulvain, M; Laurent, GJ; Atzori, L; Irminger-Finger, I,期刊:International Journal of Cancer, 页码:83-94 , 文章类型: Article,,卷期:2012年131-1]
- BRCA1 mRNA overexpression is correlated with poor survival in NSCLC. However, BRCA1 functions depend on the interaction with BARD1 for its stability, nuclear localization and ubiquitin ligase activity. Expression of alte...
- Meta-analysis of gene expression profiles associated with histological classification and survival in 829 ovarian cancer samples
[作者:Fekete, T; Raso, E; Pete, I; Tegze, B; Liko, I; Munkacsy, G; Sipos, N; Rigo, J; Gyorffy, B,期刊:International Journal of Cancer, 页码:95-105 , 文章类型: Article,,卷期:2012年131-1]
- Transcriptomic analysis of global gene expression in ovarian carcinoma can identify dysregulated genes capable to serve as molecular markers for histology subtypes and survival. The aim of our study was to validate previ...
- Efficacy of the human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine in women aged 15-25 years with and without serological evidence of previous exposure to HPV-16/18
[作者:Szarewski, A; Poppe, WAJ; Skinner, SR; Wheeler, CM; Paavonen, J; Naud, P; Salmeron, J; Chow, SN; Apter, D; Kitchener, H; Castellsague, X; Teixeira, JC; Hedrick, J; Jaisamrarn, U; Limson, G; Garland, S; Romanowski, B; Aoki, FY; Schwarz, TF; Bosch, FX; Harper, DM; Hardt, K; Zahaf, T; Descamps, D; Struyf, F; Lehtinen, M; Dubin, G,期刊:International Journal of Cancer, 页码:106-116 , 文章类型: Article,,卷期:2012年131-1]
- In the Phase III PATRICIA study (NCT00122681), the human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine (Cervarix (R), GlaxoSmithKline Biologicals) was highly efficacious against HPV-16/18 infections and precancerous...
- Differential glycosylation of MUC1 and CEACAM5 between normal mucosa and tumour tissue of colon cancer patients
[作者:Saeland, E; Belo, AI; Mongera, S; van Die, I; Meijer, GA; van Kooyk, Y,期刊:International Journal of Cancer, 页码:117-128 , 文章类型: Article,,卷期:2012年131-1]
- Altered glycosylation in epithelial cancers may play an important role in tumour progression, as it may affect tumour cell migration and antigen presentation by antigen presenting cells. We specifically characterise the ...
- Promiscuous survivin peptide induces robust CD4+T-cell responses in the majority of vaccinated cancer patients
[作者:Widenmeyer, M; Griesemann, H; Stevanovic, S; Feyerabend, S; Klein, R; Attig, S; Hennenlotter, J; Wernet, D; Kuprash, DV; Sazykin, AY; Pascolo, S; Stenzl, A; Gouttefangeas, C; Rammensee, HG,期刊:International Journal of Cancer, 页码:140-149 , 文章类型: Article,,卷期:2012年131-1]
- CD4+ T cells have been shown to be crucial for the induction and maintenance of cytotoxic T cell responses and to be also capable of mediating direct tumor rejection. Therefore, the anticancer therapeutic efficacy of pep...
- HLA-G expression is associated with metastasis and poor survival in the Balb/c nu/nu murine tumor model with ovarian cancer
[作者:Lin, AF; Zhang, X; Xu, HH; Xu, DP; Ruan, YY; Yan, WH,期刊:International Journal of Cancer, 页码:150-157 , 文章类型: Article,,卷期:2012年131-1]
- Aberrant HLA-G expression is associated with tumor invasiveness and poor clinical prognosis; however, there is a lack of preclinical animal model to address whether HLA-G plays a causal role in the unfavorable prognosis ...
- Detection of mitochondrial deoxyribonucleic acid alterations in urine from urothelial cell carcinoma patients
[作者:Dasgupta, S; Shao, CB; Keane, TE; Duberow, DP; Mathies, RA; Fisher, PB; Kiemeney, LA; Sidransky, D,期刊:International Journal of Cancer, 页码:158-164 , 文章类型: Article,,卷期:2012年131-1]
- Our study aims at understanding the timing and nature of mitochondrial deoxyribonucleic acid (mtDNA) alterations in urothelial cell carcinoma (UCC) and their detection in urine sediments. The entire 16.5 kb mitochondrial...
|