- Experimental anti-angiogenesis causes upregulation of genes associated with poor survival in glioblastoma
[作者:Saidi, A; Javerzat, S; Bellahcene, A; De Vos, J; Bello, L; Castronovo, V; Deprez, M; Loiseau, H; Bikfalvi, A; Hagedorn, M,期刊:International Journal of Cancer, 页码:2187-2198 , 文章类型: Article,,卷期:2008年122-10]
- Vascular endothelial growth factor (VEGF) inhibitors are the most promising anti-angiogenic agents used increasingly in the clinic. However, to be efficient, anti-VEGF agents need to be associated with classic chemothera...
- Calpain-mediated pathway dominates cisplatin-induced apoptosis in human lung adenocarcinoma cells as determined by real-time single cell analysis
[作者:Liu, L; Xing, D; Chen, WR; Chen, TS; Pei, YH; Gao, XJ,期刊:International Journal of Cancer, 页码:2210-2222 , 文章类型: Article,,卷期:2008年122-10]
- Cisplatin is an efficient anticancer agent. Cisplatin-based chemotherapy is believed to involve different signal transduction pathways, among which calpain activation has been proposed as an important factor in the induc...
- HMGA2 is the partner of MDM2 in well-differentiated and dedifferentiated liposarcomas whereas CDK4 belongs to a distinct inconsistent amplicon
[作者:Italiano, A; Bianchini, L; Keslair, F; Bonnafous, S; Cardot-Leccia, N; Coindre, JM; Dumollard, JM; Hofman, P; Leroux, A; Mainguene, C; Peyrottes, I; Ranchere-Vince, D; Terrier, P; Tran, A; Gual, P; Pedeutour, F,期刊:International Journal of Cancer, 页码:2233-2241 , 文章类型: Article,,卷期:2008年122-10]
- Data concerning the fine structure of the 12q13-15 amplicon which contains MDM2 and CDK4 in well-differentiated and dedifferentiated liposarcomas (WDLPS/DDLPS) are scarce. We investigated a series of 38 WDLPS/DDLPS using...
- Quantitation of HER2 and telomerase biomarkers in solid tumors with IgY antibodies and nanocrystal detection
[作者:Xiao, Y; Gao, XG; Gannot, G; Emmert-Buck, MR; Srivastava, S; Wagner, PD; Amos, MD; Barker, PE,期刊:International Journal of Cancer, 页码:2178-2186 , 文章类型: Article,,卷期:2008年122-10]
- In an effort to improve affinity biomarker validation in fixed patient tissue specimens, we have developed a novel quantum dot-based bioimaging system that utilizes chicken IgY antibody for high sensitivity and specifici...
- Serum lipid levels and the risk of biliary tract cancers and biliary stones: A population-based study in China
[作者:Andreotti, G; Chen, JB; Gao, YT; Rashid, A; Chang, SC; Shen, MC; Wang, BS; Han, TQ; Zhang, BH; Danforth, KN; Althuis, MD; Hsing, AW,期刊:International Journal of Cancer, 页码:2322-2329 , 文章类型: Article,,卷期:2008年122-10]
- Biliary tract cancers, encompassing the gallbladder, extrahepatic bile diicts and ampulla of Vater, are rare but highly fatal malignancies. Gallstones, the predominant risk factor for biliary cancers, are linked with hyp...
- Designing antibodies for the inhibition of gastrin activity in tumoral cell lines
[作者:Barderas, R; Shochat, S; Timmerman, P; Hollestelle, MJ; Martinez-Torrecuadrada, JL; Hoppener, JWM; Altschuh, D; Meloen, R; Casal, JI,期刊:International Journal of Cancer, 页码:2351-2359 , 文章类型: Article,,卷期:2008年122-10]
- Gastrin and its derivatives are becoming important targets for immunotherapy of pancreatic, gastric and colorectal tumors. This study was conducted to design antibodies able to block gastrin binding to the gastrin/cholec...
- Treatment with ozone/oxygen-pneumoperitoneum results in complete remission of rabbit squamous cell carcinomas
[作者:Schulz, S; Haussler, U; Mandic, R; Heverhagen, JT; Neubauer, A; Dunne, AA; Werner, JA; Weihe, E; Bette, M,期刊:International Journal of Cancer, 页码:2360-2367 , 文章类型: Article,,卷期:2008年122-10]
- Head and neck squamous cell carcinomas (HNSCC) represent a group of metastasizing tumors with a high mortality rate in man and animals. Since the biomolecule ozone was found to inhibit growth of various carcinoma cells i...
- Targeting prostate cancer with HTI-286, a synthetic analog of the marine sponge product hemiasterlin
[作者:Hadaschik, BA; Ettinger, S; Sowery, RD; Zoubeidi, A; Andersen, RJ; Roberge, M; Gleave, ME,期刊:International Journal of Cancer, 页码:2368-2376 , 文章类型: Article,,卷期:2008年122-10]
- Therapeutic resistance is the underlying cause for most cancer deaths and a major problem associated with treatment of metastatic prostate cancer. HTI-286, a fully synthetic analog of the natural tripeptide hemiasterlin,...
- Cutaneous human papillomavirus infection, the EVER2 gene and incidence of squamous cell carcinoma: A case-control study
[作者:Patel, AS; Karagas, MR; Pawlita, M; Waterboer, T; Nelson, HH,期刊:International Journal of Cancer, 页码:2377-2379 , 文章类型: Article,,卷期:2008年122-10]
- The first evidence of an association between HPV and non-melanoma skin cancer comes from patients with epidermodysplasia verruciformis (EV). EV is a rare heritable disease characterized by cutaneous warts that display no...
- Antibodies against the cancer-testis antigen CTSP-1 are frequently found in prostate cancer patients and are an independent prognostic factor for biochemical-recurrence
[作者:Parmigiani, RB; Bettoni, F; Grosso, DM; Lopes, A; Cunha, IW; Soares, FA; Carvalho, AL; Fonseca, F; Camargo, AA,期刊:International Journal of Cancer, 页码:2385-2390 , 文章类型: Article,,卷期:2008年122-10]
- Cancer-testis (CT) antigens are immunogenic proteins expressed in normal gametogenic tissues and in different types of tumors. CTSP-1 is a CT antigen frequently expressed in prostate tumors, and capable of eliciting Immo...
- High expression of Ran GTPase is associated with local invasion and metastasis of human clear cell renal cell carcinoma
[作者:Abe, H; Kamai, T; Shirataki, H; Oyama, T; Arai, K; Yoshida, KI,期刊:International Journal of Cancer, 页码:2391-2397 , 文章类型: Article,,卷期:2008年122-10]
- The Ran small GTPase (Ran) is involved in the regulation of nuclear transport, microtubule nucleation and dynamics, and spindle assembly. To address the question of whether Ran protein is associated with the progression ...
- Tobacco smoking and the risk of upper aero-digestive tract cancers: A reanalysis of case-control studies using spline models
[作者:Polesel, J; Talamini, R; La Vecchia, C; Levi, F; Barzan, L; Serraino, D; Franceschi, S; Dal Maso, L,期刊:International Journal of Cancer, 页码:2398-2402 , 文章类型: Article,,卷期:2008年122-10]
- Although tobacco smoking has long been recognized as a major risk factor for cancer of the upper aero-digestive tract (UADT, i.e., oral cavity, pharynx, larynx, and oesophagus), very few studies have provided estimates o...
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