- Curcumin induces cell-arrest and apoptosis in association with the inhibition of constitutively active NF-kappa B and STAT3 pathways in Hodgkin's lymphoma cells
[作者:Mackenzie, GG; Queisser, N; Wolfson, ML; Fraga, CG; Adamo, AM; Oteiza, PI,期刊:International Journal of Cancer, 页码:56-65 , 文章类型: Article,,卷期:2008年123-1]
- Although treatment of Hodgkin's lymphoma (HL) with a multidrug approach has been very successful, its toxicity becomes evident after several years as secondary malignancies and cardiovascular disease. Therefore, the curr...
- Estrogen-mediated downregulation of CD24 in breast cancer cells
[作者:Kaipparettu, BA; Malik, S; Konduri, SD; Liu, W; Rokavec, M; van der Kuip, H; Hoppe, R; Hammerich-Hille, S; Fritz, P; Schroth, W; Abele, I; Das, GM; Oesterreich, S; Brauch, H,期刊:International Journal of Cancer, 页码:66-72 , 文章类型: Article,,卷期:2008年123-1]
- We have previously reported on the relevance of the prevalence of CD44(+)/CD24(-/low),, cells in primary breast tumors. To study regulation of CD24, we queried a number of publicly available expression array studies in b...
- SPARC modulates the proliferation of stromal but not melanoma cells unless endogenous SPARC expression is downregulated (vol 122, pg 1465, 2008)
[作者:Haber, CL; Gottifredi, V; Llera, AS; Salvatierra, E; Prada, F; Alonso, L; Helene, SE; Podhacjer, OL,期刊:International Journal of Cancer, 页码:245-245 , 文章类型: Correction,,卷期:2008年123-1]
-
- Metastatic cancer cells with macrophage properties: Evidence from a new murine tumor model
[作者:Huysentruyt, LC; Mukherjee, P; Banerjee, D; Shelton, LM; Seyfried, TN,期刊:International Journal of Cancer, 页码:73-84 , 文章类型: Article,,卷期:2008年123-1]
- Metastasis is the process by which cancer cells disseminate from the primary neoplasm and invade surrounding tissue and distant organs, and is the primary cause of morbidity and mortality for cancer patients. Most conven...
- The aberrant methylation of TSF1 suppresses TGF-beta 1 activation in colorectal cancer
[作者:Rojas, A; Meherem, S; Kim, YH; Washington, MK; Willis, JE; Markowitz, SD; Grady, WM,期刊:International Journal of Cancer, 页码:14-21 , 文章类型: Article,,卷期:2008年123-1]
- Colorectal cancer arises from the progressive accumulation of mutations and epigenetic alterations in colon epithelial cells. Such alterations often deregulate signaling pathways that affect the formation of colon cancer...
- Expression and splicing of the unfolded protein response gene XBP-1 are sieniticantly associated with clinical outcome of endocrine-treated breast cancer
[作者:Davies, MPA; Barraclough, DL; Stewart, C; Joyce, KA; Eccles, RM; Barraclough, R; Rudland, PS; Sibson, DR,期刊:International Journal of Cancer, 页码:85-88 , 文章类型: Article,,卷期:2008年123-1]
- X-box binding protein 1 (XBP-1) is stimulated by endoplasmic reticulum stress as part of the unfolded protein response (UPR), which can promote apoptosis or cell survival. Non-conventional splicing, stimulated during the...
- FGF-8 is involved in bone metastasis of prostate cancer
[作者:Valta, MP; Tuomela, J; Bjartell, A; Valve, E; Vaananen, HK; Harkonen, P,期刊:International Journal of Cancer, 页码:22-31 , 文章类型: Article,,卷期:2008年123-1]
- Prostate cancer is the most common malignancy of men in Western countries. Patients with advanced prostate cancer suffer from incurable bone metastases. Recent data indicate that interactions between prostate cancer cell...
- Expression of CD175 (Tn), CD175s (sialosyl-Tn) and CD176 (Thomsen-Friedenreich antigen) on malignant human hematopoietic cells
[作者:Cao, Y; Merling, A; Karsten, U; Goletz, S; Punzel, M; Kraft, R; Butschak, G; Schwartz-Albiez, R,期刊:International Journal of Cancer, 页码:89-99 , 文章类型: Article,,卷期:2008年123-1]
- The expression of the histo-blood group carbohydrate structures T-nouvelle (Tn, CD175), sialylated To (CD175s) and the Thomsen-Friedenreich disaccharide (TF, CD176) on human leukemia cell lines was analyzed by their reac...
- Gene expression changes during HPV-mediated carcinogenesis: A comparison between an in vitro cell model and cervical cancer
[作者:Wan, F; Miao, XJ; Quraishi, I; Kennedy, V; Creek, KE; Pirisi, L,期刊:International Journal of Cancer, 页码:32-40 , 文章类型: Article,,卷期:2008年123-1]
- We used oligonucleotide microarrays to investigate gene expression changes associated with multi-step human papillomavirus type 16 (HPV16)-mediated carcinogenesis in vitro. Gene expression profiles in 4 early passage HPV...
- Nox1 is over-expressed in human colon cancers and correlates with activating mutations in K-Ras
[作者:Laurent, E; Mccoy, JW; Macina, RA; Liu, WH; Cheng, GJ; Robine, S; Papkoff, J; Lambeth, JD,期刊:International Journal of Cancer, 页码:100-107 , 文章类型: Article,,卷期:2008年123-1]
- The NADPH-oxidase 1 (Nox1) is a homolog of gp91phox, the catalytic subunit of the phagocyte superoxide-generating NADPH-oxidase. Nox1 is expressed in normal colon epithelial cells and in colon tumor cell lines, and overe...
- Oxidative DNA damage in gastric cancer: cagA status and OGG1 gene polymorphism
[作者:Farinati, F; Cardin, R; Bortolami, M; Nitti, D; Bass, D; de Bernard, M; Cassaro, M; Sergio, A; Rugge, M,期刊:International Journal of Cancer, 页码:51-55 , 文章类型: Article,,卷期:2008年123-1]
- Oxidative DNA damage is thought to play an important part in the pathogenesis of H. pylori-induced mucosal damage. 8-OHdG is a sensitive marker of DNA oxidation and is repaired by a polymorphic glycosylase (OGG1) more ef...
- TNF-alpha-inducing protein, a carcinogenic factor secreted from H. pylori, enters gastric cancer cells
[作者:Sujanuma, M; Yamaguchi, K; Ono, Y; Matsmmoto, H; Hayashi, T; Ogawa, T; Imai, K; Kuzuhara, T; Nishizon, A; Fujiki, H,期刊:International Journal of Cancer, 页码:117-122 , 文章类型: Article,,卷期:2008年123-1]
- TNF-alpha inducing protein (Tip alpha) is secreted from Helicobacter pylori (H. pylori): it is a potent inducer of TNF-alpha and chentokine genes, mediated through NF-kappa B activation, and it also induces tumor-promoti...
- Polymorphisms in MGMT and DNA repair genes and the risk of esophageal adenocarcinoma
[作者:Doecke, J; Zhao, ZZ; Pandeya, N; Sadeghi, S; Stark, M; Green, AC; Hayward, NK; Webb, PM; Whiteman, DC,期刊:International Journal of Cancer, 页码:174-180 , 文章类型: Article,,卷期:2008年123-1]
- Rates of adenocarcinoma of the esophagus (EAC) and esophagogastric junction (EGJAC) have increased rapidly in recent decades. The primary risk factors, gastro-esophageal acid reflux and smoking, are potentially genotoxic...
|