- Elucidating Nature's Solutions to Heart, Lung, and Blood Diseases and Sleep Disorders
[作者：Carey, HV; Martin, SL; Horwitz, BA; Yan, L; Bailey, SM; Podrabsky, J; Storz, JF; Ortiz, RM; Wong, RP; Lathrop, DA,期刊：Circulation Research, 页码：915-921 , 文章类型： Article，,卷期：2012年110-7]
- Evolution has provided a number of animal species with extraordinary phenotypes. Several of these phenotypes allow species to survive and thrive in environmental conditions that mimic disease states in humans. The study ...
- Islet1 Derivatives in the Heart Are of Both Neural Crest and Second Heart Field Origin
[作者：Engleka, KA; Manderfield, LJ; Brust, RD; Li, L; Cohen, A; Dymecki, SM; Epstein, JA,期刊：Circulation Research, 页码：922-U47 , 文章类型： Article，,卷期：2012年110-7]
- Rationale: Islet1 (Isl1) has been proposed as a marker of cardiac progenitor cells derived from the second heart field and is utilized to identify and purify cardiac progenitors from murine and human specimens for ex viv...
- Nanobodies Targeting Mouse/Human VCAM1 for the Nuclear Imaging of Atherosclerotic Lesions
[作者：Broisat, A; Hernot, S; Toczek, J; De Vos, J; Riou, LM; Martin, S; Ahmadi, M; Thielens, N; Wernery, U; Caveliers, V; Muyldermans, S; Lahoutte, T; Fagret, D; Ghezzi, C; Devoogdt, N,期刊：Circulation Research, 页码：927-937 , 文章类型： Article，,卷期：2012年110-7]
- Rationale: A noninvasive tool allowing the detection of vulnerable atherosclerotic plaques is highly needed. By combining nanomolar affinities and fast blood clearance, nanobodies represent potential radiotracers for car...
- Novel Genetic Approach for In Vivo Vascular Imaging in Mice
[作者：Bartelle, BB; Berrios-Otero, CA; Rodriguez, JJ; Friedland, AE; Aristizabal, O; Turnbull, DH,期刊：Circulation Research, 页码：938-U81 , 文章类型： Article，,卷期：2012年110-7]
- Rationale: The formation and maintenance of a functional vasculature is essential for normal embryonic development, and genetic changes that affect the vasculature underlie pathogenesis in many human diseases. In vivo im...
- A Cell-Based Phenotypic Assay to Identify Cardioprotective Agents
[作者：Guo, S; Olm-Shipman, A; Walters, A; Urciuoli, WR; Devito, S; Nadtochiy, SM; Wojtovich, AP; Brookes, PS,期刊：Circulation Research, 页码：948-U133 , 文章类型： Article，,卷期：2012年110-7]
- Rationale: Tissue ischemia/reperfusion (IR) injury underlies several leading causes of death such as heart-attack and stroke. The lack of clinical therapies for IR injury may be partly due to the difficulty of adapting I...
- A Human 3 ' miR-499 Mutation Alters Cardiac mRNA Targeting and Function
[作者：Dorn, GW; Matkovich, SJ; Eschenbacher, WH; Zhang, Y,期刊：Circulation Research, 页码：958-U161 , 文章类型： Article，,卷期：2012年110-7]
- Rationale: MyomiRs miR-499, miR-208a and miR-208b direct cardiac myosin gene expression. Sequence complementarity between miRs and their mRNA targets determines miR effects, but the functional consequences of human myomi...
- Actin Cytoskeleton Rest Stops Regulate Anterograde Traffic of Connexin 43 Vesicles to the Plasma Membrane
[作者：Smyth, JW; Vogan, JM; Buch, PJ; Zhang, SS; Fong, TS; Hong, TT; Shaw, RM,期刊：Circulation Research, 页码：978-U209 , 文章类型： Article，,卷期：2012年110-7]
- Rationale: The intracellular trafficking of connexin 43 (Cx43) hemichannels presents opportunities to regulate cardiomyocyte gap junction coupling. Although it is known that Cx43 hemichannels are transported along microt...
- MicroRNAs and Stem Cells Control of Pluripotency, Reprogramming, and Lineage Commitment
[作者：Heinrich, EM; Dimmeler, S,期刊：Circulation Research, 页码：1014-1022 , 文章类型： Review，,卷期：2012年110-7]
- Stem cells hold great promise for regenerative medicine and the treatment of cardiovascular diseases. The mechanisms regulating self-renewal, pluripotency, and differentiation are not fully understood. MicroRNAs (miRs) a...
|