- High-yield cell-free protein synthesis for site-specific incorporation of unnatural amino acids at two sites
[作者:Ozawa, K; Loscha, KV; Kuppan, KV; Loh, CT; Dixon, NE; Otting, G,期刊:Biochemical and Biophysical Research Communications, 页码:652-656 , 文章类型: Article,,卷期:2012年418-4]
- Using aminoacyl-tRNA synthetase/suppressor tRNA pairs derived from Methanocaldococcus jannaschii, an Escherichia coli cell-free protein production system affords proteins with site-specifically incorporated unnatural ami...
- Upregulation of thromboxane synthase mediates visfatin-induced interleukin-8 expression and angiogenic activity in endothelial cells
[作者:Kim, SR; Jung, YH; Park, HJ; Kim, MK; Jeong, JW; Jang, HO; Yun, I; Bae, SK; Bae, MK,期刊:Biochemical and Biophysical Research Communications, 页码:662-668 , 文章类型: Article,,卷期:2012年418-4]
- Thromboxane synthase (TXAS) is an enzyme that catalyzes the synthesis of thromboxane A(2) (TXA(2)). Overexpression of TXAS is associated with a variety of vascular diseases. Recently, we reported that visfatin, a novel a...
- IL-3 promotes osteoblast differentiation and bone formation in human mesenchymal stem cells
[作者:Barhanpurkar, AP; Gupta, N; Srivastava, RK; Tomar, GB; Naik, SP; Joshi, SR; Pote, ST; Mishra, GC; Wani, MR,期刊:Biochemical and Biophysical Research Communications, 页码:669-675 , 文章类型: Article,,卷期:2012年418-4]
- IL-3 is an important cytokine that regulates hematopoiesis. We have previously demonstrated that IL-3 is a potent inhibitor of osteoclastogenesis and bone resorption. In the present study, we have investigated the role o...
- A novel adipocytokine, nesfatin-1 modulates peripheral arterial contractility and blood pressure in rats
[作者:Yamawaki, H; Takahashi, M; Mukohda, M; Morita, T; Okada, M; Hara, Y,期刊:Biochemical and Biophysical Research Communications, 页码:676-681 , 文章类型: Article,,卷期:2012年418-4]
- Nesfatin-1 is a novel adipocytokine which exerts not only anorexigenic but also hypertensive roles through acting on hypothalamus melanocortin-3/4 receptors. Although it is logical to hypothesize that nesfatin-1 could al...
- A p53-inducible microRNA-34a downregulates Ras signaling by targeting IMPDH
[作者:Kim, HR; Roe, JS; Lee, JE; Hwang, IY; Cho, EJ; Youn, HD,期刊:Biochemical and Biophysical Research Communications, 页码:682-688 , 文章类型: Article,,卷期:2012年418-4]
- p53 is a well-known transcription factor that controls cell cycle arrest and cell death in response to a wide range of stresses. Moreover, p53 regulates glucose metabolism and its mutation results in the metabolic switch...
- A fraction of neurofibromin interacts with PML bodies in the nucleus of the CCF astrocytoma cell line
[作者:Godin, F; Villette, S; Vallee, B; Doudeau, M; Morisset-Lopez, S; Ardourel, M; Hevor, T; Pichon, C; Benedetti, H,期刊:Biochemical and Biophysical Research Communications, 页码:689-694 , 文章类型: Article,,卷期:2012年418-4]
- Neurofibromatosis type 1 is a common genetic disease that causes nervous system tumors, and cognitive deficits. It is due to mutations within the NF1 gene, which encodes the Nf1 protein. Nf1 has been shown to be involved...
- Notch2 regulates the development of marginal zone B cells through Fos
[作者:Iwahashi, S; Maekawa, Y; Nishida, J; Ishifune, C; Kitamura, A; Arimochi, H; Kataoka, K; Chiba, S; Shimada, M; Yasutomo, K,期刊:Biochemical and Biophysical Research Communications, 页码:701-707 , 文章类型: Article,,卷期:2012年418-4]
- B cells are classified into several subsets depending on their functions, marker expression pattern and localization. Marginal zone B (MZB) cells are a distinct lineage from follicular B cells, and regulate host defenses...
- CD38 is a key enzyme for the survival of mouse microglial BV2 cells
[作者:Ma, YX; Jiang, JW; Wang, L; Nie, H; Xia, WL; Liu, JR; Ying, WH,期刊:Biochemical and Biophysical Research Communications, 页码:714-719 , 文章类型: Article,,卷期:2012年418-4]
- CD38 is a multifunctional enzyme that can not only generate cyclic adenosine diphosphate-ribose (cADPR) - a key Ca2+ -mobilizing second messenger - by consuming NAD(+), but also hydrolyze extracellular NAD(+). There have...
- p-Synephrine stimulates glucose consumption via AMPK in L6 skeletal muscle cells
[作者:Hong, NY; Cui, ZG; Kang, HK; Lee, DH; Lee, YK; Park, DB,期刊:Biochemical and Biophysical Research Communications, 页码:720-724 , 文章类型: Article,,卷期:2012年418-4]
- Interest in p-synephrine, the primary protoalkaloid in the extract of bitter orange and other citrus species, has increased due to its various pharmacological effects and related adverse effects. The lipolytic activity o...
- Effects of strontium on proliferation and differentiation of rat bone marrow mesenchymal stem cells
[作者:Li, YF; Li, JH; Zhu, SS; Luo, E; Feng, G; Chen, QM; Hu, J,期刊:Biochemical and Biophysical Research Communications, 页码:725-730 , 文章类型: Article,,卷期:2012年418-4]
- Strontium ranelate (SrR) was an effective anti-osteoporotic drug to increase bone formation and decrease bone resorption. However, reports about the effect of SR on osteoblastic and adipocytic differentiation from bone m...
- Both El Tor and classical cholera toxin bind blood group determinants
[作者:Heggelund, JE; Haugen, E; Lygren, B; Mackenzie, A; Holmner, A; Vasile, F; Reina, JJ; Bernardi, A; Krengel, U,期刊:Biochemical and Biophysical Research Communications, 页码:731-735 , 文章类型: Article,,卷期:2012年418-4]
- Cholera is a disease which shows a clear blood group profile, with blood group 0 individuals experiencing the most severe symptoms. For a long time, the cholera toxin has been suspected to be the main culprit of this blo...
- Chromatin plasticity as a differentiation index during muscle differentiation of C2C12 myoblasts
[作者:Watanabe, TM; Higuchi, S; Kawauchi, K; Tsukasaki, Y; Ichimura, A; Fujita, H,期刊:Biochemical and Biophysical Research Communications, 页码:742-747 , 文章类型: Article,,卷期:2012年418-4]
- Skeletal muscle undergoes complicated differentiation steps that include cell-cycle arrest, cell fusion, and maturation, which are controlled through sequential expression of transcription factors. During muscle differen...
- Chemically dimerized intravenous immunoglobulin has potent ameliorating activity in a mouse immune thrombocytopenic purpura model
[作者:Machino, Y; Suzuki, E; Higurashi, S; Ohta, H; Suzuki, M; Kohroki, J; Masuho, Y,期刊:Biochemical and Biophysical Research Communications, 页码:748-753 , 文章类型: Article,,卷期:2012年418-4]
- High-dose intravenous immunoglobulin (IVIG) preparations are currently used for the treatment of autoimmune diseases such as immune thrombocytopenic purpura (ITP). Although the mechanisms of IVIG efficacy remain enigmati...
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