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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共14条记录   The plant endoplasmic reticulum: a cell-wide web [作者：Sparkes, IA; Frigerio, L; Tolley, N; Hawes, C,期刊：Biochemical Journal, 页码：145-155 , 文章类型： Review，,卷期：2009年423-Part 2] The ER (endoplasmic reticulum) in higher plants forms a pleomorphic web of membrane tubules and small cisternae that pervade the cytoplasm, but in particular form a polygonal network at the cortex of the cell which may b... Mechanisms of double-strand break repair in somatic mammalian cells [作者：Hartlerode, AJ; Scully, R,期刊：Biochemical Journal, 页码：157-168 , 文章类型： Review，,卷期：2009年423-Part 2] DNA chromosomal DSBs (double-strand breaks) are potentially hazardous DNA lesions, and their accurate repair is essential for the successful maintenance and propagation of genetic information. Two major pathways have evo... Nitric oxide stimulates myoglobin gene and protein expression in vascular smooth muscle [作者：Rayner, BS; Hua, S; Sabaretnam, T; Witting, PK,期刊：Biochemical Journal, 页码：169-177 , 文章类型： Article，,卷期：2009年423-Part 2] Mb (myoglobin) is a haemoprotein present in cardiac, skeletal and smooth muscle and is primarily responsible for the storage and 'facilitated transfer' of molecular oxygen from the cell membrane to mitochondria. Also, Mb... Binding of the CHD4 PHD2 finger to histone H3 is modulated by covalent modifications [作者：Musselman, CA; Mansfield, RE; Garske, AL; Davrazou, F; Kwan, AH; Oliver, SS; O'Leary, H; Denu, JM; Mackay, JP; Kutateladze, TG,期刊：Biochemical Journal, 页码：179-187 , 文章类型： Article，,卷期：2009年423-Part 2] CHD4 (chromodomain helicase DNA-binding protein 4) ATPase is a major Subunit of the repressive NuRD (nucleosome remodelling and deacetylase) complex, which is involved in transcriptional regulation and development. CHD4 ... Glucocorticoids can activate the alpha-EnaC gene promoter independently of SGK1 [作者：McTavish, N; Getty, J; Burchell, A; Wilson, SM,期刊：Biochemical Journal, 页码：189-197 , 文章类型： Article，,卷期：2009年423-Part 2] The role of SGK1 (serum- and glucocorticoid-induced protein kinase 1) in the glucocorticoid induction of alpha-ENaC (epithelial Na+ channel alpha subunit) gene transcription was explored by rnonitoring the transcriptiona... Structure of a trimeric bacterial microcompartment shell protein, EtuB, associated with ethanol utilization in Clostridium kluyveri [作者：Heldt, D; Frank, S; Seyedarabi, A; Ladikis, D; Parsons, JB; Warren, MJ; Pickersgill, RW,期刊：Biochemical Journal, 页码：199-207 , 文章类型： Article，,卷期：2009年423-Part 2] It has been suggested that ethanol metabolism in the strict anaerobe Clostridium kluyveri occurs within a metabolosome, a subcellular proteinaceous bacterial microcompartment. Two bacterial microcompartment shell protein... Mapping of the ligand-binding site on the b ' domain of human PDI: interaction with peptide ligands and the x-linker region [作者：Byrne, LJ; Sidhu, A; Wallis, AK; Ruddock, LW; Freedman, RB; Howard, MJ; Williamson, RA,期刊：Biochemical Journal, 页码：209-217 , 文章类型： Article，,卷期：2009年423-Part 2] PDI (protein disulfide-isomerase) catalyses the formation of native disulfide bonds of secretory proteins in the endoplasmic reticulum. PDI consists of four thioredoxin-like domains, of which two contain redox-active cat... Nitration of tyrosine residues 368 and 345 in the beta-subunit elicits F0F1-ATPase activity loss [作者：Fujisawa, Y; Kato, K; Giulivi, C,期刊：Biochemical Journal, 页码：219-231 , 文章类型： Article，,卷期：2009年423-Part 2] Tyrosine nitration is a covalent post-translational protein modification associated with various diseases related to oxidative/nitrative stress. A role for nitration of tyrosine in protein inactivation has been proposed;... Biochemical consequences of sedlin mutations that cause spondyloepiphyseal dysplasia tarda [作者：Choi, MY; Chan, CCY; Chan, D; Luk, KDK; Cheah, KSE; Tanner, JA,期刊：Biochemical Journal, 页码：233-242 , 文章类型： Article，,卷期：2009年423-Part 2] SEDT (spondyloepiphyseal dysplasia tarda) is a late-onset X-linked recessive skeletal dysplasia caused by mutations in the gene SEDL coding for sedlin. In the present paper, we investigated four missense mutations observ... Pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) deficiency attenuates the long-term negative effects of a high-saturated fat diet [作者：Hwang, B; Jeoung, NH; Harris, RA,期刊：Biochemical Journal, 页码：243-252 , 文章类型： Article，,卷期：2009年423-Part 2] The hypothesis that PDHK4 (pyruvate dehydrogenase kinase isoenzyme 4) has potential as a target for the treatment of type 2 diabetes was tested by feeding wild-type and PDHK4 knockout mice a high saturated fat diet that ... Oxidative modifications of glyceraldehyde-3-phosphate dehydrogenase play a key role in its multiple cellular functions [作者：Hwang, NR; Yim, SH; Kim, YM; Jeong, J; Song, EJ; Lee, Y; Lee, JH; Choi, S; Lee, KJ,期刊：Biochemical Journal, 页码：253-264 , 文章类型： Article，,卷期：2009年423-Part 2] Knowledge of the cellular targets of ROS (reactive oxygen species) and their regulation is an essential prerequisite for understanding ROS-mediated signalling. GAPDH (glyceraldehyde-3-phosphate dehydrogenase) is known as... The C-terminal domain is sufficient for endonuclease activity of Neisseria gonorrhoeae MutL [作者：Duppatla, V; Bodda, C; Urbanke, C; Friedhoff, P; Rao, DN,期刊：Biochemical Journal, 页码：265-277 , 文章类型： Article，,卷期：2009年423-Part 2] The mutL gene of Neisseria gonorrhoeae has been cloned and the gene product purified. We have found that the homodimeric N. gonorrhoeae MutL (NgoL) protein displays an endonuclease activity that incises covalently closed... The C-terminal domain of Mnk1a plays a dual role in tightly regulating its activity [作者：Goto, S; Yao, Z; Proud, CG,期刊：Biochemical Journal, 页码：279-290 , 文章类型： Article，,卷期：2009年423-Part 2] The human family of MAPK (mitogen-activated protein kinase) signal-integrating kinases (Mnks) comprises four related proteins derived from two genes by alternative splicing. The MNK1 gene gives rise to two proteins, Mnk1... RNase R mutants elucidate the catalysis of structured RNA: RNA-binding domains select the RNAs targeted for degradation [作者：Matos, RG; Barbas, A; Arraiano, CM,期刊：Biochemical Journal, 页码：291-301 , 文章类型： Article，,卷期：2009年423-Part 2] The RNase II superfamily is a ubiquitous family of exoribonucleases that are essential for RNA metabolism. RNase II and RNase R degrade RNA in the 3' -> 5' direction in a processive and sequence-independent manner. Howev...