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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共15条记录   RNAP subunits F/E (RPB4/7) are stably associated with archaeal RNA polymerase: using fluorescence anisotropy to monitor RNAP assembly in vitro [作者：Grohmann, D; Hirtreiter, A; Werner, F,期刊：Biochemical Journal, 页码：339-343 , 文章类型： Article，,卷期：2009年421-Part 3] Archaeal and eukaryotic RNAPs (DNA-dependent RNA polymerases) are complex multi-subunit enzymes. Two of the subunits, F and E, which together form the F/E complex, have been hypothesized to associate with RNAP in a rever... Interaction of anion exchanger 1 and glycophorin A in human erythroleukaemic K562 cells [作者：Pang, AJ; Reithmeier, RAF,期刊：Biochemical Journal, 页码：345-356 , 文章类型： Article，,卷期：2009年421-Part 3] AE1 [anion exchanger 1, also known as SLC4A1 (solute carrier family 4, anion exchanger, member 1) and band 3 (erythrocyte membrane protein hand 3)] is a major membrane glycoprotein expressed in human erythrocytes where i... Dual acylation is required for trafficking of growth-associated protein-43 (GAP-43) to endosomal recycling compartment via an Arf6-associated endocytic vesicular pathway [作者：Trenchi, A; Gomez, GA; Daniott, JL,期刊：Biochemical Journal, 页码：357-369 , 文章类型： Article，,卷期：2009年421-Part 3] GAP-43 (growth-associated protein-43) is it dually palmitoylated protein, at cysteine residues at positions 3 and 4, that mostly localizes in plasma membrane both in neural and non-neural cells. In the present study, we ... Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion [作者：Pound, LD; Sarkar, SA; Benninger, RKP; Wang, YD; Suwanichkul, A; Shadoan, MK; Printz, RL; Oeser, JK; Lee, CE; Piston, DW; McGuinness, OP; Hutton, JC; Powell, DR; O'Brien, RM,期刊：Biochemical Journal, 页码：371-376 , 文章类型： Article，,卷期：2009年421-Part 3] The Slc30a8 gene encodes the islet-specific zinc transporter ZnT-8, which provides zinc for insulin-hexamer formation. Polymorphic variants in amino acid residue 325 of human ZnT-8 are associated with altered susceptibil... Dynasore inhibits removal of wild-type and Delta F508 cystic fibrosis transmembrane conductance regulator (CFTR) from the plasma membrane [作者：Young, A; Gentzsch, M; Abban, CY; Jia, Y; Meneses, PI; Bridges, RJ; Bradbury, NA,期刊：Biochemical Journal, 页码：377-385 , 文章类型： Article，,卷期：2009年421-Part 3] Dynasore, a small molecule inhibitor of dynamin, Was used to probe the role of dynamin in the endocytosis of wild-type and mutant CFTR (cystic fibrosis transmembrane conductance regulator). Internalization of both wild-t... Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2 [作者：Cozza, G; Mazzorana, M; Papinutto, E; Bain, J; Elliott, M; Di Maira, G; Gianoncelli, A; Pagano, MA; Sarno, S; Ruzzene, M; Battistutta, R; Meggio, F; Moro, S; Zagotto, G; Pinna, LA,期刊：Biochemical Journal, 页码：387-395 , 文章类型： Article，,卷期：2009年421-Part 3] Emodin (1,3,8-trihydroxy-6-methyl-anthraquinone) is a moderately potent and poorly selective inhibitor of protein kinase CK2, one of the most pleiotropic serine/threonine protein kinases, implicated in neoplasia and in o... Variably modulated gating of the 26S proteasome by ATP and polyubiquitin [作者：Li, XH; DeMartino, GN,期刊：Biochemical Journal, 页码：397-404 , 文章类型： Article，,卷期：2009年421-Part 3] The 26S proteasome is it 2500 kDa protease complex that degrades polyubiquitylated proteins by a mechanism that requires ATP hydrolysis. It also degrades short non-ubiquitylated peptides and certain unstructured proteins... PKC epsilon has an alcohol-binding site in its second cysteine-rich regulatory domain [作者：Das, J; Pany, S; Rahman, GM; Slater, SJ,期刊：Biochemical Journal, 页码：405-413 , 文章类型： Article，,卷期：2009年421-Part 3] Alcohols regulate the expression and function of PKC (protein kinase C), and it has been proposed that ail alcohol-binding site is present in PKC alpha in its C1 domain, which consists of two cysteine-rich subdomains, C1... Antiparallel beta-sheet: a signature structure of the oligomeric amyloid beta-peptide [作者：Cerf, E; Sarroukh, R; Tamamizu-Kato, S; Breydo, L; Derclaye, S; Dufrene, YF; Narayanaswami, V; Goormaghtigh, E; Ruysschaert, JM; Raussens, V,期刊：Biochemical Journal, 页码：415-423 , 文章类型： Article，,卷期：2009年421-Part 3] AD (Alzheimer's disease) is linked to A beta (amyloid beta-peptide) misfolding. Studies demonstrate that the level Of Soluble A beta oligomeric forms correlates better with the progression of the disease than the level o... Bactericidal and membrane disruption activities of the eosinophil cationic protein are largely retained in an N-terminal fragment [作者：Torrent, M; de la Torre, BG; Nogues, VM; Andreu, D; Boix, E,期刊：Biochemical Journal, 页码：425-434 , 文章类型： Article，,卷期：2009年421-Part 3] ECP (eosinophil cationic protein) is an eosinophil secretion protein with antipathogen activities involved in the host immune defence system. The bactericidal capacity of ECP relies on its action oil both the plasma memb... Artificial beta-defensin based on a minimal defensin template [作者：Antcheva, N; Morgera, F; Creatti, L; Vaccari, L; Pag, U; Pacor, S; Shai, Y; Sahl, HG; Tossi, A,期刊：Biochemical Journal, 页码：435-447 , 文章类型： Article，,卷期：2009年421-Part 3] We have designed and chemically synthesized all artificial beta-defensin based on a minimal template derived from the comparative analysis of over 80 naturally occurring Sequences. This molecule has the disulfide-bridged... SUMOylation enhances DNA methyltransferase 1 activity [作者：Lee, B; Muller, MT,期刊：Biochemical Journal, 页码：449-461 , 文章类型： Article，,卷期：2009年421-Part 3] DNA methylation regulates gene expression through Complex network of protein-protein and protein-DNA interactions in chromatin. The maintenance methylase, DNMT1 (DNA methyltransferase 1), is a prominent enzyme in the pro... Overexpression of Drosophila mitoferrin in I(2)mbn cells results in dysregulation of Fer1HCH expression [作者：Metzendorf, C; Wu, WL; Lind, MI,期刊：Biochemical Journal, 页码：463-471 , 文章类型： Article，,卷期：2009年421-Part 3] Mrs3p and Mrs4p (Mrs3/4p) are yeast mitochondrial iron carrier proteins that play important roles in ISC (iron-sulphur cluster) and haem biosynthesis. At low iron conditions, rnitochondrial and cytoplasmic ISC protein ma... Glycyrrhizin, the main active compound in liquorice, attenuates pro-inflammatory responses by interfering with membrane-dependent receptor signalling [作者：Schrofelbauer, B; Raffetseder, J; Hauner, M; Wolkerstorfer, A; Ernst, W; Szolar, OHJ,期刊：Biochemical Journal, 页码：473-482 , 文章类型： Article，,卷期：2009年421-Part 3] The triterpene glycoside glycyrrhizin is the main active compound in liquorice. It is used as it herbal medicine owing to its anticancer, antiviral and anti-inflammatory properties. Its mode of action, however, remains w... Polyamine catabolism and disease [作者：Casero, RA; Pegg, AE,期刊：Biochemical Journal, 页码：323-338 , 文章类型： Review，,卷期：2009年421-Part 3] In addition to polyamine homoeostasis, it has become increasingly clear that polyamine catabolism call play a dominant role in drug response, apoptosis and the response 10 stressful, and contribute to the aetiology of se...