- Activation of mitochondrial mu-calpain increases AIF cleavage in cardiac mitochondria during ischemia-reperfusion
[作者:Chen, Q; Paillard, M; Gomez, L; Ross, T; Hu, Y; Xu, AJ; Lesnefsky, EJ,期刊:Biochemical and Biophysical Research Communications, 页码:533-538 , 文章类型: Article,,卷期:2011年415-4]
- Ubiquitous calpains (calpain I and II) are generally recognized as cytosolic proteins. Recently, mitochondrial localized calpain I (mu-calpain) has been identified. Activation of mito-mu-calpain cleaves apoptosis inducin...
- Adrenomedullin: A possible regulator of germinal vesicle breakdown
[作者:Hiradate, Y; Ohtake, J; Hoshino, Y; Tanemura, K; Sato, E,期刊:Biochemical and Biophysical Research Communications, 页码:691-695 , 文章类型: Article,,卷期:2011年415-4]
- Adrenomedullin (ADM) is a multifunctional hormone that regulates processes as diverse as blood pressure and cell growth. Although expressed in the ovary, the role of ADM in this organ is not clear. In the present study, ...
- Functional characterization of a synthetic abscisic acid analog with anti-inflammatory activity on human granulocytes and monocytes
[作者:Grozio, A; Millo, E; Guida, L; Vigliarolo, T; Bellotti, M; Salis, A; Fresia, C; Sturla, L; Magnone, M; Galatini, A; Damonte, G; De Flora, A; Bruzzone, S; Bagnasco, L; Zocchi, E,期刊:Biochemical and Biophysical Research Communications, 页码:696-701 , 文章类型: Article,,卷期:2011年415-4]
- The phytohormone abscisic acid (ABA), in addition to regulating several important physiological functions in plants, is also produced and released by human granulocytes and monocytes where it stimulates cell activities i...
- Cdc20 mediates D-box-dependent degradation of Sp100
[作者:Wang, R; Li, KM; Zhou, CH; Xue, JL; Ji, CN; Chen, JZ,期刊:Biochemical and Biophysical Research Communications, 页码:702-706 , 文章类型: Article,,卷期:2011年415-4]
- Cdc20 is a co-activator of the anaphase-promoting complex/cyclosome (APC/C complex), which recruits substrates at particular phases of the cell cycle and mediates their degradation. Sp100 is a PML-NB scaffold protein, wh...
- Basophil-derived mouse mast cell protease 11 induces microvascular leakage and tissue edema in a mast cell-independent manner
[作者:Yamagishi, H; Mochizuki, Y; Hamakubo, T; Obata, K; Ugajin, T; Sato, S; Kawano, Y; Minegishi, Y; Karasuyama, H,期刊:Biochemical and Biophysical Research Communications, 页码:709-713 , 文章类型: Article,,卷期:2011年415-4]
- Mouse mast cell protease 11 (mMCP-11) is the most recently identified member of the mouse mast cell tryptase family. This tryptase is preferentially produced by basophils in contrast to other members that are expressed b...
- Potent and selective inhibition of hepatitis C virus replication by novel phenanthridinone derivatives
[作者:Salim, MTA; Aoyama, H; Sugita, K; Watashi, K; Wakita, T; Hamasaki, T; Okamoto, M; Urata, Y; Hashimoto, Y; Baba, M,期刊:Biochemical and Biophysical Research Communications, 页码:714-719 , 文章类型: Article,,卷期:2011年415-4]
- A number of novel phenanthridinone derivatives were examined for their inhibitory effect on hepatitis C virus (HCV) replication in Huh-7 cells harboring self-replicating subgenomic viral RNA replicons with a luciferase r...
- Breast cancer metastasis suppressor 1 (BRMS1) is destabilized by the Cul3-SPOP E3 ubiquitin ligase complex
[作者:Kim, B; Nam, HJ; Pyo, KE; Jang, MJ; Kim, IS; Kim, D; Boo, K; Lee, SH; Yoon, JB; Baek, SH; Kim, JH,期刊:Biochemical and Biophysical Research Communications, 页码:720-726 , 文章类型: Article,,卷期:2011年415-4]
- Breast cancer metastasis suppressor 1 (BRMS1) suppresses metastasis without affecting primary tumorigenesis. The regulatory mechanism of BRMS1 at the protein level has not been revealed until recently. Here, we found tha...
- IRS-2 deficiency in macrophages promotes their accumulation in the vascular wall
[作者:Mita, T; Azuma, K; Goto, H; Jin, WL; Arakawa, M; Nomiyama, T; Suzuki, R; Kubota, N; Tobe, K; Kadowaki, T; Fujitani, Y; Hirose, T; Kawamori, R; Watada, H,期刊:Biochemical and Biophysical Research Communications, 页码:545-550 , 文章类型: Article,,卷期:2011年415-4]
- The aim of this study was to investigate the role of insulin receptor substrate-2 (IRS-2) mediated signal in macrophages on the accumulation of macrophages in the vascular wall. Mice transplanted with IRS-2(-/-) bone mar...
- MicroRNA-34a regulates migration of chondroblast and IL-1 beta-induced degeneration of chondrocytes by targeting EphA5
[作者:Kim, D; Song, J; Kim, S; Chun, CH; Jin, EJ,期刊:Biochemical and Biophysical Research Communications, 页码:551-557 , 文章类型: Article,,卷期:2011年415-4]
- MicroRNAs function as an endogenous mode of fine gene regulation and have been implicated in multiple differentiation and developmental processes. In the present study, we investigated the role of miRNA-34 during chondro...
- Structure-activity relationship of T-cell receptors based on alanine scanning
[作者:Narimatsu, S; Yoshioka, Y; Morishige, T; Yao, XL; Tsunoda, S; Tsutsumi, Y; Nishimura, MI; Mukai, Y; Okada, N; Nakagawa, S,期刊:Biochemical and Biophysical Research Communications, 页码:558-562 , 文章类型: Article,,卷期:2011年415-4]
- T-cell receptors (TCR) recognize complexes between human leukocyte antigens (HLA) and peptides derived from intracellular proteins. Their therapeutic use for antigen targeting, however, has been hindered by the very low ...
- The hsa-miR-5787 represses cellular growth by targeting eukaryotic translation initiation factor 5 (eIF5) in fibroblasts
[作者:Yoo, H; Yoo, JK; Lee, J; Lee, DR; Ko, JJ; Oh, SH; Choo, YK; Kim, JK,期刊:Biochemical and Biophysical Research Communications, 页码:567-572 , 文章类型: Article,,卷期:2011年415-4]
- MicroRNAs (miRNAs) are small non-coding RNAs that regulate diverse biological processes. We cloned novel small RNA from human mesenchymal stem cells (hMSCs) and termed microRNA-5787 (hsa-miR-5787) that met the criteria f...
- Proteasome inhibitors induce apoptosis and reduce viral replication in primary effusion lymphoma cells
[作者:Saji, C; Higashi, C; Niinaka, Y; Yamada, K; Noguchi, K; Fujimuro, M,期刊:Biochemical and Biophysical Research Communications, 页码:573-578 , 文章类型: Article,,卷期:2011年415-4]
- Primary effusion lymphoma (PEL) is an aggressive neoplasm caused by Kaposi's sarcoma-associated herpesvirus (KSHV). This study provides evidence that proteasomal activity is required for both survival of PEL cells stably...
- Barrier characteristics of epithelial cultures modelling the airway and intestinal mucosa: A comparison
[作者:Vllasaliu, D; Fowler, R; Garnett, M; Eaton, M; Stolnik, S,期刊:Biochemical and Biophysical Research Communications, 页码:579-585 , 文章类型: Article,,卷期:2011年415-4]
- The barrier characteristics of polarized layers of Calu-3 and Caco-2 cell lines, as commonly used in vitro models of intestinal and airway mucosa, respectively, were investigated by assessing the translocation of model m...
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