- Translational regulation of lipoprotein lipase in adipocytes: depletion of cellular protein kinase C alpha activates binding of the C subunit of protein kinase A to the 3 '-untranslated region of the lipoprotein lipase mRNA
[作者：Unal, R; Pokrovskaya, I; Tripathi, P; Monia, BP; Kern, PA; Ranganathan, G,期刊：Biochemical Journal, 页码：315-322 , 文章类型： Article，,卷期：2008年413-2]
- Adipose LPL (lipoprotein lipase) plays an important role in regulating plasma triacylglycerols and lipid metabolism. We have previously demonstrated that PKC alpha (protein kinase C alpha) depletion inhibits LPL translat...
- High membrane potential promotes alkenal-induced mitochondrial uncoupling and influences adenine nucleotide translocase conformation
[作者：Azzu, V; Parker, N; Brand, MD,期刊：Biochemical Journal, 页码：323-332 , 文章类型： Article，,卷期：2008年413-2]
- Mitochondria generate reactive oxygen species, whose downstream lipid peroxidation products, such as 4-hydroxythonenal, induce uncoupling of oxidative phosphorylation by increasing proton leak through mitochondrial inner...
- Physiological heart activation by adrenaline involves parallel activation of ATP usage and supply
[作者：Korzeniewski, B; Deschodt-Arsac, V; Calmettes, G; Franconi, JM; Diolez, P,期刊：Biochemical Journal, 页码：343-347 , 文章类型： Article，,卷期：2008年413-2]
- During low-to-high work transition in adult mammalian heart in vivo the concentrations of free ADP, ATP, PCr (phosphocreatine), Pi and NADH are essentially constant, in striking contrast with skeletal muscle. The direct ...
- Ankyrin repeats-containing cofactors interact with ADA3 and modulate its co-activator function
[作者：Li, CW; Dinh, GK; Zhang, AH; Chen, JD,期刊：Biochemical Journal, 页码：349-357 , 文章类型： Article，,卷期：2008年413-2]
- ANCO (ankyrin repeats-containing cofactor)-1 and ANCO-2 are a family of unique transcriptional co-regulators with dual properties: they interact with both the co-activators and the co-repressors [Zhang, Yeung, Li, Tsai, ...
- Insulin action on glucose transporters through molecular switches, tracks and tethers
[作者：Zaid, H; Antonescu, CN; Randhawa, VK; Klip, A,期刊：Biochemical Journal, 页码：201-215 , 文章类型： Review，,卷期：2008年413-2]
- Glucose entry into muscle cells is precisely regulated by insulin, through recruitment of GLUT4 (glucose transporter-4) to the membrane of muscle and fat cells. Work done over more than two decades has contributed to map...
- Accumulation of free complex-type N-glycans in MKN7 and MKN45 stomach cancer cells
[作者：Ishizuka, A; Hashimto, Y; Naka, R; Kinoshita, M; Kakehi, K; Seino, J; Funakoshi, Y; Suzuki, T; Kameyama, A; Narimatsu, H,期刊：Biochemical Journal, 页码：227-237 , 文章类型： Article，,卷期：2008年413-2]
- During the N-glycosylation reaction, it has been shown that 'free' N-glycans are generated either from lipid-linked oligosaccharides or from misfolded glycoproteins. In both cases, occurrence of high mannose-type free gl...
- The Hsp40 family chaperone protein DnaJB6 enhances Schlafen1 nuclear localization which is critical for promotion of cell-cycle arrest in T-cells
[作者：Zhang, YF; Yang, ZM; Cao, YH; Zhang, SJ; Li, H; Huang, Y; Ding, YQ; Liu, XL,期刊：Biochemical Journal, 页码：239-250 , 文章类型： Article，,卷期：2008年413-2]
- Tight control of cell-cycle progression is critical for T-lymphocytes to function properly. Slfn1 (Schlafen1) has been reported to play an important role in the establishment and maintenance of quiescence in T-lymphocyte...
- Hepatocyte growth factor activator inhibitor-1 has a complex subcellular itinerary
[作者：Godiksen, S; Selzer-Plon, J; Pedersen, EDK; Abell, K; Rasmussen, HB; Szabo, R; Bugge, TH; Vogel, LK,期刊：Biochemical Journal, 页码：251-259 , 文章类型： Article，,卷期：2008年413-2]
- HAI-1 [HGF (hepatocyte growth factor) activator inhibitor-1] is a Kunitz-type transmembrane serine protease inhibitor that forms inhibitor complexes with the trypsin-like serine protease, matriptase. HAI-1 is essential f...
- Chaperone ligand-discrimination by the TPR-domain protein Tah1
[作者：Millson, SH; Vaughan, CK; Zhai, C; Ali, MMU; Panaretou, B; Piper, PW; Pearl, LH; Prodromou, C,期刊：Biochemical Journal, 页码：261-268 , 文章类型： Article，,卷期：2008年413-2]
- Tah1 [TPR (tetratricopeptide repeat)-containing protein associated with Hsp (heat-shock protein) 90] has been identified as a TPR-domain protein. TPR-domain proteins are involved in protein-protein interactions and a num...
- Sugar binding to recombinant wild-type and mutant glucokinase monitored by kinetic measurement and tryptophan fluorescence
[作者：Zelent, B; Odili, S; Buettger, C; Shiota, C; Grimsby, J; Taub, R; Magnuson, MA; Vanderkooi, JM; Matschinsky, FM,期刊：Biochemical Journal, 页码：269-280 , 文章类型： Article，,卷期：2008年413-2]
- Tryptophan fluorescence was used to study GK (glucokinase), an enzyme that plays a prominent role in glucose homoeostasis which, when inactivated or activated by mutations, causes diabetes mellitus or hypoglycaemia in hu...
- Conformation, catalytic site, and enzymatic mechanism of the PR10 allergen-related enzyme norcoclaurine synthase
[作者：Berkner, H; Schweimer, K; Matecko, I; Rosch, P,期刊：Biochemical Journal, 页码：281-290 , 文章类型： Article，,卷期：2008年413-2]
The enzyme NCS [(S)-norcoclaurine synthase; EC 4.2.1.78] found in the common meadow rue, Thalictrum flavum, and other plant species, is involved in the biosynthesis of BIAs (benzylisoquinoline alkaloids). This group o...
- Gatecholaminergic polymorphic ventricular tachycardia-related mutations R33Q and L167H alter calcium sensitivity of human cardiac calsequestrin
[作者：Valle, G; Galla, D; Nori, A; Priori, SG; Gyorke, S; De Filippis, V; Volpe, P,期刊：Biochemical Journal, 页码：291-303 , 文章类型： Article，,卷期：2008年413-2]
- Two missense mutations, R33Q and L167H, of hCASQ2 (human cardiac calsequestrin), a protein segregated to the lumen of the sarcoplasmic reticulum, are linked to the autosomal recessive form of CPVT (catecholaminergic poly...
- Membrane pore formation by pentraxin proteins from Limulus, the American horseshoe crab
[作者：Harrington, JM; Chou, HT; Gutsmann, T; Gelhaus, C; Stahlberg, H; Leippe, M; Armstrong, PB,期刊：Biochemical Journal, 页码：305-313 , 文章类型： Article，,卷期：2008年413-2]
- The pentraxins are a family of highly conserved plasma proteins of metazoans known to function in immune defence. The canonical members, C-reactive protein and serum amyloid P component, have been identified in arthropod...
|