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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共19条记录   Biliverdin reductase is a transporter of haem into the nucleus and is essential for regulation of HO-1 gene expression by haematin [作者：Tudor, C; Lerner-Marmarosh, N; Engelborghs, Y; Gibbs, PEM; Maines, MD,期刊：Biochemical Journal, 页码：405-416 , 文章类型： Article，,卷期：2008年413-3] hBVR (human biliverdin reductase) is an enzyme that reduces biliverdin (the product of haem oxygenases HO-1 and HO-2 activity) to the antioxidant bilirubin. It also functions as a kinase and as a transcription factor in ... Insights into the substrate specificity of plant peptide deformylase, an essential enzyme with potential for the development of novel biotechnology applications in agriculture [作者：Dirk, LMA; Schmidt, JJ; Cai, Y; Barnes, JC; Hanger, KM; Nayak, NR; Williams, MA; Grossman, RB; Houtz, RL; Rodgers, DW,期刊：Biochemical Journal, 页码：417-427 , 文章类型： Article，,卷期：2008年413-3] The crystal structure of AtPDF1B [Arabidopsis thaliana PDF (peptide deformylase) 1B; EC 3.5.1.88], a plant specific deformylase, has been determined at a resolution of 2.4 angstrom (1 angstrom=0.1 nm). The overall fold o... Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies [作者：Zeng, Y; Sankala, H; Zhang, XX; Graves, PR,期刊：Biochemical Journal, 页码：429-436 , 文章类型： Article，,卷期：2008年413-3] Ago (Argonaute) proteins are essential effectors of RNA-mediated gene silencing. To explore potential regulatory mechanisms for Ago proteins, we examined the phosphorylation of human Ago2. We identified serine-387 as the... Increasing the expression of calcium-permeable TRPC3 and TRPC7 channels enhances constitutive secretion [作者：Lavender, V; Chong, S; Ralphs, K; Wolstenholme, AJ; Reaves, BJ,期刊：Biochemical Journal, 页码：437-446 , 文章类型： Article，,卷期：2008年413-3] The hTRPC [human TRPC (canonical transient receptor potential)] family of non-selective cation channels is proposed to mediate calcium influx across the plasma membrane via PLC (phospholipase C)-coupled receptors. Hetero... Biochemical function of typical and variant Arabidapsis thaliana U-box E3 ubiquitin-protein ligases [作者：Wiborg, J; O'Shea, C; Skriver, K,期刊：Biochemical Journal, 页码：447-457 , 文章类型： Article，,卷期：2008年413-3] The variance of the U-box domain in 64 Arabidopsis thaliana (thale cress) E3s (ubiquitin-protein ligases) was used to examine the interactions between E3s and E2s (ubiquitin-conjugating enzymes). E2s and E3s are componen... The cross-talk between NF-kappa B and HIF-1: further evidence for a significant liaison (vol 412, pg e17, 2008) [作者：Gorlach, A; Bonello, S,期刊：Biochemical Journal, 页码：571-571 , 文章类型： Correction，,卷期：2008年413-3] High Cu(I) and low proton affinities of the CXXC motif of Bacillus subtilis CopZ [作者：Zhou, L; Singleton, C; Le Brun, NE,期刊：Biochemical Journal, 页码：459-465 , 文章类型： Article，,卷期：2008年413-3] CopZ, an Atx I-like copper chaperone from the bacterium Bacillus subtilis, functions as part of a complex cellular machinery for Cu(I) trafficking and detoxification, in which it interacts specifically with the transmemb... Endosomal compartment contributes to the propagation of CD95/Fas-mediated signals in type II cells [作者：Matarrese, P; Manganelli, V; Garofalo, T; Tinari, A; Gambardella, L; Ndebele, K; Khosravi-Far, R; Soricie, M; Espost, MD; Malorni, W,期刊：Biochemical Journal, 页码：467-478 , 文章类型： Article，,卷期：2008年413-3] Participation of diverse organelles in the intracellular signalling that follows CD95/Fas receptor ligation encompasses a series of subcellular changes that are mandatory for, or even bolster, the apoptotic cascade. In t... S-nitrosylation of syntaxin 1 at Cys(145) is a regulatory switch controlling Munc18-1 binding [作者：Palmer, ZJ; Duncan, RR; Johnson, JR; Lian, LY; Mello, LV; Booth, D; Barclay, JW; Graham, ME; Burgoyne, RD; Prior, IA; Morgan, A,期刊：Biochemical Journal, 页码：479-491 , 文章类型： Article，,卷期：2008年413-3] Exocytosis is regulated by NO in many cell types, including neurons. In the present study we show that syntaxin la is a substrate for S-nitrosylation and that NO disrupts the binding of Munc18-1 to the closed conformatio... Reduction of S-nitrosoglutathione by alcohol dehydrogenase 3 is facilitated by substrate alcohols via direct cofactor recycling and leads to GSH-controlled formation of glutathione transferase inhibitors [作者：Staab, CA; Alander, J; Brandt, M; Lengqvist, J; Morgenstern, R; Grafstrom, RC; Hoog, JO,期刊：Biochemical Journal, 页码：493-504 , 文章类型： Article，,卷期：2008年413-3] GSNO (S-nitrosoglutathione) is emerging as a key regulator in NO signalling as it is in equilibrium with S-nitrosated proteins. Accordingly, it is of great interest to investigate GSNO metabolism in terms of competitive ... Association of human DNA helicase RecQ5 beta with RNA polymerase II and its possible role in transcription [作者：Izumikawa, K; Yanagida, M; Hayano, T; Tachikawa, H; Komatsu, W; Shimamoto, A; Futami, K; Furuichi, Y; Shinkawa, T; Yamauchi, Y; Isobe, T; Takahashi, N,期刊：Biochemical Journal, 页码：505-516 , 文章类型： Article，,卷期：2008年413-3] Although RecQ5 beta is a ssDNA (single-stranded DNA)-stimulated ATPase and an ATP-dependent DNA helicase with strand-annealing activities, its cellular function remains to be explored. In the present paper, we used immun... Elimination of competing hydrolysis and coupling side reactions of a cyclodextrin glucanotransferase by directed evolution [作者：Kelly, RM; Leemhuis, H; Rozeboom, HJ; van Oosterwijk, N; Dijkstra, BW; Dijkhuizen, L,期刊：Biochemical Journal, 页码：517-525 , 文章类型： Article，,卷期：2008年413-3] Thermoanaerobacterium thermosulfurigenes cyclodextrin glucanotransferase primarily catalyses the formation of cyclic alpha-(1,4)-linked oligosaccharides (cyclodextrins) from starch. This enzyme also possesses unusually h... Functional characterization of ribosomal P1/P2 proteins in human cells [作者：Martinez-Azorin, F; Remacha, M; Ballesta, JPG,期刊：Biochemical Journal, 页码：527-534 , 文章类型： Article，,卷期：2008年413-3] The 'stalk' is a large ribosomal subunit domain that regulates translation. In the present study the role of the ribosomal stalk P proteins in modulating ribosomal activity has been investigated in human cells using RNA ... Analysis of mutant origin recognition complex with reduced ATPase activity in vivo and in vitro [作者：Takehara, M; Makise, M; Takenaka, H; Asano, T; Mizushima, T,期刊：Biochemical Journal, 页码：535-543 , 文章类型： Article，,卷期：2008年413-3] In eukaryotes, ORC (origin recognition complex), a six-protein complex, is the most likely initiator of chromosomal DNA replication. ORC belongs to the AAA(+) (ATPases associated with a variety of cellular activities) fa... Proteomic analysis of polymeric salivary mucins: no evidence for MUC19 in human saliva [作者：Rousseau, K; Kirkham, S; Johnson, L; Fitzpatrick, B; Howard, M; Adams, EJ; Rogers, DF; Knight, D; Clegg, P; Thornton, DJ,期刊：Biochemical Journal, 页码：545-552 , 文章类型： Article，,卷期：2008年413-3] MUC5B is the predominant polymeric mucin in human saliva [Thornton, Khan, Mehrotra, Howard, Veerman, Packer and Sheehan (1999) Glycobiology 9, 293-302], where it contributes to oral cavity hydration and protection. More ... Identification of an iron-hepcidin complex [作者：Farnaud, S; Rapisarda, C; Bui, T; Drake, A; Cammack, R; Evans, RW,期刊：Biochemical Journal, 页码：553-557 , 文章类型： Article，,卷期：2008年413-3] Following its identification as a liver-expressed antimicrobial peptide, the hepcidin peptide was later shown to be a key player in iron homoeostasis. It is now proposed to be the 'iron hormone' which, by interacting wit...