- The Leishmania infantum cytosolic SIR2-related protein 1 (LiSIR2RP1) is an NAD(+)-dependent deacetylase and ADP-ribosyltransferase
[作者：Tavares, J; Ouaissi, A; Santarem, N; Sereno, D; Vergnes, B; Sampaio, P; Cordeiro-Da-Silva, A,期刊：Biochemical Journal, 页码：377-386 , 文章类型： Article，,卷期：2008年415-3]
- Proteins of the SIR2 (Silent Information Regulator 2) family are characterized by a conserved catalytic domain that exerts unique NAD+-dependent deacetylase activity on histones and various other cellular substrates. Pre...
- Structure-function analysis of plant aquaporin AtPIP2;1 gating by divalent cations and protons
[作者：Verdoucq, L; Grondin, A; Maurel, C,期刊：Biochemical Journal, 页码：409-416 , 文章类型： Article，,卷期：2008年415-3]
- Water channel proteins, AQPs (aquaporins), of the PIP (plasma membrane intrinsic protein) subfamily, provide a means for fine and quick adjustments of the plant water status. A molecular model for gating of PIPs by cytos...
- Probing the interaction of tetraspanin CD151 with integrin alpha 3 beta 1 using a panel of monoclonal antibodies with distinct reactivities toward the CD151-integrin alpha 3 beta 1 complex
[作者：Yamada, M; Tamura, Y; Sanzen, N; Sato-Nishiuchi, R; Hasegawa, H; Ashman, LK; Rubinstein, E; Yanez-Mo, M; Sanchez-Madrid, F; Sekiguchi, K,期刊：Biochemical Journal, 页码：417-427 , 文章类型： Article，,卷期：2008年415-3]
- CD 151, a member of the tetraspanin family of proteins, forms a stable complex with integrin alpha 3 beta 1 and regulates integrin-mediated cell-substrate adhesion. However, the molecular basis of the stable association ...
- Phospholipase C delta 1 regulates cell proliferation and cell-cycle progression from G(1)-to S-phase by control of cyclin E-CDK2 activity
[作者：Kaproth-Joslin, KA; Li, XQ; Reks, SE; Kelley, GG,期刊：Biochemical Journal, 页码：439-448 , 文章类型： Article，,卷期：2008年415-3]
- In the present study, we examined the role of PLC delta 1 (phospholipase C delta) in the regulation Of Cellular proliferation. We demonstrate that RNAi (RNA interference)-mediated knockdown of endogenous PLC delta 1, but...
- Ypp1/YGR198w plays an essential role in phosphoinositide signalling at the plasma membrane
[作者：Zhai, C; Li, KY; Markaki, V; Phelan, JP; Bowers, K; Cooke, FT; Panaretou, B,期刊：Biochemical Journal, 页码：455-466 , 文章类型： Article，,卷期：2008年415-3]
- Phosphoinositide signalling through the eukaryotic plasma membrane makes essential contributions to many processes, including remodelling of the actin cytoskeleton, vesicle trafficking and signalling from the cell surfac...
- Characterization of the DNA-binding motif of the arsenic-responsive transcription factor Yap8p
[作者：Ilina, Y; Sloma, E; Maciaszczyk-Dziubinska, E; Novotny, M; Thorsen, M; Wysocki, R; Tamas, MJ,期刊：Biochemical Journal, 页码：467-475 , 文章类型： Article，,卷期：2008年415-3]
- Saccharomyces cerevisiae uses several mechanisms for arsenic detoxification including the arsenate reductase Acr2p and the arsenite efflux protein Acr3p. ACR2 and ACR3 are transcribed in opposite directions from the same...
- Chromium(VI) inhibits mouse metallothionein-I gene transcription by preventing the zinc-dependent formation of an MTF-1-p300 complex
[作者：Kimura, T; Li, Y; Okumura, F; Itoh, N; Nakanishi, T; Sone, T; Isobe, M; Andrews, GK,期刊：Biochemical Journal, 页码：477-482 , 文章类型： Article，,卷期：2008年415-3]
- Mouse MT-I (metallothionein-1) transcription is regulated by MTF-1 (metal-response-element-binding transcription factor-1) which is recruited to the promoter in response to zinc. Cr(VI) [chromium(VI)] pretreatment blocks...
- Salt-stress-induced association of phosphatidylinositol 4,5-bisphosphate with clathrin-coated vesicles in plants
[作者：Konig, S; Ischebeck, T; Lerche, J; Stenzel, I; Heilmann, I,期刊：Biochemical Journal, 页码：387-399 , 文章类型： Article，,卷期：2008年415-3]
- Plants exposed to hyperosmotic stress undergo changes in membrane dynamics and lipid composition to maintain cellular integrity and avoid membrane leakage. Various plant species respond to hyperosmotic stress with transi...
- Depletion of nucleophosmin leads to distortion of nucleolar and nuclear structures in HeLa cells
[作者：Amin, MA; Matsunaga, S; Uchiyama, S; Fukui, K,期刊：Biochemical Journal, 页码：345-351 , 文章类型： Article，,卷期：2008年415-3]
- NPM (nucleophosmin; also known as B23) is an abundantly and ubiquitously expressed multifunctional nucleolar phosphoprotein, which is involved in numerous cellular processes, including ribosome biogenesis, protein chaper...
- The selectivity of inhibitors of protein kinase CK2: an update
[作者：Pagano, MA; Bain, J; Kazimierczuk, Z; Sarno, S; Ruzzene, M; Di Maira, G; Elliott, M; Orzeszko, A; Cozza, G; Meggio, F; Pinna, LA,期刊：Biochemical Journal, 页码：353-365 , 文章类型： Article，,卷期：2008年415-3]
- CK2 (casein kinase 2) is a very pleiotropic serine/threonine protein kinase whose abnormally high constitutive activity has often been correlated to pathological conditions with special reference to neoplasia. The two mo...
- Positional-scanning fluorigenic substrate libraries reveal unexpected specificity determinants of DUBs (deubiquitinating enzymes)
[作者：Drag, M; Mikolajczyk, J; Bekes, M; Reyes-Turcu, FE; Ellman, JA; Wilkinson, KD; Salvesen, GS,期刊：Biochemical Journal, 页码：367-375 , 文章类型： Article，,卷期：2008年415-3]
- DUBs (deubiquitinating enzymes) are a family of proteases responsible for the specific removal of ubiquitin attached to target proteins and thus control the free cellular pools of this molecule. DUB activity is Usually a...
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