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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共17条记录   Tetrahydrobiopterin: biochemistry and pathophysiology [作者：Werner, ER; Blau, N; Thoeny, B,期刊：Biochemical Journal, 页码：397-414 , 文章类型： Review，,卷期：2011年438-3] BH(4) (6R-L-erythro-5,6,7,8-tetrahydrobiopterin) is an essential cofactor of a set of enzymes that are of central metabolic importance, including four aromatic amino acid hydroxylases, alkylglycerol mono-oxygenase and th... Aggregation of amyloids in a cellular context: modelling and experiment [作者：Friedman, R,期刊：Biochemical Journal, 页码：415-426 , 文章类型： Review，,卷期：2011年438-3] Amyloid-related diseases are a group of illnesses in which an abnormal accumulation of proteins into fibrillar structures is evident. Results from a wide range of studies, ranging from identification of amyloid-beta dime... ACCELERATED PUBLICATION Novel regulation of PLC zeta activity via its XY-linker [作者：Nomikos, M; Elgmati, K; Theodoridou, M; Georgilis, A; Gonzalez-Garcia, JR; Nounesis, G; Swann, K; Lai, FA,期刊：Biochemical Journal, 页码：427-432 , 文章类型： Article，,卷期：2011年438-3] The XY-linker region of somatic cell PLC (phospholipase)-beta, -gamma, -delta and -epsilon isoforms confers potent catalytic inhibition, suggesting a common auto-regulatory role. Surprisingly, the sperm PLC zeta XY-linke... ACCELERATED PUBLICATION The mitochondrial citrate carrier: a new player in inflammation [作者：Infantino, V; Convertini, P; Cucci, L; Panaro, MA; Di Noia, MA; Calvello, R; Palmieri, F; Iacobazzi, V,期刊：Biochemical Journal, 页码：433-436 , 文章类型： Article，,卷期：2011年438-3] The mitochondrial CIC (citrate carrier) catalyses the efflux of citrate from the mitochondrial matrix in exchange for cytosolic malate. In the present paper we show that CIC mRNA and protein markedly increase in lipopoly... Drosophila Sal and Salr are transcriptional repressors [作者：Sanchez, J; Talamillo, A; Gonzalez, M; Sanchez-Pulido, L; Jimenez, S; Pirone, L; Sutherland, JD; Barrio, R,期刊：Biochemical Journal, 页码：437-445 , 文章类型： Article，,卷期：2011年438-3] The SALL (Spalt-like) family of zinc-finger transcription factors is conserved in metazoans. In Drosophila Sal (Spalt) and Salr (Spalt-related) control the expression of genes involved in wing and central nervous system ... Structural analysis of the Sil1-Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor [作者：Yan, M; Li, JZ; Sha, BD,期刊：Biochemical Journal, 页码：447-455 , 文章类型： Article，,卷期：2011年438-3] Sil1 functions as a NEF (nucleotide-exchange factor) for the ER (endoplasmic reticulum) Hsp70 (heat-shock protein of 70 kDa) Bip in eukaryotic cells. Sill may catalyse the ADP release from Bip by interacting directly wit... HIV-1 gp41 ectodomain enhances Cryptococcus neoformans binding to human brain microvascular endothelial cells via gp41 core-induced membrane activities [作者：Huang, SH; Wu, CH; Jiang, S; Bahner, I; Lossinsky, AS; Jong, AY,期刊：Biochemical Journal, 页码：457-466 , 文章类型： Article，,卷期：2011年438-3] Cryptococcus neoformans causes life-threatening meningoencephalitis, particularly prevalent in AIDS patients. The interrelationship between C. neoformans and HIV-1 is intriguing, as both pathogens elicit severe neuropath... Active-pocket size differentiating insectile from bacterial chitinolytic beta-N-acetyl-D-hexosaminidases [作者：Liu, T; Zhang, HT; Liu, FY; Chen, L; Shen, X; Yang, Q,期刊：Biochemical Journal, 页码：467-474 , 文章类型： Article，,卷期：2011年438-3] Chitinolytic beta-N-acetyl-D-hexosaminidase is a branch of the GH20 (glycoside hydrolase family 20) beta-N-acetyl-D-hexosaminidases that is only distributed in insects and micro-organisms, and is therefore a potential ta... A role for heparan sulfate proteoglycans in Plasmodium falciparum sporozoite invasion of anopheline mosquito salivary glands [作者：Armistead, JS; Wilson, IBH; van Kuppevelt, TH; Dinglasan, RR,期刊：Biochemical Journal, 页码：475-483 , 文章类型： Article，,卷期：2011年438-3] HS (heparan sulfate) has been shown to be an important mediator of Plasmodium sporozoite homing and invasion of the liver, but the role of this glycosaminoglycan in mosquito vector host-sporozoite interactions is unknown... New spectroscopic and electrochemical insights on a class I superoxide reductase: evidence for an intramolecular electron-transfer pathway [作者：Folgosa, F; Cordas, CM; Santos, JA; Pereira, AS; Moura, JJG; Tavares, P; Moura, I,期刊：Biochemical Journal, 页码：485-494 , 文章类型： Article，,卷期：2011年438-3] SORs (superoxide reductases) are enzymes involved in bacterial resistance to reactive oxygen species, catalysing the reduction of superoxide anions to hydrogen peroxide. So far three structural classes have been identifi... Monitoring protein-protein interactions in mammalian cells by trans-SUMOylation [作者：Srivastav, RK; Schwede, S; Klaus, M; Schwermann, J; Gaestel, M; Niedenthal, R,期刊：Biochemical Journal, 页码：495-503 , 文章类型： Article，,卷期：2011年438-3] Protein protein interactions are essential for almost all cellular processes, hence understanding these processes mainly depends on the identification and characterization of the relevant protein protein interactions. In... Interaction between bacterial outer membrane proteins and periplasmic quality control factors: a kinetic partitioning mechanism [作者：Wu, S; Ge, X; Lv, ZX; Zhi, ZY; Chang, ZY; Zhao, XS,期刊：Biochemical Journal, 页码：505-511 , 文章类型： Article，,卷期：2011年438-3] The OMPs (outer membrane proteins) of Gram-negative bacteria have to be translocated through the periplasmic space before reaching their final destination. The aqueous environment of the periplasmic space and high permea... Mechanistic studies on the enzymatic processing of fluorinated methionine analogues by Trichomonas vaginalis methionine gamma-Iyase [作者：Moya, IA; Westrop, GD; Coombs, GH; Honek, JF,期刊：Biochemical Journal, 页码：513-521 , 文章类型： Article，,卷期：2011年438-3] `TFM (L-trifluoromethionine), a potential prodrug, was reported to be toxic towards human pathogens that express MGL (L-methionine gamma-Iyase; EC 4.4.1.11), a pyridoxal phosphate-containing enzyme that converts L-methio... The role of the protein kinase A pathway in the response to alkaline pH stress in yeast [作者：Casado, C; Gonzalez, A; Platara, M; Ruiz, A; Arino, J,期刊：Biochemical Journal, 页码：523-533 , 文章类型： Article，,卷期：2011年438-3] Exposure of Saccharomyces cerevisiae to alkaline pH provokes a stress condition that generates a compensatory reaction. In the present study we examined a possible role for the PKA (protein kinase A) pathway in this resp... Site recognition and substrate screens for PKN family proteins [作者：Collazos, A; Michael, N; Whelan, RDH; Kelly, G; Mellor, H; Pang, LCH; Totty, N; Parker, PJ,期刊：Biochemical Journal, 页码：535-543 , 文章类型： Article，,卷期：2011年438-3] The PRKs [protein kinase C-related kinases; also referred to as PKNs (protein kinase Ns)] are a kinase family important in diverse functions including migration and cytokinesis. In the present study, we have re-evaluated... Divergent effect of mammalian PLC zeta in generating Ca(2+) oscillations in somatic cells compared with eggs [作者：Phillips, SV; Yu, YS; Rossbach, A; Nomikos, M; Vassilakopoulou, V; Livaniou, E; Cumbes, B; Lai, FA; George, CH; Swann, K,期刊：Biochemical Journal, 页码：545-553 , 文章类型： Article，,卷期：2011年438-3] Sperm PLC zeta (phospholipase CO zeta is a distinct phosphoinositide-specific PLC isoform that is proposed to be the physiological trigger of egg activation and embryo development at mammalian fertilization. Recombinant ...