- Prolonged expression of the gamma-H2AX DNA repair biomarker correlates with excess acute and chronic toxicity from radiotherapy treatment
[作者：Bourton, EC; Plowman, PN; Smith, D; Arlett, CF; Parris, CN,期刊：International Journal of Cancer, 页码：2928-2934 , 文章类型： Article，,卷期：2011年129-12]
- The normal tissue tolerance levels to fractionated radiotherapy have been appreciated by a century of careful clinical observations and radiobiological studies in animals. During clinical fractionated radiotherapy, these...
- Bezielle (BZL101)-induced oxidative stress damage followed by redistribution of metabolic fluxes in breast cancer cells: a combined proteomic and metabolomic study
[作者：Klawitter, J; Klawitter, J; Gurshtein, J; Corby, K; Fong, S; Tagliaferri, M; Quattrochi, L; Cohen, I; Shtivelman, E; Christians, U,期刊：International Journal of Cancer, 页码：2945-2957 , 文章类型： Article，,卷期：2011年129-12]
- Bezielle is an orally administered aqueous extract of Scutellaria barbata for treatment of advanced and metastatic breast cancer. Phase I trials showed promising tolerability and efficacy. In our study, we used a combine...
- Effects of small molecule inhibitors of PI3K/Akt/mTOR signaling on neuroblastoma growth in vitro and in vivo
[作者：Segerstrom, L; Baryawno, N; Sveinbjornsson, B; Wickstrom, M; Elfman, L; Kogner, P; Johnsen, JI,期刊：International Journal of Cancer, 页码：2958-2965 , 文章类型： Article，,卷期：2011年129-12]
- Activation of the PI3K/Akt signaling pathway is correlated with poor prognosis in neuroblastoma, the most common and deadly extracranial tumor of childhood. In this study, we show that the small-molecule inhibitors of ph...
- Male circumcision and anatomic sites of penile high-risk human papillomavirus in Rakai, Uganda
[作者：Tobian, AAR; Kong, XR; Gravitt, PE; Eaton, KP; Kigozi, G; Serwadda, D; Oliver, AE; Nalugoda, F; Makumbi, F; Chen, MZ; Wawer, MJ; Quinn, TC; Gray, RH,期刊：International Journal of Cancer, 页码：2970-2975 , 文章类型： Article，,卷期：2011年129-12]
- Male circumcision (MC) reduces penile high-risk human papillomavirus (HR-HPV) on the coronal sulcus and urethra. HR-HPV varies by anatomic site, and it is unknown whether MC decreases HR-HPV on the penile shaft. We asses...
- Transient gene silencing of galectin-3 suppresses pancreatic cancer cell migration and invasion through degradation of beta-catenin
[作者：Kobayashi, T; Shimura, T; Yajima, T; Kubo, N; Araki, K; Tsutsumi, S; Suzuki, H; Kuwano, H; Raz, A,期刊：International Journal of Cancer, 页码：2775-2786 , 文章类型： Article，,卷期：2011年129-12]
- Pancreatic cancer is a leading cause of cancer-related mortality and often has a poor prognosis because of its late diagnosis, aggressive local invasion, early metastasis and poor response to chemotherapy. The chemothera...
- Bfl-1 is a crucial pro-survival nuclear factor-kappa B target gene in Hodgkin/Reed-Sternberg cells
[作者：Loughran, ST; Campion, EM; D'Souza, BN; Smith, SM; Vrzalikova, K; Wen, KS; Murray, PG; Walls, D,期刊：International Journal of Cancer, 页码：2787-2796 , 文章类型： Article，,卷期：2011年129-12]
- Hodgkin/Reed-Sternberg (H/RS) cells are believed to represent clonal progeny of Germinal Centre B cells that have escaped negative selection by evading apoptosis. Aberrant constitutive activity of the transcription facto...
- MicroRNA miR-335 is crucial for the BRCA1 regulatory cascade in breast cancer development
[作者：Heyn, H; Engelmann, M; Schreek, S; Ahrens, P; Lehmann, U; Kreipe, H; Schlegelberger, B; Beger, C,期刊：International Journal of Cancer, 页码：2797-2806 , 文章类型： Article，,卷期：2011年129-12]
- The expression of microRNAs is altered in various cancer types, leading to their definition as onco- and tumor-suppressor microRNAs. In our study, we investigated the role of miR-335 in the formation of sporadic human br...
- VEGFR-2 expression in human melanoma: revised assessment
[作者：Molhoek, KR; Erdag, G; Rasamny, J; Murphy, C; Deacon, D; Patterson, JW; Slingluff, CL; Brautigan, DL,期刊：International Journal of Cancer, 页码：2807-2815 , 文章类型： Article，,卷期：2011年129-12]
- Vascular endothelial growth factor (VEGF) is an angiogenic factor that also functions as an autocrine growth factor for VEGF receptor (VEGFR)-2(+) melanomas. In multiple studies, VEGFR-2 was detected by immunostaining in...
- Evidences that the polymorphism Pro-282-Ala within the tumor suppressor gene WWOX is a new risk factor for differentiated thyroid carcinoma
[作者：Cancemi, L; Romei, C; Bertocchi, S; Tarrini, G; Spitaleri, I; Cipollini, M; Landi, D; Garritano, S; Pellegrini, G; Cristaudo, A; Pinchera, A; Barale, R; Elisei, R; Landi, S; Gemignani, F,期刊：International Journal of Cancer, 页码：2816-2824 , 文章类型： Article，,卷期：2011年129-12]
- We report a hypothesis-driven study aimed to detect genetic markers of susceptibility to differentiated thyroid carcinomas (DTC). A large number of candidate genes were first selected through literature search (genome-wi...
- A phase I study of vaccination with NY-ESO-1f peptide mixed with Picibanil OK-432 and Montanide ISA-51 in patients with cancers expressing the NY-ESO-1 antigen
[作者：Kakimi, K; Isobe, M; Uenaka, A; Wada, H; Sato, E; Doki, Y; Nakajima, J; Seto, Y; Yamatsuji, T; Naomoto, Y; Shiraishi, K; Takigawa, N; Kiura, K; Tsuji, K; Iwatsuki, K; Oka, M; Pan, L; Hoffman, EW; Old, LJ; Nakayama, E,期刊：International Journal of Cancer, 页码：2836-2846 , 文章类型： Article，,卷期：2011年129-12]
- We conducted a phase I clinical trial of a cancer vaccine using a 20-mer NY-ESO-1f peptide (NY-ESO-1 91-110) that includes multiple epitopes recognized by antibodies, and CD4 and CD8 T cells. Ten patients were immunized ...
- Identifying and characterizing "escapes''-men who develop metastases or die from prostate cancer despite screening (ERSPC, section Rotterdam)
[作者：Zhu, XY; van Leeuwen, PJ; Bul, M; Bangma, CH; Roobol, MJ; Schroder, FH,期刊：International Journal of Cancer, 页码：2847-2854 , 文章类型： Article，,卷期：2011年129-12]
- We aim to identify and characterize "escapes,'' men who developed metastasis and/or died from prostate cancer (PCa) despite screening, in the framework of the novel international ESCAPE-project. With this knowledge, the ...
- Identification and validation of highly frequent CpG island hypermethylation in colorectal adenomas and carcinomas
[作者：Oster, B; Thorsen, K; Lamy, P; Wojdacz, TK; Hansen, LL; Birkenkamp-Demtroder, K; Sorensen, KD; Laurberg, S; Omtoft, TF; Andersen, CL,期刊：International Journal of Cancer, 页码：2855-2866 , 文章类型： Article，,卷期：2011年129-12]
- In our study, whole-genome methylation arrays were applied to identify novel genes with tumor specific DNA methylation of promoter CpG islands in pre-malignant and malignant colorectal lesions. Using a combination of Ill...
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