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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共25条记录   Regulatory BCL2 promoter polymorphism (-938C > A) is associated with adverse outcome in patients with prostate carcinoma [作者：Bachmann, HS; Heukamp, LC; Schmitz, KJ; Hilburn, CF; Kahl, P; Buettner, R; Nuckel, H; Eisenhardt, A; Rubben, H; Schmid, KW; Siffert, W; Eggert, A; Schramm, A; Schulte, JH,期刊：International Journal of Cancer, 页码：2390-2399 , 文章类型： Article，,卷期：2011年129-10] Molecular markers predictive of prostate cancer prognosis are urgently needed. Overexpression of the antiapoptotic protein, Bcl-2, has repeatedly been shown to be associated with adverse outcome in this malignancy. We hy... Genome-wide linkage scan for prostate cancer susceptibility in Finland: evidence for a novel locus on 2q37.3 and confirmation of signal on 17q21-q22 [作者：Cropp, CD; Simpson, CL; Wahlfors, T; Ha, N; George, A; Jones, MS; Harper, U; Ponciano-Jackson, D; Green, TA; Tammela, TLJ; Bailey-Wilson, J; Schleutker, J,期刊：International Journal of Cancer, 页码：2400-2407 , 文章类型： Article，,卷期：2011年129-10] Genome-wide linkage studies have been used to localize rare and highly penetrant prostate cancer (PRCA) susceptibility genes. Linkage studies performed in different ethnic backgrounds and populations have been somewhat d... Lapatinib inhibits receptor phosphorylation and cell growth and enhances antibody-dependent cellular cytotoxicity of EGFR- and HER2-overexpressing esophageal cancer cell lines [作者：Mimura, K; Kono, K; Maruyama, T; Watanabe, M; Izawa, S; Shiba, S; Mizukami, Y; Kawaguchi, Y; Inoue, M; Kono, T; Choudhury, A; Kiessling, R; Fujii, H,期刊：International Journal of Cancer, 页码：2408-2416 , 文章类型： Article，,卷期：2011年129-10] Lapatinib is a dual tyrosine kinase inhibitor of the EGFR and HER2 tyrosine kinase domains. EGFR is expressed in 33.3% and HER2 in 30.3% of esophageal squamous cell carcinomas (ESCCs). To explore the potential utility of... CD103 is a hallmark of tumor-infiltrating regulatory T cells [作者：Anz, D; Mueller, W; Golic, M; Kunz, WG; Rapp, M; Koelzer, VH; Ellermeier, J; Ellwart, JW; Schnurr, M; Bourquin, C; Endres, S,期刊：International Journal of Cancer, 页码：2417-2426 , 文章类型： Article，,卷期：2011年129-10] Regulatory T cells (Treg) mediate tolerance towards self-antigens by suppression of innate and adaptive immunity. In cancer patients, tumor-infiltrating FoxP3+ Treg suppress local anti-tumor immune responses and are ofte... A MAGE-C2 antigenic peptide processed by the immunoproteasome is recognized by cytolytic T cells isolated from a melanoma patient after successful immunotherapy [作者：Ma, WB; Vigneron, N; Chapiro, J; Stroobant, V; Germeau, C; Boon, T; Coulie, PG; Van den Eynde, BJ,期刊：International Journal of Cancer, 页码：2427-2434 , 文章类型： Article，,卷期：2011年129-10] We have pursued our analysis of a melanoma patient who showed almost complete tumor regression following vaccination with MAGE-A1 and MAGE-A3 antigens. We previously described high frequencies of tumor-specific CTL precu... Molecular markers of endometrial carcinoma detected in uterine aspirates [作者：Colas, E; Perez, C; Cabrera, S; Pedrola, N; Monge, M; Castellvi, J; Eyzaguirre, F; Gregorio, J; Ruiz, A; Llaurado, M; Rigau, M; Garcia, M; Ertekin, T; Montes, M; Lopez-Lopez, R; Carreras, R; Xercavins, J; Ortega, A; Maes, T; Rosell, E; Doll, A; Abal, M; Reventos, J; Gil-Moreno, A,期刊：International Journal of Cancer, 页码：2435-2444 , 文章类型： Article，,卷期：2011年129-10] Endometrial cancer (EC) is the most frequent of the invasive tumors of the female genital tract. Although usually detected in its initial stages, a 20% of the patients present with advanced disease. To date, no character... Cancer stem cells: A promising concept and therapeutic challenge [作者：Ho, A; Fusenig, N,期刊：International Journal of Cancer, 页码：2309-2309 , 文章类型： Editorial Material，,卷期：2011年129-10] Phenotypic plasticity and epithelial-mesenchymal transitions in cancer and normal stem cells? [作者：Scheel, C; Weinberg, RA,期刊：International Journal of Cancer, 页码：2310-2314 , 文章类型： Article，,卷期：2011年129-10] Cancer stem cells (CSCs) are similar to normal stem cells in their ability to self-renew and to generate large populations of more differentiated descendants. In contrast to the hierarchical organization that is presumed... The cancer stem cell niche-there goes the neighborhood? [作者：Cabarcas, SM; Mathews, LA; Farrar, WL,期刊：International Journal of Cancer, 页码：2315-2327 , 文章类型： Article，,卷期：2011年129-10] The niche is the environment in which stem cells reside and is responsible for the maintenance of unique stem cell properties such as self-renewal and an undifferentiated state. The heterogeneous populations which consti... Leukemia stem cells [作者：Buss, EC; Ho, AD,期刊：International Journal of Cancer, 页码：2328-2336 , 文章类型： Article，,卷期：2011年129-10] Leukemia stem cells (LSCs) might originate from malignant transformation of normal hematopoietic stem cells (HSCs), or alternatively, of progenitors in which the acquired mutations have re-installed a dysregulated self-r... Head neck squamous cell carcinoma c-Met(+) cells display cancer stem cell properties and are responsible for cisplatin-resistance and metastasis [作者：Sun, SY; Wang, ZL,期刊：International Journal of Cancer, 页码：2337-2348 , 文章类型： Article，,卷期：2011年129-10] c-Met, the tyrosine kinase receptor for hepatocyte growth factor, is overexpressed in a variety of tumors in which it plays a central role in malignant transformation. Although c-Met has also been determined to be a crit... Glutamate increases pancreatic cancer cell invasion and migration via AMPA receptor activation and Kras-MAPK signaling [作者：Herner, A; Sauliunaite, D; Michalski, CW; Erkan, M; De Oliveira, T; Abiatari, I; Kong, B; Esposito, I; Friess, H; Kleeff, J,期刊：International Journal of Cancer, 页码：2349-2359 , 文章类型： Article，,卷期：2011年129-10] Glutamate has been implicated in tumorigenesis through activation of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors (AMPAR). However, the function of a glutamate-to-AMPAR signal in pancreatic d... IGFBP-4 activates the Wnt/beta-catenin signaling pathway and induces M-CAM expression in human renal cell carcinoma [作者：Ueno, K; Hirata, H; Majid, S; Tabatabai, ZL; Hinoda, Y; Dahiya, R,期刊：International Journal of Cancer, 页码：2360-2369 , 文章类型： Article，,卷期：2011年129-10] The Wnt/beta-catenin signaling pathway is inactivated by Wnt antagonists in most cancers and IGFBP-4 is an antagonist of the Wnt/beta-catenin signaling pathway. However, the function of IGFBP-4 is not currently understoo... Apurinic/apyrimidinic endonuclease is inversely associated with response to radiotherapy in pediatric ependymoma [作者：Bobola, MS; Jankowski, PP; Gross, ME; Schwartz, J; Finn, LS; Blank, A; Ellenbogen, RG; Silber, JR,期刊：International Journal of Cancer, 页码：2370-2379 , 文章类型： Article，,卷期：2011年129-10] Apurinic/apyrimidinic endonuclease (Ap endo) is a key DNA repair activity that confers radiation resistance in human cells. Here we examined the association between Ap endo activity and response to radiotherapy in pediat... Implication of human nonmetastatic clone 23 Type 1 and its downstream gene lipocalin 2 in metastasis and patient's survival of cancer of uterine cervix [作者：Wang, PH; Ko, JL; Yang, SF; Lin, LY,期刊：International Journal of Cancer, 页码：2380-2389 , 文章类型： Article，,卷期：2011年129-10] Human nonmetastatic clone 23 Type 1 (nm23-H1) is demonstrated to have diverse roles in metastasis and survival for many cancers, which are probably caused via different impacts on its downstream genes. Our preliminary st... High expression of stratifin is a universal abnormality during the course of malignant progression of early-stage lung adenocarcinoma [作者：Shiba-Ishii, A; Kano, J; Morishita, Y; Sato, Y; Minami, Y; Noguchi, M,期刊：International Journal of Cancer, 页码：2445-2453 , 文章类型： Article，,卷期：2011年129-10] Adenocarcinoma in situ (AIS) of the lung has an extremely favorable prognosis, with a 5-year survival rate of 100%. However, early invasive adenocarcinoma (EIA) often has a fatal outcome. In this study, we compared the e...