- Sunbed use during adolescence and early adulthood is associated with increased risk of early-onset melanoma
[作者:Cust, AE; Armstrong, BK; Goumas, C; Jenkins, MA; Schmid, H; Hopper, JL; Kefford, RF; Giles, GG; Aitken, JF; Mann, GJ,期刊:International Journal of Cancer, 页码:2425-2435 , 文章类型: Article,,卷期:2011年128-10]
- Sunbed use is associated with increased risk of melanoma. Younger people might be more susceptible to the carcinogenic effects of ultraviolet radiation. We investigated the association between sunbed use and risk of earl...
- A higher detection rate for colorectal cancer and advanced adenomatous polyp for screening with immunochemical fecal occult blood test than guaiac fecal occult blood test, despite lower compliance rate. a prospective, controlled, feasibility study
[作者:Levi, Z; Birkenfeld, S; Vilkin, A; Bar-Chana, M; Lifshitz, I; Chared, M; Maoz, E; Niv, Y,期刊:International Journal of Cancer, 页码:2415-2424 , 文章类型: Article,,卷期:2011年128-10]
- Immunochemical fecal occult blood test (FIT) is a new colorectal cancer (CRC) screening method already recommended by the American screening guidelines. We aimed to test the feasibility of FIT as compared to guaiac fecal...
- Non-alcoholic fatty liver disease progresses to hepatocellular carcinoma in the absence of apparent cirrhosis
[作者:Ertle, J; Dechene, A; Sowa, JP; Penndorf, V; Herzer, K; Kaiser, G; Schlaak, JF; Gerken, G; Syn, WK; Canbay, A,期刊:International Journal of Cancer, 页码:2436-2443 , 文章类型: Article,,卷期:2011年128-10]
- Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in developed countries, and accumulating evidence suggests it as the hepatic manifestation of the metabolic syndrome (MS). Although the published...
- Long-term aspirin use and the risk of total, high-grade, regionally advanced and lethal prostate cancer in a prospective cohort of health professionals, 1988-2006
[作者:Dhillon, PK; Kenfield, SA; Stampfer, MJ; Giovannucci, EL,期刊:International Journal of Cancer, 页码:2444-2452 , 文章类型: Article,,卷期:2011年128-10]
- Experimental studies suggest a role for aspirin in the chemoprevention of prostate cancer and epidemiological evidence supports a modest inverse association between regular aspirin use and prostate cancer risk, especiall...
- Cilengitide inhibits progression of experimental breast cancer bone metastases as imaged noninvasively using VCT, MRI and DCE-MRI in a longitudinal in vivo study
[作者:Bauerle, T; Komljenovic, D; Merz, M; Berger, MR; Goodman, SL; Semmler, W,期刊:International Journal of Cancer, 页码:2453-2462 , 文章类型: Article,,卷期:2011年128-10]
- The aim of this study was to investigate the effect of inhibiting alpha(v)beta(3)/alpha(v)beta(5) integrins by cilengitide in experimentally induced breast cancer bone metastases using noninvasive imaging techniques. For...
- Nonsteroidal anti-inflammatory drugs do not interfere with imiquimod treatment for usual type vulvar intraepithelial neoplasia
[作者:Terlou, A; Kleinjan, A; Beckmann, I; Heijmans-Antonissen, C; van Seters, M; Santegoets, LAM; van Beurden, M; Helmerhorst, TJM; Blok, LJ,期刊:International Journal of Cancer, 页码:2463-2469 , 文章类型: Article,,卷期:2011年128-10]
- Imiquimod has been shown to be an effective treatment for usual type vulvar intraepithelial neoplasia (uVIN). Since local inflammation and burning are common side effects, patients often use nonsteroidal anti-inflammator...
- Cell-penetrating chitosan/doxorubicin/TAT conjugates for efficient cancer therapy
[作者:Lee, JY; Choi, YS; Suh, JS; Kwon, YM; Yang, VC; Lee, SJ; Chung, CP; Park, YJ,期刊:International Journal of Cancer, 页码:2470-2480 , 文章类型: Article,,卷期:2011年128-10]
- In this study, a cell-penetrating peptide, the transactivating transcriptional factor (TAT) domain from HIV, was linked to a chitosan/doxorubicin (chitosan/DOX) conjugate to form a chitosan/DOX/TAT hybrid. The synthesize...
- A water soluble parthenolide analog suppresses in vivo tumor growth of two tobacco-associated cancers, lung and bladder cancer, by targeting NF-kappa B and generating reactive oxygen species
[作者:Shanmugam, R; Kusumanchi, P; Appaiah, H; Cheng, LA; Crooks, P; Neelakantan, S; Peat, T; Klaunig, J; Matthews, W; Nakshatri, H; Sweeney, CJ,期刊:International Journal of Cancer, 页码:2481-2494 , 文章类型: Article,,卷期:2011年128-10]
- Dimethylaminoparthenolide (DMAPT) is a water soluble parthenolide analog with preclinical activity in hematologic malignancies. Using non-small lung cancer (NSCLC) cell lines (A549 and H522) and an immortalized human bro...
- Cigarette smoke induces promoter methylation of single-stranded DNA-binding protein 2 in human esophageal squamous cell carcinoma
[作者:Huang, YP; Chang, XF; Lee, JN; Cho, YG; Zhong, XL; Park, IS; Liu, JW; Califano, JA; Ratovitski, EA; Sidransky, D; Kim, MS,期刊:International Journal of Cancer, 页码:2261-2273 , 文章类型: Article,,卷期:2011年128-10]
- Esophageal squamous cell carcinoma (ESCC) is the sixth most frequent cause of cancer death in the world, and cigarette smoke is a key factor in esophageal carcinogenesis. To identify molecular changes during cigarette sm...
- Sustained NF-kappaB activity in chronic lymphocytic leukemia is independent of genetic and epigenetic alterations in the TNFAIP3 (A20) locus
[作者:Frenzel, LP; Claus, R; Plume, N; Schwamb, J; Konermann, C; Pallasch, CP; Claasen, J; Brinker, R; Wollnik, B; Plass, C; Wendtner, CM,期刊:International Journal of Cancer, 页码:2495-2500 , 文章类型: Article,,卷期:2011年128-10]
- Inappropriate nuclear factor (NF) kappa B activity is one major hallmark of B-cell malignancies and chronic lymphocytic leukemia (CLL). NF kappa B-dependent genes are involved in antiapoptosis, cell proliferation and met...
- Specific infiltration of langerin-positive dendritic cells in EBV-infected tonsil, Hodgkin lymphoma and nasopharyngeal carcinoma
[作者:Braz-Silva, PH; Vitale, S; Butori, C; Guevara, N; Santini, J; Magalhaes, M; Hofman, P; Doglio, A,期刊:International Journal of Cancer, 页码:2501-2508 , 文章类型: Article,,卷期:2011年128-10]
- We report here the existence of a novel subset of langerin (CD207)-positive, immature dendritic cells (DCs) (CD83(neg)) abundantly infiltrating Epstein Barr virus (EBV)-infected areas in tonsil, Hodgkin lymphoma and naso...
- MiR-125b targets BCL3 and suppresses ovarian cancer proliferation
[作者:Guan, Y; Yao, HL; Zheng, ZH; Qiu, GR; Sun, KL,期刊:International Journal of Cancer, 页码:2274-2283 , 文章类型: Article,,卷期:2011年128-10]
- Micro-RNAs (miRNAs) important for post-transcriptional gene expression as negative regulators are endogenous 21- to 23-nucleotide noncoding RNAs. Many miRNAs are expressed in ovarian cancer (OC). In this study, we report...
- Silencing of the SEC62 gene inhibits migratory and invasive potential of various tumor cells
[作者:Greiner, M; Kreutzer, B; Jung, V; Grobholz, R; Hasenfus, A; Stohr, RF; Tornillo, L; Dudek, J; Stockle, M; Unteregger, G; Kamradt, J; Wullich, B; Zimmermann, R,期刊:International Journal of Cancer, 页码:2284-2295 , 文章类型: Article,,卷期:2011年128-10]
- Sec62 is part of the protein translocation apparatus in the membrane of the endoplasmic reticulum (ER). In yeast, Sec62 participates in the post-translational translocation of proteins into the ER, but its function in ma...
- Genome-wide DNA methylation analysis of neuroblastic tumors reveals clinically relevant epigenetic events and large-scale epigenomic alterations localized to telomeric regions
[作者:Buckley, PG; Das, S; Bryan, K; Watters, KM; Alcock, L; Koster, J; Versteeg, R; Stallings, RL,期刊:International Journal of Cancer, 页码:2296-2305 , 文章类型: Article,,卷期:2011年128-10]
- The downregulation of specific genes through DNA hypermethylation is a major hallmark of cancer, although the extent and genomic distribution of hypermethylation occurring within cancer genomes is poorly understood. We r...
- Norepinephrine induces VEGF expression and angiogenesis by a hypoxia-inducible factor-1 alpha protein-dependent mechanism
[作者:Park, SY; Kang, JH; Jeong, KJ; Lee, J; Han, JW; Choi, WS; Kim, YK; Kang, J; Park, CG; Lee, HY,期刊:International Journal of Cancer, 页码:2306-2316 , 文章类型: Article,,卷期:2011年128-10]
- A growing number of studies have demonstrated that physiological factors can influence the progression of several cancers via cellular immune function, angiogenesis and metastasis. Recently, stress-induced catecholamines...
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