- NANOG is a direct target of TGF beta/Activin-mediated SMAD signaling in human ESCs
[作者:Xu, RH; Sampsell-Barron, TL; Gu, F; Root, S; Peck, RM; Pan, GJ; Yu, JY; Antosiewicz-Bourget, J; Tian, SL; Stewart, R; Thomson, JA,期刊:Cell Stem Cell, 页码:196-206 , 文章类型: Article,,卷期:2008年3-2]
- Self-renewal of human embryonic stem cells (ESCs) is promoted by FGF and TGF beta/Activin signaling, and differentiation is promoted by BMP signaling, but how these signals regulate genes critical to the maintenance of p...
- Evi-1 is a critical regulator for hematopoietic stem cells and transformed leukemic cells
[作者:Goyama, S; Yamamoto, G; Shimabe, M; Sato, T; Ichikawa, M; Ogawa, S; Chiba, S; Kurokawa, M,期刊:Cell Stem Cell, 页码:207-220 , 文章类型: Article,,卷期:2008年3-2]
- Evi-1 has been recognized as one of the dominant oncogenes associated with murine and human myeloid leukemia. Here, we show that hematopoietic stem cells (HSCs) in Evi-1-deficient embryos are severely reduced in number w...
- Nf2/merlin regulates hematopoietic stem cell behavior by altering microenvironmental architecture
[作者:Larsson, J; Ohishi, M; Garrison, B; Aspling, M; Janzen, V; Adams, GB; Curto, M; McClatchey, AI; Schipani, E; Scadden, DT,期刊:Cell Stem Cell, 页码:221-227 , 文章类型: Article,,卷期:2008年3-2]
- Stem cell population size is highly regulated across species and tissue types, and alterations are associated with premature tissue failure or cancer. We assessed whether the tumor suppressor and mediator of cell contact...
- Uncapping the potential of renal stem cells
[作者:Quaggin, SE,期刊:Cell Stem Cell, 页码:123-124 , 文章类型: Article,,卷期:2008年3-2]
- In this issue of Cell Stem Cell, McMahon and coworkers (Kobayashi et al., 2008) characterize a subset of progenitor cells in the developing kidney. six2-expressing mesenchymal cells exhibit hallmark stem cell traits, in ...
- Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development
[作者:Kobayashi, A; Valerius, MT; Mugford, JW; Carroll, TJ; Self, M; Oliver, G; McMahon, AP,期刊:Cell Stem Cell, 页码:169-181 , 文章类型: Article,,卷期:2008年3-2]
- Nephrons, the basic functional units of the kidney, are generated repetitively during kidney organogenesis from a mesenchymal progenitor population. Which cells within this pool give rise to nephrons and how multiple nep...
- Wnt signaling promotes reprogramming of somatic cells to pluripotency
[作者:Marson, A; Foreman, R; Chevalier, B; Bilodeau, S; Kahn, M; Young, RA; Jaenisch, R,期刊:Cell Stem Cell, 页码:132-135 , 文章类型: Editorial Material,,卷期:2008年3-2]
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- New opportunities: The use of Nanotechnologies to manipulate and track stem cells
[作者:Ferreira, L; Karp, JM; Nobre, L; Langer, R,期刊:Cell Stem Cell, 页码:136-146 , 文章类型: Review,,卷期:2008年3-2]
- Nanotechnologies are emerging platforms that could be useful in measuring, understanding, and manipulating stem cells. Examples include magnetic nanoparticles and quantum dots for stem cell labeling and in vivo tracking;...
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