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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共15条记录   Hematopoietic Stem Cell Function and Survival Depend on c-Myc and N-Myc Activity [作者：Laurenti, E; Varnum-Finney, B; Wilson, A; Ferrero, I; Blanco-Bose, WE; Ehninger, A; Knoepfler, PS; Cheng, PF; MacDonald, HR; Eisenman, RN; Bernstein, ID; Trumpp, A,期刊：Cell Stem Cell, 页码：611-624 , 文章类型： Article，,卷期：2008年3-6] Myc activity is emerging as a key element in acquisition and maintenance of stem cell properties. We have previously shown that c-Myc deficiency results in accumulation of defective hematopoietic stem cells (HSCs) due to... Fate Tracing Reveals the Endothelial Origin of Hematopoietic Stem Cells [作者：Zovein, AC; Hofmann, JJ; Lynch, M; French, WJ; Turlo, KA; Yang, Y; Becker, MS; Zanetta, L; Dejana, E; Gasson, JC; Tallquist, MD; Iruela-Arispe, ML,期刊：Cell Stem Cell, 页码：625-636 , 文章类型： Article，,卷期：2008年3-6] Hematopoietic stem cells (HSCs) originate within the aortic-gonado-mesonephros (AGM) region of the midgestation embryo, but the cell type responsible for their emergence is unknown since critical hematopoietic factors ar... Human Embryonic Stem Cell-Derived Motor Neurons Are Sensitive to the Toxic Effect of Glial Cells Carrying an ALS-Causing Mutation [作者：Di Giorgio, FP; Boulting, GL; Bobrowicz, S; Eggan, KC,期刊：Cell Stem Cell, 页码：637-648 , 文章类型： Article，,卷期：2008年3-6] It has been proposed that human embryonic stem cells could be used to provide an inexhaustible supply of differentiated cell types for the study of disease processes. Although methods for differentiating embryonic stem c... Non-Cell-Autonomous Effect of Human SOD1(G37R) Astrocytes on Motor Neurons Derived from Human Embryonic Stem Cells [作者：Marchetto, MCN; Muotri, AR; Mu, YL; Smith, AM; Cezar, GG; Gage, FH,期刊：Cell Stem Cell, 页码：649-657 , 文章类型： Article，,卷期：2008年3-6] Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by motor neuron death. ALS can be induced by mutations in the superoxide dismutase 1 gene (SOD1). Evidence for the non-cell-autonomous natu... Nf1 Mutation Expands an EGFR-Dependent Peripheral Nerve Progenitor that Confers Neurofibroma Tumorigenic Potential [作者：Williams, JP; Wu, JQ; Johansson, G; Rizvi, TA; Miller, SC; Geiger, H; Malik, P; Li, WL; Mukouyama, YS; Cancelas, JA; Ratner, N,期刊：Cell Stem Cell, 页码：658-669 , 文章类型： Article，,卷期：2008年3-6] Defining growth factor requirements for progenitors facilitates their characterization and amplification. We characterize a peripheral nervous system embryonic dorsal root ganglion progenitor population using in vitro cl... Potency and Fate Specification in CNS Stem Cell Populations In Vitro [作者：Ravin, R; Hoeppner, DJ; Munno, DM; Carmel, L; Sullivan, J; Levitt, DL; Miller, JL; Athaide, C; Panchision, DM; Mckay, RDG,期刊：Cell Stem Cell, 页码：670-680 , 文章类型： Article，,卷期：2008年3-6] To realize the promise of stem cell biology, it is important to identify the precise time in the history of the cell when developmental potential is restricted. To achieve this goal, we developed a real-time imaging syst... Generation of Induced Pluripotent Stem Cells from Adult Rhesus Monkey Fibroblasts [作者：Liu, HS; Zhu, FF; Yong, J; Zhang, PB; Hou, PP; Li, HG; Jiang, W; Cai, J; Liu, M; Cui, K; Qu, XX; Xiang, TT; Lu, DY; Chi, XC; Gao, G; Ji, WZ; Ding, MX; Deng, HK,期刊：Cell Stem Cell, 页码：587-590 , 文章类型： Editorial Material，,卷期：2008年3-6] Stem Cell Clinics Online: The Direct-to-Consumer Portrayal of Stem Cell Medicine [作者：Lau, D; Ogbogu, U; Taylor, B; Stafinski, T; Menon, D; Caulfield, T,期刊：Cell Stem Cell, 页码：591-594 , 文章类型： Editorial Material，,卷期：2008年3-6] New ISSCR Guidelines Underscore Major Principles for Responsible Translational Stem Cell Research [作者：Hyun, I; Lindvall, O; Ahrlund-Richter, L; Cattaneo, E; Cavazzana-Calvo, M; Cossu, G; De Luca, M; Fox, IJ; Gerstle, C; Goldstein, RA; Hermeren, G; High, KA; Kim, HO; Lee, HP; Levy-Lahad, E; Li, L; Lo, B; Marshak, DR; Mcnab, A; Munsie, M; Nakauchi, H; Rao, M; Rooke, HM; Valles, CS; Srivastava, A; Sugarman, J; Taylor, PL; Veiga, A; Wong, AL; Zoloth, L; Daley, GQ,期刊：Cell Stem Cell, 页码：607-609 , 文章类型： Editorial Material，,卷期：2008年3-6] ALS Model Glia Can Mediate Toxicity to Motor Neurons Derived from Human Embryonic Stem Cells [作者：Hedlund, E; Isacson, O,期刊：Cell Stem Cell, 页码：575-576 , 文章类型： Review，,卷期：2008年3-6] In this issue of Cell Stem Cell, Di Giorgio et al. (2008) and Marchetto et al. (2008) culture motor neurons derived from human embryonic stem cells with astrocytes expressing mutant SOD1. In these human ALS models, motor... An EZ Mark to Miss [作者：Ho, L; Crabtree, GR,期刊：Cell Stem Cell, 页码：577-578 , 文章类型： Review，,卷期：2008年3-6] Ezh2, the m ethyl transferase within Polycomb Repressive II Complexes, was thought to be essential for all H3K27me3 marks in embryonic stem cells (ESCs). Recently in Molecular Cell, Shen and colleagues (2008) revealed th... Killer Granzyme B Linked to N-myc- and c-myc-Dependent HSC Survival: Isn't That Comyc? [作者：Sauvageau, G; Perreault, C,期刊：Cell Stem Cell, 页码：579-580 , 文章类型： Review，,卷期：2008年3-6] c-myc is a key regulator of hemopoietic stem cell (HSC) activity. In this issue of Cell Stem Cell, Laurenti et al. (2008) show that c-myc and N-myc control HSC survival and link this finding to the regulation of granzyme... Have Hair Follicle Stem Cells Shed Their Tranquil Image? [作者：Lin, KK; Andersen, B,期刊：Cell Stem Cell, 页码：581-582 , 文章类型： Review，,卷期：2008年3-6] In a recent issue of Nature Genetics, Jaks et al. (2008) demonstrate that hair follicle cells expressing the intestinal stem cell marker Lgr5 are hair follicle epithelial stem cells. In contrast to the established bulge ... Overcoming Obstacles in the Search for the Site of Hematopoietic Stem Cell Emergence [作者：Yoshimoto, M; Porayette, P; Yoder, MC,期刊：Cell Stem Cell, 页码：583-586 , 文章类型： Review，,卷期：2008年3-6] The murine embryo has become a valuable tool to examine the ontogeny of hematopoiesis. However, the onset of the systemic circulation has long been a confounding developmental variable that may mask the site of blood cel... Guidelines and Techniques for the Generation of Induced Pluripotent Stem Cells [作者：Maherali, N; Hochedlinger, K,期刊：Cell Stem Cell, 页码：595-605 , 文章类型： Review，,卷期：2008年3-6] Direct reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) provides an invaluable resource for regenerative medicine, enabling the generation of patient-specific cells of any lineage without the use ...