- Reduced Level of Smoothened Suppresses Intestinal Tumorigenesis by Down-Regulation of Wnt Signaling
[作者：Arimura, S; Matsunaga, A; Kitamura, T; Aoki, K; Aoki, M; Taketo, MM,期刊：Gastroenterology, 页码：629-638 , 文章类型： Article，,卷期：2009年137-2]
- BACKGROUND & AIMS: Although the Hedgehog (Hh) pathway regulates development and progression of several types of cancer, its involvement in colon cancer remains unclear. We aimed to clarify the roles of Hh signaling in in...
- Release of Endogenous Opioids From Duodenal Enteroendocrine Cells Requires Trpm5
[作者：Kokrashvili, Z; Rodriguez, D; Yevshayeva, V; Zhou, H; Margolskee, RF; Mosinger, B,期刊：Gastroenterology, 页码：598-606 , 文章类型： Article，,卷期：2009年137-2]
- BACKGROUND & AIMS: Enteroendocrine cells, the largest and most diverse population of mammalian endocrine cells, comprise a number of different cell types in the gut mucosa that produce, store, and secrete small molecules...
- Argon Plasma Coagulation of Cervical Heterotopic Gastric Mucosa as an Alternative Treatment for Globus Sensations
[作者：Bajbouj, M; Becker, V; Eckel, F; Miehlke, S; Pech, O; Prinz, C; Schmid, RM; Meining, A,期刊：Gastroenterology, 页码：440-444 , 文章类型： Article，,卷期：2009年137-2]
- BACKGROUND & AIMS: Ablation of gastric inlet patches (GIP) in the cervical esophagus by argon plasma coagulation (APC) can alleviate chronic globus sensations in the throat. We investigated the efficacy of this therapy i...
- Stem Cells and Liver Regeneration
[作者：Duncan, AW; Dorrell, C; Grompe, M,期刊：Gastroenterology, 页码：466-481 , 文章类型： Review，,卷期：2009年137-2]
- One of the defining features of the liver is the capacity to maintain a constant size despite injury. Although the precise molecular signals involved in the maintenance of liver size are not completely known, it is clear...
- Fecal Incontinence in US Adults: Epidemiology and Risk Factors
[作者：Whitehead, WE; Borrud, L; Goode, PS; Meikle, S; Mueller, ER; Tuteja, A; Weidner, A; Weinstein, M; Ye, W,期刊：Gastroenterology, 页码：512-517 , 文章类型： Article，,卷期：2009年137-2]
- BACKGROUND & AIMS: The study aims were to estimate the prevalence of different types and frequencies of fecal incontinence (FI), describe demographic factors, and identify risk factors. METHODS: The National Health and N...
- Time Trends in Therapies and Outcomes for Adult Inflammatory Bowel Disease, Northern California, 1998-2005
[作者：Herrinton, LJ; Liu, LY; Fireman, B; Lewis, JD; Allison, JE; Flowers, N; Hutfless, S; Velayos, FS; Abramson, O; Altschuler, A; Perry, GS,期刊：Gastroenterology, 页码：502-511 , 文章类型： Article，,卷期：2009年137-2]
- BACKGROUND & AIMS: The management of inflammatory bowel disease (IBD) has become 'increasingly complicated, and it is unknown whether poor outcomes (prolonged steroid use, hospitalizations, and surgery) have declined in ...
- Amphipathic DNA Polymers Inhibit Hepatitis C Virus Infection by Blocking Viral Entry
[作者：Matsumura, T; Hu, ZY; Kato, T; Dreux, M; Zhang, YY; Imamura, M; Hiraga, N; Juteau, JM; Cosset, FL; Chayama, K; Vaillant, A; Liang, TJ,期刊：Gastroenterology, 页码：673-681 , 文章类型： Article，,卷期：2009年137-2]
- BACKGROUND & AIMS: Hepatitis C virus (HCV) gains entry into susceptible cells by interacting with cell surface receptor(s). Viral entry is an attractive target for antiviral development because of the highly conserved me...
- ITF-2 Is Disrupted via Allelic Loss of Chromosome 18q21, and ITF-2B Expression Is Lost at the Adenoma-Carcinoma Transition
[作者：Herbst, A; Bommer, GT; Kriegl, L; Jung, A; Behrens, A; Csanadi, E; Gerhard, M; Bolz, C; Riesenberg, R; Zimmermann, W; Dietmaier, W; Wolf, I; Brabletz, T; Goke, B; Kolligs, FT,期刊：Gastroenterology, 页码：639-648 , 文章类型： Article，,卷期：2009年137-2]
- BACKGROUND & AIMS: The ubiquitously expressed basic helix-loop-helix transcription factor ITF-2B has an important role in differentiation processes, and its transcription is regulated by beta-catenin. The ITF-2 gene is l...
- Kupffer Cells Mediate Leptin-Induced Liver Fibrosis
[作者：Wang, JH; Leclercq, I; Brymora, JM; Xu, N; Ramezani-Moghadam, M; London, RM; Brigstock, D; George, J,期刊：Gastroenterology, 页码：713-723 , 文章类型： Article，,卷期：2009年137-2]
- BACKGROUND & AIMS: Leptin has profibrogenic effects in liver, although the mechanisms of this process are unclear. We sought to elucidate the direct and indirect effects of leptin on hepatic stellate cells (HSCs). METHOD...
- Microtome-Free 3-Dimensional Confocal Imaging Method for Visualization of Mouse Intestine With Subcellular-Level Resolution
[作者：Fu, YY; Lin, CW; Enikolopov, G; Sibley, E; Chiang, AS; Tang, SC,期刊：Gastroenterology, 页码：453-465 , 文章类型： Article，,卷期：2009年137-2]
- BACKGROUND & AIMS: The intrinsic opacity of mouse intestinal tissue prevents its evaluation by high-resolution, in-depth optical microscopy. Instead, intestinal tissue is usually sectioned to expose the interior domains ...
- High Incidence of Mortality and Recurrent Bleeding in Patients With Helicobacter pylori-Negative Idiopathic Bleeding Ulcers
[作者：Wong, GLH; Wong, VWS; Chan, YW; Ching, JYL; Au, K; Hui, AJ; Lai, LH; Chow, DKL; Siu, DKF; Lui, YN; Wu, JCY; To, KF; Hung, LCT; Chan, HLY; Sung, JJY; Chan, FKL,期刊：Gastroenterology, 页码：525-531 , 文章类型： Article，,卷期：2009年137-2]
- BACKGROUND & AIMS: The long-term prognosis of peptic ulcers associated with neither Helicobacter pylori nor nonsteroidal anti-inflammatory drugs (NSAIDs) is unknown. METHODS: This 7-year prospective cohort study recruite...
- Antidiabetic Therapies Affect Risk of Pancreatic Cancer
[作者：Li, DH; Yeung, SCJ; Hassan, MM; Konopleva, M; Abbruzzese, JL,期刊：Gastroenterology, 页码：482-488 , 文章类型： Article，,卷期：2009年137-2]
- BACKGROUND & AIMS: Antidiabetic drugs have been found to have various effects on cancer in experimental systems and in epidemiologic studies, although the association between these therapeutics and the risk of human panc...
- Convergence of Wnt Signaling on the HNF4 alpha-Driven Transcription in Controlling Liver Zonation
[作者：Colletti, M; Cicchini, C; Conigliaro, A; Santangelo, L; Alonzi, T; Pasquini, E; Tripodi, M; Amicone, L,期刊：Gastroenterology, 页码：660-672 , 文章类型： Article，,卷期：2009年137-2]
- BACKGROUND & AIMS: In each heparocyte, the specific repertoire of gene expression is influenced by its exact location along the portocentrovenular axis of the hepatic lobule and provides a reason for the liver functions ...
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