- Liver Zonation Occurs Through a beta-Catenin-Dependent, c-Myc-Independent Mechanism
[作者：Burke, ZD; Reed, KR; Phesse, TJ; Sansom, OJ; Clarke, AR; Tosh, D,期刊：Gastroenterology, 页码：2316-2324 , 文章类型： Article，,卷期：2009年136-7]
- Background and Aims: The Writ pathway has previously been shown to play a role in hepatic zonation. Herein, we have explored the role of 3 key components (Apc, beta-catenin, and c-Myc) of the Writ pathway in the zonation...
- Sensitive and Specific Detection of Early Gastric Cancer with DNA Methylation Analysis of Gastric Washes
[作者：Watanabe, Y; Kim, HS; Castoro, RJ; Chung, W; Estecio, MRH; Kondo, K; Guo, Y; Ahmed, SS; Toyota, M; Itoh, F; Suk, KT; Cho, MY; Shen, LL; Jelinek, J; Issa, JPJ,期刊：Gastroenterology, 页码：2149-2158 , 文章类型： Article，,卷期：2009年136-7]
- Background & Aims: Aberrant DNA methylation is an early and frequent process in gastric carcinogenesis and could be useful for detection of gastric neoplasia. We hypothesized that methylation analysis of DNA recovered fr...
- Disruption of Dicer1 Induces Dysregulated Fetal Gene Expression and Promotes Hepatocarcinogenesis
[作者：Sekine, S; Ogawa, R; Ito, R; Hiraoka, N; McManus, MT; Kanai, Y; Hebrok, M,期刊：Gastroenterology, 页码：2304-2315 , 文章类型： Article，,卷期：2009年136-7]
- Background & Aims: Growing evidence suggests that microRNAs coordinate various biological processes in the liver. We describe experiments to address the physiologic roles of these new regulators of gene expression in the...
- Efficacy of L-Ornithine L-Aspartate in Acute Liver Failure: A Double-Blind, Randomized, Placebo-Controlled Study
[作者：Acharya, SK; Bhatia, V; Sreenivas, V; Khanal, S; Panda, SK,期刊：Gastroenterology, 页码：2159-2168 , 文章类型： Article，,卷期：2009年136-7]
- Background & Aims: In acute liver failure (ALF), high blood ammonia levels have been documented that correlate with mortality and complications. L-ornithine L-aspartate (LOLA) reduces ammonia levels by increasing hepatic...
- The HLA Alleles DRB1*13 and DQB1*06 Are Associated to Whipple's Disease
[作者：Martinetti, M; Biagi, F; Badulli, C; Feurle, GE; Muller, C; Moos, V; Schneider, T; Marth, T; Marchese, A; Trotta, L; Sachetto, S; Pasi, A; De Silvestri, A; Salvaneschi, L; Corazza, GR,期刊：Gastroenterology, 页码：2289-2294 , 文章类型： Article，,卷期：2009年136-7]
- Back-ground & Aims: Whipple's disease is a systemic, chronic, relapsing disorder caused by a combination of environmental (Tropheryma whipplei) and unknown host factors. Because it is a rare disease, the association betw...
- Extracellular and Intracellular Pattern Recognition Receptors Cooperate in the Recognition of Helicobacter pylori
[作者：Rad, R; Ballhorn, W; Voland, P; Eisenacher, K; Mages, J; Rad, L; Ferstl, R; Lang, R; Wagner, H; Schmid, RM; Bauer, S; Prinz, C; Kirschning, CJ; Krug, A,期刊：Gastroenterology, 页码：2247-2257 , 文章类型： Article，,卷期：2009年136-7]
- Background & Aims: Helicobacter pylori infects half of the world's population, thereby causing significant human morbidity and mortality. The mechanisms by which professional antigen-presenting cells recognize the microb...
- Interleukin-25 Inhibits Interleukin-12 Production and Th1 Cell-Driven Inflammation in the Gut
[作者：Caruso, R; Sarra, M; Stolfi, C; Rio, A; Fina, D; Fantini, MC; Pallone, F; MacDonald, TT; Monteleone, G,期刊：Gastroenterology, 页码：2270-2279 , 文章类型： Article，,卷期：2009年136-7]
Background & Aims: During the pathogenesis of Crohn's disease (CD), interleukin (IL)-12, a cytokine produced by mucosal CD14(+) monocyte-like cells, promotes tissue-damaging T helper cell (Th) 1-mediated inflammat...
- Intrahepatic Bile Ducts Develop According to a New Mode of Tubulogenesis Regulated by the Transcription Factor SOX9
[作者：Antoniou, A; Raynaud, P; Cordi, S; Zong, YW; Tronche, F; Stanger, BZ; Jacquemin, P; Pierreux, CE; Clotman, F; Lemaigre, FP,期刊：Gastroenterology, 页码：2325-2333 , 文章类型： Article，,卷期：2009年136-7]
- Background & Aims: A number of diseases are characterized by defective formation of the intrahepatic bile ducts. In the embryo, hepatoblasts differentiate to cholangiocytes, which give rise to the bile ducts. Here, we in...
- Fibronectin Stimulates Endothelin-1 Synthesis in Rat Hepatic Myofibroblasts via a Src/ERK-Regulated Signaling Pathway
[作者：Zhan, SX; Chan, CC; Serdar, B; Rockey, DC,期刊：Gastroenterology, 页码：2345-2355 , 文章类型： Article，,卷期：2009年136-7]
- Background & Aims: Liver injury serves as an excellent model of wound healing, characterized by increased synthesis of various cytokines and peptides, including the vasoactive peptide endothelin-1. In the liver, wound he...
- Heterogeneities in ICC Ca2+ Activity Within Canine Large Intestine
[作者：Lee, HT; Hennig, GW; Park, KJ; Bayguinov, PO; Ward, SM; Sanders, KM; Smith, TK,期刊：Gastroenterology, 页码：2226-2236 , 文章类型： Article，,卷期：2009年136-7]
- Background & Aims: In human and canine colon, both slow (slow waves, 2-8/min) and fast (myenteric potential oscillations [MPOs]; 16-20/min) electrical rhythms in the smooth muscle originate at the submucosal and myenteri...
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