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  • Chromosome 8q23.3 and 11q23.1 Variants Modify Colorectal Cancer Risk in Lynch Syndrome
    [作者:Wijnen, JT; Brohet, RM; Van Eijk, R; Jagmohan-Changur, S; Middeldorp, A; Tops, CM; Van Puijenbroek, M; Ausems, MGEM; Garcia, EG; Hes, FJ; Hoogerbrugge, N; Menko, FH; Van Os, TAM; Sijmons, RH; Verhoef, S; Wagner, A; Nagengast, FM; Kleibeuker, JH; Devilee, P; Morreau, H; Goldgar, D; Tomlinson, IP; Houlston, RS; Van Wezel, T; Vasen, HFA,期刊:Gastroenterology, 页码:131-137 , 文章类型: Article,,卷期:2009年136-1]
  • Background & Aims: Recent genome-wide association studies have identified common low-risk variants for colorectal cancer (CRC). To assess whether these influence CRC risk in the Lynch syndrome, we genotyped these variant...
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