- Radiodefluorination of 3-Fluoro-5-(2-(2-[18F](fluoromethyl)-thiazol-4-yl)ethynyl)benzonitrile ([18F]SP203), a Radioligand for Imaging Brain Metabotropic Glutamate Subtype-5 Receptors with Positron Emission Tomography, Occurs by Glutathionylation in Rat Brain (vol 327, pg 727, 2008)
[作者:Shetty, HU; Zoghbi, SS; Simeon, FG; Liow, JS; Brown, AK; Kannan, P; Innis, RB; Pike, VW,期刊:Journal of Pharmacology and Experimental Therapeutics, 页码:1019-1019 , 文章类型: Correction,,卷期:2009年328-3]
- The Modulation of Synaptic GABA(A) Receptors in the Thalamus by Eszopiclone and Zolpidem
[作者:Jia, F; Goldstein, PA; Harrison, NL,期刊:Journal of Pharmacology and Experimental Therapeutics, 页码:1000-1006 , 文章类型: Article,,卷期:2009年328-3]
Eszopiclone (Lunesta; Sepracor, Marlborough, MA) and zolpidem [N,N,6-trimethyl-2-(4-methylphenyl)-imidazo(1,2-a)pyridine-3-acetamide] are among the most commonly prescribed hypnotics in use in the United States. The t...
- Improved Antiulcer and Anticancer Properties of a trans-Resveratrol Analog in Mice
[作者:Guha, P; Dey, A; Sarkar, B; Dhyani, MV; Chattopadhyay, S; Bandyopadhyay, SK,期刊:Journal of Pharmacology and Experimental Therapeutics, 页码:829-838 , 文章类型: Article,,卷期:2009年328-3]
Despite its potential, use of trans-resveratrol as an anticancer drug is severely constrained because of its tendency to prolong gastric ulceration. We found that in addition to delaying ulcer healing, trans-resveratr...
- Involvement of Extracellular Signal-Regulated Kinase Activation in Human Osteosarcoma Cell Resistance to the Histone Deacetylase Inhibitor FK228 [(1S,4S,7Z,10S,16E,21R)-7-Ethylidene-4,21-bis(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone]
[作者:Matsubara, H; Watanabe, M; Imai, T; Yui, Y; Mizushima, Y; Hiraumi, Y; Kamitsuji, Y; Watanabe, K; Nishijo, K; Toguchida, J; Nakahata, T; Adachi, S,期刊:Journal of Pharmacology and Experimental Therapeutics, 页码:839-848 , 文章类型: Article,,卷期:2009年328-3]
The histone deacetylase inhibitor depsipeptide [(1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-bis(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone] (FK228) has attracted a g...
- Identification and Quantification of 2 ',3 '-cAMP Release by the Kidney
[作者:Ren, J; Mi, ZC; Stewart, NA; Jackson, EK,期刊:Journal of Pharmacology and Experimental Therapeutics, 页码:855-865 , 文章类型: Article,,卷期:2009年328-3]
We recently developed a sensitive assay for 3',5'-cAMP using high-performance liquid chromatography-tandem mass spectrometry. Using this assay, we investigated the release of 3',5'-cAMP from isolated, perfused rat kid...
- Characterization of Serotonin Receptors in Pregnant Human Myometrium
[作者:Cordeaux, Y; Pasupathy, D; Bacon, J; Charnock-Jones, DS; Smith, GCS,期刊:Journal of Pharmacology and Experimental Therapeutics, 页码:682-691 , 文章类型: Article,,卷期:2009年328-3]
The monoamine, 5-hydroxytryptamine (5-HT), stimulates contraction of human uterine smooth muscle (myometrium), but the receptor subtypes involved have not been characterized. We studied the effects of a range of 5-HT ...
- Ethanol Withdrawal Provokes Opening of the Mitochondrial Membrane Permeability Transition Pore in an Estrogen-Preventable Manner
[作者:Jung, ME; Wilson, AM; Ju, XH; Wen, Y; Metzger, DB; Simpkins, JW,期刊:Journal of Pharmacology and Experimental Therapeutics, 页码:692-698 , 文章类型: Article,,卷期:2009年328-3]
We have reported that the major endogenous estrogen, 17 beta-estradiol (E2), protects against oxidative injury during ethanol withdrawal (EW) in a cultured hippocampal cell line (HT22). Here, we investigated whether t...
|