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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共13条记录   On the Relationship between Diffraction Patterns and Motions in Macromolecular Crystals [作者：Moore, PB,期刊：Structure, 页码：1307-1315 , 文章类型： Article，,卷期：2009年17-10] The quality of many macromolecular crystal structures published recently has been enhanced through the use of new methods for treating the effects of molecular motion and disorder on diffraction patterns, among them a te... Conformation Dependence of Backbone Geometry in Proteins [作者：Berkholz, DS; Shapovalov, MV; Dunbrack, RL; Karplus, PA,期刊：Structure, 页码：1316-1325 , 文章类型： Article，,卷期：2009年17-10] Protein structure determination and predictive modeling have long been guided by the paradigm that the peptide backbone has a single, context-independent ideal geometry. Both quantum-mechanics calculations and empirical ... Structure of the Human Dicer-TRBP Complex by Electron Microscopy [作者：Lau, PW; Potter, CS; Carragher, B; MacRae, IJ,期刊：Structure, 页码：1326-1332 , 文章类型： Article，,卷期：2009年17-10] Dicer is a specialized ribonuclease that initiates RNA interference (RNAi) by cleaving double-stranded RNA (dsRNA) into small RNA fragments about 22 nucleotides long. Here, we present the three-dimensional structure of h... Structure of PAS-Linked Histidine Kinase and the Response Regulator Complex [作者：Yamada, S; Sugimoto, H; Kobayashi, M; Ohno, A; Nakamura, H; Shiro, Y,期刊：Structure, 页码：1333-1344 , 文章类型： Article，,卷期：2009年17-10] We determined the structure of the complex of the sensory histidine kinase (HK) and its cognate response regulator (RR) in the two-component signal transduction system of Thermotoga maritima. This was accomplished by fit... Structural Basis of Novel Interactions Between the Small-GTPase and GDI-like Domains in Prokaryotic FeoB Iron Transporter [作者：Hattori, M; Jin, YH; Nishimasu, H; Tanaka, Y; Mochizuki, M; Uchiumi, T; Ishitani, R; Ito, K; Nureki, O,期刊：Structure, 页码：1345-1355 , 文章类型： Article，,卷期：2009年17-10] The FeoB family proteins are widely distributed prokaryotic membrane proteins involved in Fe2+ uptake. FeoB consists of N-terminal cytosolic and C-terminal transmembrane domains. The N-terminal region of the cytosolic do... Intrinsic Domain and Loop Dynamics Commensurate with Catalytic Turnover in an Induced-Fit Enzyme [作者：Davulcu, O; Flynn, PF; Chapman, MS; Skalicky, JJ,期刊：Structure, 页码：1356-1367 , 文章类型： Article，,卷期：2009年17-10] Arginine kinase catalyzes reversible phosphoryl transfer between ATP and arginine, buffering cellular ATP concentrations. Structures of substrate-free and -bound enzyme have highlighted a range of conformational changes ... The Structure of a Bacterial DUF199/WhiA Protein: Domestication of an Invasive Endonuclease [作者：Kaiser, BK; Clifton, MC; Shen, BW; Stoddard, BL,期刊：Structure, 页码：1368-1376 , 文章类型： Article，,卷期：2009年17-10] Proteins of the DUF199 family, present in all Gram-positive bacteria and best characterized by the WhiA sporulation control factor in Streptomyces coelicolor, are thought to act as genetic regulators. The crystal structu... Structural Insights on the Mycobacterium tuberculosis Proteasomal ATPase Mpa [作者：Wang, T; Li, H; Lin, G; Tang, CY; Li, DY; Nathan, C; Darwin, KH; Li, HL,期刊：Structure, 页码：1377-1385 , 文章类型： Article，,卷期：2009年17-10] Proteasome-mediated protein turnover in all domains of life is an energy-dependent process that requires ATPase activity. Mycobacterium tuberculosis (Mtb) was recently shown to possess a ubiquitin-like proteasome pathway... Structural Plasticity of Eph Receptor A4 Facilitates Cross-Class Ephrin Signaling [作者：Bowden, TA; Aricescu, AR; Nettleship, JE; Siebold, C; Rahman-Huq, N; Owens, RJ; Stuart, DI; Jones, EY,期刊：Structure, 页码：1386-1397 , 文章类型： Article，,卷期：2009年17-10] The EphA4 tyrosine kinase cell surface receptor regulates an array of physiological processes and is the only currently known class A Eph receptor that binds both A and B class ephrins with high affinity. We have solved ... Structure of IL-33 and Its Interaction with the ST2 and IL-1RAcP Receptors-Insight into Heterotrimeric IL-1 Signaling Complexes [作者：Lingel, A; Weiss, TM; Niebuhr, M; Pan, B; Appleton, BA; Wiesmann, C; Bazan, JF; Fairbrother, WJ,期刊：Structure, 页码：1398-1410 , 文章类型： Article，,卷期：2009年17-10] Members of the interleukin-1 (IL-1) family of cytokines play major roles in host defense and immune system regulation in infectious and inflammatory diseases. IL-1 cytokines trigger a biological response in effector cell... OMP Peptides Activate the DegS Stress-Sensor Protease by a Relief of Inhibition Mechanism [作者：Sohn, J; Grant, RA; Sauer, RT,期刊：Structure, 页码：1411-1421 , 文章类型： Article，,卷期：2009年17-10] In the E. coli periplasm, C-terminal peptides of misfolded outer-membrane porins (OMPs) bind to the PDZ domains of the trimeric DegS protease, triggering cleavage of a transmembrane regulator and transcriptional activati... Structure and Signaling Mechanism of Per-ARNT-Sim Domains [作者：Moglich, A; Ayers, RA; Moffat, K,期刊：Structure, 页码：1282-1294 , 文章类型： Review，,卷期：2009年17-10] Per-ARNT-Sim (PAS) domains serve as versatile sensor and interaction modules in signal transduction proteins. PAS sensors detect chemical and physical stimuli and regulate the activity of functionally diverse effector do... Discovery Through the Computational Microscope [作者：Lee, EH; Hsin, J; Sotomayor, M; Comellas, G; Schulten, K,期刊：Structure, 页码：1295-1306 , 文章类型： Review，,卷期：2009年17-10] All-atom molecular dynamics simulations have become increasingly popular as a tool to investigate protein function and dynamics. However, researchers are concerned about the short time scales covered by simulations, the ...