个性化文献订阅>文章检索

文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共15条记录   Classic limb patterning models and the work of Dennis Summerbell [作者：Galloway, JL; Tabin, CJ,期刊：Development, 页码：2683-2687 , 文章类型： Article，,卷期：2008年135-16] Dennis Summerbell was a leading contributor to our understanding of limb patterning prior to the advent of molecular biology. He published several groundbreaking papers, including one that developed a key model for patte... Tissue-specific requirements of beta-catenin in external genitalia development [作者：Lin, CX; Yin, Y; Long, FX; Ma, L,期刊：Development, 页码：2815-2825 , 文章类型： Article，,卷期：2008年135-16] External genitalia are body appendages specialized for internal fertilization. Their development can be divided into two phases, an early androgen-independent phase and a late androgen-dependent sexual differentiation ph... Functional diversity and mechanisms of action of the semaphorins [作者：Eickholt, BJ,期刊：Development, 页码：2689-2694 , 文章类型： Editorial Material，,卷期：2008年135-16] The second EMBO workshop on 'Semaphorin function and mechanisms of action', held in the gorgeous surroundings of the 12th Century Abbaye des Vaulx de Cernay near Paris, France this May, brought together a wide range of s... Dynamic Fgf signaling couples morphogenesis and migration in the zebrafish lateral line primordium [作者：Lecaudey, V; Cakan-Akdogan, G; Norton, WHJ; Gilmour, D,期刊：Development, 页码：2695-2705 , 文章类型： Article，,卷期：2008年135-16] The collective migration of cells in the form of cohesive tissues is a hallmark of both morphogenesis and repair. The extrinsic cues that direct these complex migrations usually act by regulating the dynamics of a specif... The Ecdysone-inducible zinc-finger transcription factor Crol regulates Wg transcription and cell cycle progression in Drosophila [作者：Mitchell, N; Cranna, N; Richardson, H; Quinn, L,期刊：Development, 页码：2707-2716 , 文章类型： Article，,卷期：2008年135-16] The steroid hormone Ecdysone is crucial for developmental cell death, proliferation and morphogenesis in Drosophila. Herein, we delineate a molecular pathway linking Ecdysone signalling to cell cycle regulation in the Dr... Hedgehog signaling is involved in development of the neocortex [作者：Komada, M; Saitsu, H; Kinboshi, M; Miura, T; Shiota, K; Ishibashi, M,期刊：Development, 页码：2717-2727 , 文章类型： Article，,卷期：2008年135-16] Sonic hedgehog (Shh) function is essential for patterning and cell fate specification, particularly in ventral regions of the central nervous system. It is also a crucial mitogen for cerebellar granule neuron precursors ... Maternal depletion of CTCF reveals multiple functions during oocyte and preimplantation embryo development [作者：Wan, LB; Pan, H; Hannenhalli, S; Cheng, Y; Ma, J; Fedoriw, A; Lobanenkov, V; Latham, KE; Schultz, RM; Bartolomei, MS,期刊：Development, 页码：2729-2738 , 文章类型： Article，,卷期：2008年135-16] CTCF is a multifunctional nuclear factor involved in epigenetic regulation. Despite recent advances that include the systematic discovery of CTCF-binding sites throughout the mammalian genome, the in vivo roles of CTCF i... Dap160/intersectin binds and activates aPKC to regulate cell polarity and cell cycle progression [作者：Chabu, C; Doe, CQ,期刊：Development, 页码：2739-2746 , 文章类型： Article，,卷期：2008年135-16] The atypical protein kinase C (aPKC) is required for cell polarization of many cell types, and is upregulated in several human tumors. Despite its importance in cell polarity and growth control, relatively little is know... The C-elegans F-spondin family protein SPON-1 maintains cell adhesion in neural and non-neural tissues [作者：Woo, WM; Berry, EC; Hudson, ML; Swale, RE; Goncharov, A; Chisholm, AD,期刊：Development, 页码：2747-2756 , 文章类型： Article，,卷期：2008年135-16] The F-spondin family of extracellular matrix proteins has been implicated in axon outgrowth, fasciculation and neuronal cell migration, as well as in the differentiation and proliferation of non-neuronal cells. In screen... Conditional ablation of Notch signaling in pancreatic development [作者：Nakhai, H; Siveke, JT; Klein, B; Mendoza-Torres, L; Mazur, PK; Algul, H; Radtke, F; Strobl, L; Zimber-Strobl, U; Schmid, RM,期刊：Development, 页码：2757-2765 , 文章类型： Article，,卷期：2008年135-16] The role of the Notch signaling members Notch1, Notch2 and Rbpj in exocrine pancreatic development is not well defined. We therefore analyzed conditional pancreas-specific Rbpj and combined Notch1/Notch2 knockout mice us... Hedgehog and Wingless stabilize but do not induce cell fate during Drosophila dorsal embryonic epidermal patterning [作者：Vincent, S; Perrimon, N; Axelrod, JD,期刊：Development, 页码：2767-2775 , 文章类型： Article，,卷期：2008年135-16] A fundamental concept in development is that secreted molecules such as Wingless (Wg) and Hedgehog (Hh) generate pattern by inducing cell fate. By following markers of cellular identity posterior to the Wg- and Hh-expres... Crucial role of vHNF1 in vertebrate hepatic specification [作者：Lokmane, L; Haumaitre, C; Garcia-Villalba, P; Anselme, I; Schneider-Maunoury, S; Cereghini, S,期刊：Development, 页码：2777-2786 , 文章类型： Article，,卷期：2008年135-16] Mouse liver induction occurs via the acquisition of ventral endoderm competence to respond to inductive signals from adjacent mesoderm, followed by hepatic specification. Little is known about the regulatory circuit invo... Cell-type-specific transcription of prospero is controlled by combinatorial signaling in the Drosophila eye [作者：Hayashi, T; Xu, CY; Carthew, RW,期刊：Development, 页码：2787-2796 , 文章类型： Article，,卷期：2008年135-16] In Drosophila, Notch and Egfr signaling regulate the determination of many cell types, and yet how these common signals generate cell-specific transcription is not well understood. In the compound eye, prospero ( pros) i... BMP2 and BMP7 play antagonistic roles in feather induction [作者：Michon, F; Forest, L; Collomb, E; Demongeot, J; Dhouailly, D,期刊：Development, 页码：2797-2805 , 文章类型： Article，,卷期：2008年135-16] Feathers, like hairs, first appear as primordia consisting of an epidermal placode associated with a dermal condensation that is necessary for the continuation of their differentiation. Previously, the BMPs have been pro... Origin and shaping of the laterality organ in zebrafish [作者：Oteiza, P; Koeppen, M; Concha, ML; Heisenberg, CP,期刊：Development, 页码：2807-2813 , 文章类型： Article，,卷期：2008年135-16] Handedness of the vertebrate body plan critically depends on transient embryonic structures/ organs that generate cilia-dependent leftward fluid flow within constrained extracellular environments. Although the function o...