- Mammalian target of rapamycin activation underlies HSC defects in autoimmune disease and inflammation in mice
[作者：Chen, C; Liu, Y; Liu, Y; Zheng, P,期刊：Journal of clinical investigation, 页码：4091-4101 , 文章类型： Article，,卷期：2010年120-11]
- The mammalian target of rapamycin (mTOR) is a signaling molecule that senses environmental cues, such as nutrient status and oxygen supply, to regulate cell growth, proliferation, and other functions. Unchecked, sustaine...
- What is this thing called pain?
[作者：Woolf, CJ,期刊：Journal of clinical investigation, 页码：3742-3744 , 文章类型： Editorial Material，,卷期：2010年120-11]
- To paraphrase Cole Porter's famous 1926 song, "What is this thing called pain? This funny thing called pain, just who can solve its mystery?" Pain, like love, is all consuming: when you have it, not much else matters, an...
- Pain as a channelopathy
[作者：Raouf, R; Quick, K; Wood, JN,期刊：Journal of clinical investigation, 页码：3745-3752 , 文章类型： Review，,卷期：2010年120-11]
- Mendelian heritable pain disorders have provided insights into human pain mechanisms and suggested new analgesic drug targets. Interestingly, many of the heritable monogenic pain disorders have been mapped to mutations i...
- Labeled lines meet and talk: population coding of somatic sensations
[作者：Ma, QF,期刊：Journal of clinical investigation, 页码：3773-3778 , 文章类型： Review，,卷期：2010年120-11]
- The somatic sensory system responds to stimuli of distinct modalities, including touch, pain, itch, and temperature sensitivity. In the past century, great progress has been made in understanding the coding of these sens...
- Central modulation of pain
[作者：Ossipov, MH; Dussor, GO; Porreca, F,期刊：Journal of clinical investigation, 页码：3779-3787 , 文章类型： Review，,卷期：2010年120-11]
- It has long been appreciated that the experience of pain is highly variable between individuals. Pain results from activation of sensory receptors specialized to detect actual or impending tissue damage (i.e., nociceptor...
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