- Concise Review: Adipocyte Origins: Weighing the Possibilities
[作者:Majka, SM; Barak, Y; Klemm, DJ,期刊:Stem Cells, 页码:1034-1040 , 文章类型: Review,,卷期:2011年29-7]
- Adipose tissue is the primary energy reservoir in the body and an important endocrine organ that plays roles in energy homeostasis, feeding, insulin sensitivity, and inflammation. While it was tacitly assumed that fat in...
- Development of Histocompatible Primate-Induced Pluripotent Stem Cells for Neural Transplantation
[作者:Deleidi, M; Hargus, G; Hallett, P; Osborn, T; Isacson, O,期刊:Stem Cells, 页码:1052-1063 , 文章类型: Article,,卷期:2011年29-7]
- Immune rejection and risk of tumor formation are perhaps the greatest hurdles in the field of stem cell transplantation. Here, we report the generation of several lines of induced pluripotent stem cells (iPSCs) from cyno...
- Mitochondria Determine the Differentiation Potential of Cardiac Mesoangioblasts
[作者:San Martin, N; Cervera, AM; Cordova, C; Covarello, D; McCreath, KJ; Galvez, BG,期刊:Stem Cells, 页码:1064-1074 , 文章类型: Article,,卷期:2011年29-7]
- An understanding of cardiac progenitor cell biology would facilitate their therapeutic potential for cardiomyocyte restoration and functional heart repair. Our previous studies identified cardiac mesoangioblasts as preco...
- Combined Effects of Hematopoietic Progenitor Cell Mobilization from Bone Marrow by Granulocyte Colony Stimulating Factor and AMD3100 and Chemotaxis into the Brain Using Stromal Cell-Derived Factor-1 alpha in an Alzheimer's Disease Mouse Model
[作者:Shin, JW; Lee, JK; Lee, JE; Min, WK; Schuchman, EH; Jin, HK; Bae, JS,期刊:Stem Cells, 页码:1075-1089 , 文章类型: Article,,卷期:2011年29-7]
- Transplantation of bone marrow-derived stem cells (BMSCs) has been suggested as a potential therapeutic approach to prevent neurodegenerative diseases, but it remains problematic due to issues of engraftment, potential t...
- p53 Directly Represses Id2 to Inhibit the Proliferation of Neural Progenitor Cells
[作者:Paolella, BR; Havrda, MC; Mantani, A; Wray, CM; Zhang, ZH; Israel, MA,期刊:Stem Cells, 页码:1090-1101 , 文章类型: Article,,卷期:2011年29-7]
- Neural progenitor cells (NPCs) have the capacity to proliferate and give rise to all major central nervous system cell types and represent a possible cell of origin in gliomagenesis. Deletion of the tumor suppressor gene...
- Fibroblast Growth Factor 2 (Fgf2) Inhibits Differentiation of Mesenchymal Stem Cells by Inducing Twist2 and Spry4, Blocking Extracellular Regulated Kinase Activation, and Altering Fgf Receptor Expression Levels
[作者:Lai, WT; Krishnappa, V; Phinney, DG,期刊:Stem Cells, 页码:1102-1111 , 文章类型: Article,,卷期:2011年29-7]
- Mesenchymal stem cells (MSCs) are known to differentiate into connective tissue lineages but intracellular signaling pathways that maintain cells in an undifferentiated state remain largely unexplored. Previously, we rep...
- Inhibition of Osteogenic Differentiation of Human Adipose-Derived Stromal Cells by Retinoblastoma Binding Protein 2 Repression of RUNX2-Activated Transcription
[作者:Ge, WS; Shi, L; Zhou, YS; Liu, YS; Ma, GE; Jiang, Y; Xu, YW; Zhang, X; Feng, HL,期刊:Stem Cells, 页码:1112-1125 , 文章类型: Article,,卷期:2011年29-7]
- Histone methylation is regarded as an important type of histone modification defining the epigenetic program during the lineage differentiation of stem cells. A better understanding of this epigenetic mechanism that gove...
- Enhanced Neural Progenitor/Stem Cells Self-Renewal via the Interaction of Stress-Inducible Protein 1 with the Prion Protein
[作者:Santos, TG; Silva, IR; Costa-Silva, B; Lepique, AP; Martins, VR; Lopes, MH,期刊:Stem Cells, 页码:1126-1136 , 文章类型: Article,,卷期:2011年29-7]
- Prion protein (PrPC), when associated with the secreted form of the stress-inducible protein 1 (STI1), plays an important role in neural survival, neuritogenesis, and memory formation. However, the role of the PrPC-STI1 ...
- Bone Marrow-Derived Mesenchymal Stromal Cells Inhibit Th2-Mediated Allergic Airways Inflammation in Mice
[作者:Goodwin, M; Sueblinvong, V; Eisenhauer, P; Ziats, NP; LeClair, L; Poynter, ME; Steele, C; Rincon, M; Weiss, DJ,期刊:Stem Cells, 页码:1137-1148 , 文章类型: Article,,卷期:2011年29-7]
- Bone marrow-derived mesenchymal stromal cells (BMSCs) mitigate inflammation in mouse models of acute lung injury. However, specific mechanisms of BMSC actions on CD4 T lymphocyte-mediated inflammation in vivo remain poor...
- Mesenchymal Stem Cell-Mediated Delivery of the Sodium Iodide Symporter Supports Radionuclide Imaging and Treatment of Breast Cancer
[作者:Dwyer, RM; Ryan, J; Havelin, RJ; Morris, JC; Miller, BW; Liu, ZL; Flavin, R; O'Flatharta, C; Foley, MJ; Barrett, HH; Murphy, JM; Barry, FP; O'Brien, T; Kerin, MJ,期刊:Stem Cells, 页码:1149-1157 , 文章类型: Article,,卷期:2011年29-7]
- Mesenchymal Stem Cells (MSCs) migrate specifically to tumors in vivo, and coupled with their capacity to bypass immune surveillance, are attractive vehicles for tumor-targeted delivery of therapeutic agents. This study a...
- Brief Report: Efficient Generation of Hematopoietic Precursors and Progenitors from Human Pluripotent Stem Cell Lines
[作者:Woods, NB; Parker, AS; Moraghebi, R; Lutz, MK; Firth, AL; Brennand, KJ; Berggren, WT; Raya, A; Belmonte, JCI; Gage, FH; Verma, IM,期刊:Stem Cells, 页码:1158-1164 , 文章类型: Article,,卷期:2011年29-7]
- By mimicking embryonic development of the hematopoietic system, we have developed an optimized in vitro differentiation protocol for the generation of precursors of hematopoietic lineages and primitive hematopoietic cell...
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