- Premature Ovarian Failure and Fertility in Long-Term Survivors of Hodgkin's Lymphoma: A European Organisation for Research and Treatment of Cancer Lymphoma Group and Groupe d'Etude des Lymphomes de l'Adulte Cohort Study
[作者:van der Kaaij, MAE; Heutte, N; Meijnders, P; Abeilard-Lemoisson, E; Spina, M; Moser, EC; Allgeier, A; Meulemans, B; Simons, AHM; Lugtenburg, PJ; Aleman, BMP; Noordijk, EM; Ferme, C; Thomas, J; Stamatoullas, A; Fruchart, C; Brice, P; Gaillard, I; Bologna, S; Ong, F; Eghbali, H; Doorduijn, JK; Morschhauser, F; Sebban, C; Roesink, JM; Bouteloup, M; Van Hoof, A; Raemaekers, JMM; Henry-Amar, M; Kluin-Nelemans, HC,期刊:Journal of clinical oncology, 页码:291-299 , 文章类型: Article,,卷期:2012年30-3]
- Purpose In this large cohort of Hodgkin's lymphoma survivors with long follow-up, we estimated the impact of treatment regimens on premature ovarian failure (POF) occurrence and motherhood, including safety of nonalkylat...
- Treatment of Colorectal Peritoneal Carcinomatosis With Systemic Chemotherapy: A Pooled Analysis of North Central Cancer Treatment Group Phase III Trials N9741 and N9841
[作者:Franko, J; Shi, Q; Goldman, CD; Pockaj, BA; Nelson, GD; Goldberg, RM; Pitot, HC; Grothey, A; Alberts, SR; Sargent, DJ,期刊:Journal of clinical oncology, 页码:263-267 , 文章类型: Article,,卷期:2012年30-3]
- Purpose Symptoms and complications of metastatic colorectal cancer (mCRC) differ by metastatic sites. There is a paucity of prospective survival data for patients with peritoneal carcinomatosis colorectal cancer (pcCRC)....
- Rapid Radiographic and Clinical Improvement After Treatment of a MET-Amplified Recurrent Glioblastoma With a Mesenchymal-Epithelial Transition Inhibitor
[作者:Chi, AS; Batchelor, TT; Kwak, EL; Clark, JW; Wang, DL; Wilner, KD; Louis, DN; Iafrate, AJ,期刊:Journal of clinical oncology, 页码:E30-E33 , 文章类型: Article,,卷期:2012年30-3]
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- RAS Mutations Are Associated With the Development of Cutaneous Squamous Cell Tumors in Patients Treated With RAF Inhibitors
[作者:Oberholzer, PA; Kee, D; Dziunycz, P; Sucker, A; Kamsukom, N; Jones, R; Roden, C; Chalk, CJ; Ardlie, K; Palescandolo, E; Piris, A; MacConaill, LE; Robert, C; Hofbauer, GFL; McArthur, GA; Schadendorf, D; Garraway, LA,期刊:Journal of clinical oncology, 页码:316-321 , 文章类型: Article,,卷期:2012年30-3]
- Purpose RAF inhibitors are effective against melanomas with BRAF V600E mutations but may induce keratoacanthomas (KAs) and cutaneous squamous cell carcinomas (cSCCs). The potential of these agents to promote secondary ma...
- Risk Factors for Obesity in Adult Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study
[作者:Green, DM; Cox, CL; Zhu, L; Krull, KR; Srivastava, DK; Stovall, M; Nolan, VG; Ness, KK; Donaldson, SS; Oeffinger, KC; Meacham, LR; Sklar, CA; Armstrong, GT; Robison, LL,期刊:Journal of clinical oncology, 页码:246-255 , 文章类型: Article,,卷期:2012年30-3]
- Purpose Many Childhood Cancer Survivor Study (CCSS) participants are at increased risk for obesity. The etiology of their obesity is likely multifactorial but not well understood. Patients and Methods We evaluated the po...
- Phase I, Dose-Escalation Study of BKM120, an Oral Pan-Class I PI3K Inhibitor, in Patients With Advanced Solid Tumors
[作者:Bendell, JC; Rodon, J; Burris, HA; de Jonge, M; Verweij, J; Birle, D; Demanse, D; De Buck, SS; Ru, QHC; Peters, M; Goldbrunner, M; Baselga, J,期刊:Journal of clinical oncology, 页码:282-290 , 文章类型: Article,,卷期:2012年30-3]
- Purpose This phase I dose-escalation study investigated the maximum-tolerated dose (MTD), safety, preliminary activity, pharmacokinetics (PK), and pharmacodynamics of BKM120, a potent and highly specific oral pan-Class I...
- Phase I/II Trial and Pharmacokinetic Study of Cixutumumab in Pediatric Patients With Refractory Solid Tumors and Ewing Sarcoma: A Report From the Children's Oncology Group
[作者:Malempati, S; Weigel, B; Ingle, AM; Ahern, CH; Carroll, JM; Roberts, CT; Reid, JM; Schmechel, S; Voss, SD; Cho, SY; Chen, HX; Krailo, MD; Adamson, PC; Blaney, SM,期刊:Journal of clinical oncology, 页码:256-262 , 文章类型: Article,,卷期:2012年30-3]
- Purpose A phase I/II study of cixutumumab (IMC-A12) in children with refractory solid tumors was conducted. This study was designed to assess the toxicities, pharmacokinetics, and pharmacodynamics of cixutumumab in child...
- Safety and Efficacy of Combination Immunotherapy With Interferon Alfa-2b and Tremelimumab in Patients With Stage IV Melanoma
[作者:Tarhini, AA; Cherian, J; Moschos, SJ; Tawbi, HA; Shuai, YL; Gooding, WE; Sander, C; Kirkwood, JM,期刊:Journal of clinical oncology, 页码:322-328 , 文章类型: Article,,卷期:2012年30-3]
- Purpose We tested the hypothesis that the combination of tremelimumab and interferon alfa-2b acting via different and possibly synergistic mechanisms would overcome tumor immune tolerance and lead to significant and dura...
- Phase III Trial Comparing Capecitabine Plus Cisplatin Versus Capecitabine Plus Cisplatin With Concurrent Capecitabine Radiotherapy in Completely Resected Gastric Cancer With D2 Lymph Node Dissection: The ARTIST Trial
[作者:Lee, J; Lim, DH; Kim, S; Park, SH; Park, JO; Park, YS; Lim, HY; Choi, MG; Sohn, TS; Noh, JH; Bae, JM; Ahn, YC; Sohn, I; Jung, SH; Park, CK; Kim, KM; Kang, WK,期刊:Journal of clinical oncology, 页码:268-273 , 文章类型: Article,,卷期:2012年30-3]
- Purpose The ARTIST (Adjuvant Chemoradiation Therapy in Stomach Cancer) trial was the first study to our knowledge to investigate the role of postoperative chemoradiotherapy therapy in patients with curatively resected ga...
- Impact of Long-Term Serum Platinum Concentrations on Neuro- and Ototoxicity in Cisplatin-Treated Survivors of Testicular Cancer
[作者:Sprauten, M; Darrah, TH; Peterson, DR; Campbell, ME; Hannigan, RE; Cvancarova, M; Beard, C; Haugnes, HS; Fossa, SD; Oldenburg, J; Travis, LB,期刊:Journal of clinical oncology, 页码:300-307 , 文章类型: Article,,卷期:2012年30-3]
- Purpose Cisplatin-induced neurotoxicity and ototoxicity (NTX) are important adverse effects after chemotherapy for testicular cancer (TC). Although serum platinum is measurable years after therapy, its impact on NTX has ...
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