- The role of Hes genes in intestinal development, homeostasis and tumor formation
[作者:Ueo, T; Imayoshi, I; Kobayashi, T; Ohtsuka, T; Seno, H; Nakase, H; Chiba, T; Kageyama, R,期刊:Development, 页码:1071-1082 , 文章类型: Article,,卷期:2012年139-6]
- Notch signaling regulates intestinal development, homeostasis and tumorigenesis, but its precise downstream mechanism remains largely unknown. Here we found that inactivation of the Notch effectors Hes1, Hes3 and Hes5, b...
- The CDC25B phosphatase shortens the G2 phase of neural progenitors and promotes efficient neuron production
[作者:Peco, E; Escude, T; Agius, E; Sabado, V; Medevielle, F; Ducommun, B; Pituello, F,期刊:Development, 页码:1095-1104 , 文章类型: Article,,卷期:2012年139-6]
- During embryonic development, changes in cell cycle kinetics have been associated with neurogenesis. This observation suggests that specific cell cycle regulators may be recruited to modify cell cycle dynamics and influe...
- ETTIN (ARF3) physically interacts with KANADI proteins to form a functional complex essential for integument development and polarity determination in Arabidopsis
[作者:Kelley, DR; Arreola, A; Gallagher, TL; Gasser, CS,期刊:Development, 页码:1105-1109 , 文章类型: Article,,卷期:2012年139-6]
- KANADI (KAN) transcription factors promote abaxial cell fate throughout plant development and are required for organ formation during embryo, leaf, carpel and ovule development. ABERRANT TESTA SHAPE (ATS, or KAN4) is nec...
- Mirror represses pipe expression in follicle cells to initiate dorsoventral axis formation in Drosophila
[作者:Andreu, MJ; Gonzalez-Perez, E; Ajuria, L; Samper, N; Gonzalez-Crespo, S; Campuzano, S; Jimenez, G,期刊:Development, 页码:1110-1114 , 文章类型: Article,,卷期:2012年139-6]
- Dorsoventral (DV) axis formation in Drosophila begins with selective activation of EGFR, a receptor tyrosine kinase (RTK), in dorsal-anterior (DA) ovarian follicle cells. A critical event regulated by EGFR signaling is t...
- Role of motoneuron-derived neurotrophin 3 in survival and axonal projection of sensory neurons during neural circuit formation
[作者:Usui, N; Watanabe, K; Ono, K; Tomita, K; Tamamaki, N; Ikenaka, K; Takebayashi, H,期刊:Development, 页码:1125-1132 , 文章类型: Article,,卷期:2012年139-6]
- Sensory neurons possess the central and peripheral branches and they form unique spinal neural circuits with motoneurons during development. Peripheral branches of sensory axons fasciculate with the motor axons that exte...
- The metalloproteinase inhibitor Reck is essential for zebrafish DRG development
[作者:Prendergast, A; Linbo, TH; Swarts, T; Ungos, JM; McGraw, HF; Krispin, S; Weinstein, BM; Raible, DW,期刊:Development, 页码:1141-1152 , 文章类型: Article,,卷期:2012年139-6]
- The neural crest is a migratory, multipotent cell lineage that contributes to myriad tissues, including sensory neurons and glia of the dorsal root ganglia (DRG). To identify genes affecting cell fate specification in ne...
- SIK3 is essential for chondrocyte hypertrophy during skeletal development in mice
[作者:Sasagawa, S; Takemori, H; Uebi, T; Ikegami, D; Hiramatsu, K; Ikegawa, S; Yoshikawa, H; Tsumaki, N,期刊:Development, 页码:1153-1163 , 文章类型: Article,,卷期:2012年139-6]
- Chondrocyte hypertrophy is crucial for endochondral ossification, but the mechanism underlying this process is not fully understood. We report that salt-inducible kinase 3 (SIK3) deficiency causes severe inhibition of ch...
- Molecular mechanism underlying the regulatory specificity of a Drosophila homeodomain protein that specifies myoblast identity
[作者:Busser, BW; Shokri, L; Jaeger, SA; Gisselbrecht, SS; Singhania, A; Berger, MF; Zhou, B; Bulyk, ML; Michelson, AM,期刊:Development, 页码:1164-1174 , 文章类型: Article,,卷期:2012年139-6]
- A subfamily of Drosophila homeodomain (HD) transcription factors (TFs) controls the identities of individual muscle founder cells (FCs). However, the molecular mechanisms by which these TFs generate unique FC genetic pro...
- Cartilage-specific RBPj kappa-dependent and -independent Notch signals regulate cartilage and bone development
[作者:Kohn, A; Dong, YF; Mirando, AJ; Jesse, AM; Honjo, T; Zuscik, MJ; O'Keefe, RJ; Hilton, MJ,期刊:Development, 页码:1198-1212 , 文章类型: Article,,卷期:2012年139-6]
- The Notch signaling pathway has emerged as an important regulator of endochondral bone formation. Although recent studies have examined the role of Notch in mesenchymal and chondro-osteo progenitor cell populations, ther...
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