- New 29-nor-cycloartanes with a 3,4-seco- and a novel 2,3-seco-structure from the leaves of Sinocalycanthus chinensis
[作者:KASHIWADA YOSHIKI; NISHIMURA KAZUYA; KURIMOTO SHINICHIRO; TAKAISHI YOSHIHISA,期刊:Bioorganic & Medicinal Chemistry, 页码:2790-2796 , 文章类型: Article,,卷期:2011年19-9]
- Eight new triterpenoids, including sinocalycanchinensins A-E (1-5) with a 3,4-seco-29-nor-cycloartane skeleton, sinocalycanchinensin F (6) possessing a novel 2,3-seco-29-nor-cycloartane skeleton, and 29-nor-cycloartanes,...
- Development and SAR of functionally selective allosteric modulators of GABA(A) receptors
[作者:ALHAMBRA CRISTOBAL; BECKER CHRIS; BLAKE TIMOTHY; CHANG AMY HUIFANG; DAMEWOOD JAMES R JR; DANIELS THALIA; DEMBOFSKY BRUCE T; GURLEY DAVID A; HALL JAMES E; HERZOG KEITH J; HORCHLER CAREY L; OHNMACHT CYRUS J; SCHMIESING RICHARD JON; DUDLEY ADAM; RIBADENEIRA MARIA D; KNAPPENBERGER KATHERINE S; MACIAG CARLA; STEIN MARK M; CHOPRA MANINDER; LIU XIAODONG F; CHRISTIAN EDWARD P; ARRIZA JEFFREY L; CHAPDELAINE MARC J,期刊:Bioorganic & Medicinal Chemistry, 页码:2927-2938 , 文章类型: Article,,卷期:2011年19-9]
- Positive modulators at the benzodiazepine site of alpha 2- and alpha 3-containing GABA(A) receptors are believed to be anxiolytic. Through oocyte voltage clamp studies, we have discovered two series of compounds that are...
- Synthesis of 4 beta-carbamoyl epipodophyllotoxins as potential antitumour agents
[作者:KAMAL AHMED; KUMAR B ASHWINI; SURESH PAIDAKULA; JUVEKAR AARTI; ZINGDE SUREKHA,期刊:Bioorganic & Medicinal Chemistry, 页码:2975-2979 , 文章类型: Article,,卷期:2011年19-9]
- A series of new 4 beta-carbamoyl epipodophyllotoxin analogues have been synthesized and evaluated for their anticancer activity against eleven cancer cell lines including Zr-75-1, MCF7, KB, Gurav, DWD, Colo 205, A-549, H...
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